|
|
Attending physicians awareness of the possibilities of orthotic - protectic treatment of diabetic foot syndrome
Potěšil, Jan ; Černý, Pavel (advisor) ; Pavlů, Dagmar (referee)
Title: Attending physicians' awareness of the possibilities of orthotic-prosthetic treatment of diabetic foot syndrome Objectives: Objective of the thesis was to find out the current level of knowledge about orthotic-prosthetic therapy of diabetic foot syndrome among doctors, their attitude, and common practice in this field. Methods: The research was based on KAP (knowledge, attitude and practice) type of descriptive study. Questionnaire survey was used to collect data. It was necessary to create a new questionnaire in accordance with WHO guidelines. It was anonymous and shared through electronic form. The survey lasted two months and it was completed by 79 specialists in various fields of medicine. Eleven of them had to be excluded from the research. Data analysis was made in Microsoft Excel 365. Results: Diabetic foot syndrome is a serious complication of diabetes, which threatens more and more people every year. According to the results of the study, doctors are aware of that and understand the importance of orthotic-prosthetic therapy in management of the syndrome. On the other hand, they think this kind of therapy is underused. Their knowledge in this field is average, especially about orthosis use. The good news is that they want to learn more about this kind of therapy. Doctors don't use...
|
|
|
Critical limb ischemia and autologous cell therapy in diabetic foot disease, pathogenesis of Charcot osteoarthopathy.
Němcová, Andrea ; Jirkovská, Alexandra (advisor) ; Polák, Jan (referee) ; Prázný, Martin (referee)
Diabetic foot disease (DFD) is a serious complication of diabetes and, along with critical limb ischemia, significantly exacerbates the prognosis of patients. Peripheral arterial disease in patients with diabetes has an atypical clinical course, its diagnosis is challenging and is one of the most common causes of morbidity and mortality of patients with DFD. The aim of this dissertation focused on the diagnosis and treatment of DFD was to identify a suitable method for evaluating the effect of autologous cell therapy (ACT), to assess options for early diagnosis of Charcot osteoarthropathy (COA) and, possibly, to establish the association between the incidence of cardiovascular disease and DFD. In our studies concerning therapeutic vasculogenesis, we observed a significant increase in the antiangiogenic factor endostatin after ACT in contrast to its unchanged levels after standard percutaneous transluminal angioplasty; the transient increase in endostatin seems to be a marker of therapeutic vasculogenesis after ACT. A benefit of using calf muscle perfusion scintigraphy in the assessment of microcirculation and ACT effect was not clearly demonstrated. By contrast, a promising method for the evaluation of microcirculation and the effect of revascularization after ACT was MR spectroscopy of calf...
|
guest ::
