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In vitro model of the cardiovascular periphery
Michálek, Martin ; Zeman, Radek (referee) ; Kohút, Jiří (advisor)
This thesis focuses on modeling of peripheral vascular network in vitro. To achieve this purpose, 2-element Windkessel model is developed. Ball valve was used to achieve resistance and compliance chamber was constructed. Ball valve and compliance chamber were then used in a mock circulatory loop with peristaltic pump. When compliance 2,18 mlmmHg was achieved and ball valve was closed according to it, real values of pulse, systolic,diastolic and mean pressure in systematic arteries were obtained. Compliance chamber altered pulse pressure and valve adjusted mean pressure. Pressure and flow waveforms were measured and input impedance was calculated and shown.
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Methods for respiration estimates from ECG signal
Mitrengová, Jana ; Mézl, Martin (referee) ; Králík, Martin (advisor)
The thesis deals with the realization of methods for estimation of the respiratory curve from the ECG signal. The first part of the thesis deals with the anatomy and physiology of the respiratory and cardiovascular system. In this part of the thesis are also described ways of the breathing monitoring. The second part of the thesis is dedicated to the description of individual methods for the ECG derived respiration. The third part deals with the realization of selected methods, application of method algorithms on real data and comparison of resulting respiratory curves with the respiratory signals available from the PhysioNet database. In conclusion, the individual methods are compared with each other.
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Medical standing devices
Vadják, Šimon ; Ronzhina, Marina (referee) ; Kolářová, Jana (advisor)
This bachelor‘s thesis deals with patient verticalization and medical standing devices, which we use for this purpose. These findings are particularly important for rehabilitation and nursing care and also for the development of new standing devices. The bachelor‘s thesis describes the basic con¬cepts of human motor skills, the effect of changing position on the human organism, an overview of medical standing devices and their comparison. Thesis deals with comparison of the technical pa¬rameters of two standing devices more closely, standing device BALANCE Trainer and STOJ. The final part is devoted to measuring blood pressure using the noninvasive, continuous method of measuring at a group of wheelchair users during verticalization. I created a program with a graphical interface which allows measured data to load, display and measure, in numerical compu-ting environment MATLAB (version 7.9.0-R2009B). The results were statistically tested in the same numerical computing environment.
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Influence of postural change to the pulse wave velocity in the upper limb
Sakmárová, Klára ; Hrušková, Jana (referee) ; Svačinová, Jana (advisor)
This thesis is devoted to the topic of pulse wave velocity in the upper limb based on changes in body position. The work includes a literature search from the mentioned area, where it focuses mainly on the cardiovascular system, the pulse wave, its propagation in the human body, the clinical significance of the pulse wave and the factors that affect it. Pulse wave examination has now become an important part of the preclinical diagnosis of atherosclerosis or arterial stiffness. Examination of the pulse wave velocity as well as examination of the vascular system as part of early diagnosis is highly desirable for the stratification of cardiovascular diseases and subsequent mortality. In this work we will evaluate the speed of the pulse wave based on the time distance between the oscillation R on the ECG and the passage of the pulse wave under the pressure sensor located on the finger. In the MATLAB, a software solution of selected procedures for ECG measurement and blood pressure recording heart rate after heart rate is made. The measured values on a group of volunteers are statistically processed and subsequently discussed.
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Literature search of possibilities of computational modelling of brain aneurysms
Lipenský, Zdeněk ; Polzer, Stanislav (referee) ; Burša, Jiří (advisor)
This bachelor thesis is focused on gathering general information about a cerebrovascular disorder called Cerebral Aneurysm (or also Brain Aneurysm) which is a medical condition consisting in an abnormal bulging outward of one of the arteries in the brain. The initial attention is given to the human cardiovascular system, a description of which is fatal for understanding the problem of brain aneurysm. The next attention is focused on the solution of eliminating the tension within the aneurysm by using knowledge gained in lectures "Flexibility and Strength II" during the sixth semester. The last chapter shows a summary of three works dealing with computational modeling of cerebral aneurysm.
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Artificial heart on the principle of gas accumulators
Kunický, Ondřej ; Fialová, Simona (referee) ; Pochylý, František (advisor)
The diploma thesis deals with the design of an artificial heart based on the principle of gas accumulators. The introductory part describes the anatomy and physiology of the human cardiovascular system, mechanical heart replacement and the basic properties of pneumatic mechanisms. Furthermore, there is shown the procedure of pneumatic circuit design and its simulation in the program Simulink. The experimental part contains verification of the functionality of the pneumatic circuit, designed the positive displacement pump, and the measured characteristics of both ventricles. The last part of the work deals with the reduction possibilities of dimensions and weight of the whole mechanism. There is also included computational modelling of the pneumatic circuit using helium as a working medium.
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ECG and PPG derived respiration estimation
Chmela, Radek ; Smital, Lukáš (referee) ; Králík, Martin (advisor)
This work deals with the estimation of the respiratory curve from ECG and PPG signals. The first part deals with the description and monitoring of electrical activity of the heart, physiology and methodology of respiratory sensing and photoplethysmography. The second part deals with methods of extracting respiratory cycle information from ECG and PPG recordings. The third part deals with the algorithmic implementation and evaluation of individual procedures for estimating the breath curve from both of the above-mentioned signals on records from the web PhysioNet. In the last part, the algorithms are compared and evaluated.
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The measurement of cardiovascular parameters
Žáková, Monika ; Kratochvíla, Jiří (referee) ; Nováková, Zuzana (advisor)
This paper summarizes the problems of physiology of the cardiovascular system, with a focus on cardiovascular measurements during physical activity. It describes the diagnostic tools Cardiovit AT-104 (Schiller, Switzerland) and PowerCube (Ganshorn, Germany), used to spiro-ergometry measurements. It provides options to export data and work with them. It proposed protocol for the measurement of a small group of volunteers, by which we measure basic diagnostic parameters before, during and after physical activity. The MATLAB application is created, allowing clear analysis of measurement records. The final part contains a statistical assessment affected by physical activity on the measured parameters and a comparison of results with the available literature.
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Generator of the Spatial Structure of the Cardiovascular System of the Human Hand Finger
Gajdoš, Samuel ; Goldmann, Tomáš (referee) ; Drahanský, Martin (advisor)
The work contains theoretical knowledge in the field of scanning the veins of the human finger as a biometric feature. In addition to the study of biometrics, the thesis also includes resources from the field of medicine, where it mainly studies the anatomy and distribution of organs in the human finger. Subsequently, the algorithm that was selected to generate the spatial structure of the cardiovascular system of the human finger is discussed. This is a Space Colonization algorithm that was not created for this purpose. However, with small modifications to the basic algorithm, this procedure proved to be relatively efficient and suitable for the given task. The work also describes the used programming environment Processing and its libraries, which were used in the implementation of the spatial model generator.
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