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National Repository of Grey Literature 2 records found  Search took 0.00 seconds. 
Segmentation of arterial wall in high resolution retinal images
 Polachová, Natálie ; Odstrčilík, Jan (referee) ; Kolář, Radim (advisor)
This thesis focuses on automatic segmentation of retinal arterial walls in images acquired using adaptive optics. Adaptive optics is a non-invasive imaging method that provides high lateral resolution and allows detailed observation of retinal microstructures, including arterial walls. This technology is crucial for early diagnosis of serious diseases such as arterial hypertension and diabetic retinopathy. The main objective of this work was to detect the arterial lumen and segment its walls. Morphological and filtration techniques were used for lumen detection. For arterial wall segmentation, brightness profiles along the detected lumen were analyzed and active contour and spline methods were used. The results show that the active contour segmentation method improves the accuracy of arterial wall detection, especially in high-contrast regions. This thesis summarizes the findings and proposes improvements in the detection of the inner side of the arterial wall, which reduces the segmentation success rate in this work.
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Perivascular adipose tissue in health and disease
 Pasáková, Kateřina ; Králová Lesná, Ivana (advisor) ; Janovská, Petra (referee)
Adipose tissue is the biggest endocrine organ in a human body. Its function and composition have been intensively studied due to the rising number of overweight people. The cells of adipose tissue are called adipocytes. The substances that are produced by them are termed adipokines - cytokines secreted by adipocytes. It is possible to distinguish several types of adipose tissue based on its composition - white, brown and transient beige, or based on its location - visceral, subcutaneous and perivascular. Perivascular adipose tissue surrounds most of the blood vessels. Its effect can be inflammatory or anti-inflammatory and it is involved in the process of regulation of vascular tone. Pathology of perivascular adipose tissue can lead to a development of diseases which can directly or indirectly affect the cardiovascular system, and thus it may represent one of the main causes of death in the Western world.
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