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Psychopathology of early-onset schizophrenia and its therapy with focus on atypical neuroleptics
Koblic Zedková, Iveta ; Hrdlička, Michal (advisor) ; Bareš, Martin (referee) ; Stárková, Libuše (referee)
OBJECTIVES: The aim of our study was to assess clinical presentation of early-onset schizophrenia spectrum disoders (EO-SSD), the time to first improvement and efficacy associated with selected atypical (AAPs) and typical (TAPs) antipsychotics, as well as two main side effects - weight gain and treatment-emergent extrapyramidal symptoms (EPSs) during the treatment in patients with EO-SSD. METHODS: This was a systematic chart review of all patients receiving routine clinical care in our department, with selected AAPs (risperidone, olanzapine, ziprasidone, quetiapine and clozapine) and TAPs (haloperidol, perphenazine and sulpiride), for schizophrenic psychoses, between 1997 and 2007. During this period, our review identified 173 patients (85 males, 88 females; mean age 15.8±1.6 years); their treatment included 297 treatment trials. Data on premorbid adjustment, prodromal symptoms and psychopathology at admission, as well as comorbidity were evaluated based on the patients' medical records. The time to first improvement could be estimated in 258 treatment trials; of these, 195 (76%) comprised AAPs and 63 (24%) TAPs. The time to first improvement was assessed in agreement with the methodology established for retrospective studies as the number of treatment days prior to the first record of improvement...
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Risk of malnutrition for people with schizophrenia
GIERTLOVÁ, Petra
Schizophrenia is a servus mental illness. The majority of people suffering from this illness require lifelong treatment. The prevalence of risk factors such as development of cardiovascular dinase, diabetes, dyslipidemia, overweight, obesity is higher with regard to the patiens with schizophrenia. A large number of these people have bad rating habits, lack of physical aktivity and nicotine dependence. The use of antipsychotik mediactions also contributes to increased storage of fat and overweight.This Bachelor Thesis consists of teoretici and practical part. The theoretical part, based on the professional literature, describes malnutrition, schizophrenia and its different types, treatment and risks associated with this illness. The practical part focuses on research the main objektive of wich is to find out the incidence of malnutrition among patiens with schizophrenia, the influence of antipsychotik medication and surfy whether the nursing staff at the Nursing home with special care in Libníč is sufficiently informed. The survey is accomplished by means of the qualitative method using non-standardized interview. Research file consists of data submitted by four general nurses from the aforementioned Nursing home. The analysis of health documentation reveals that the majority of schizophrenic patiens suffer from other illness, such as obesity, hypertension, diabetes and hyperlipidemia. The results of this surfy prove that nursing staff are sufficiently informed and aware of possible risk factors associated with the development of cardiovascular dinase with regard to the schizophrenic patiens due to incorrect rating nabits or antipsychotik medication. The interview with the nurses implicates that malnutrition is considered as undernourishment. Accordingly, they identify nutrition care with the work of nutrition therapist and his care of patient nutrition. The nurses are aware of nutrition support. However, they have low level of knowledge regarding the products of modular dietetics.The main objective of this work is to demonstrate that schizophrenic patiens are in Langer of higher mortality and morbidity rate, not only as a results of thein illness, but also due to the antipsychotik medication treatment and inappropriate life style. This is the mason why the nutrition care should not be marginalized, nor neglected during the treatment of mental illnesses.
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Social, ethical and psychological aspects of working with people with schizophrenia
ŽIŽKOVÁ, Petra
The work deals with a mental illness called schizophrenia. The thesis consists of two parts, the theoretical part and the practical part. The theoretical part has five chapters, it has focused mainly on the interconnectedness of social work, psychiatry, psychology and ethics. First, it describes schizophrenia in general - how begins the illness, it signs and symptoms, diagnosis, course and prognosis and treatment options. I am focusing on the psychiatric aspects of schizophrenia, the social aspect of the disease and the ethics codes of various disciplines. The practical part is research, which is based on the interpretation of the results of a quantitative research. I opted a questionnaire as a research technice. The aim of this questionnaire is to find out which general knowledges has the adult population about schizophrenia and which views of schizophrenia are prevailing.
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