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Assessment of facial morphology in patients with orofacial clefts in relation to surgical protocols
Moslerová, Veronika ; Velemínská, Jana (advisor) ; Dostálová, Taťjana (referee) ; Katina, Stanislav (referee)
The presented thesis summarizes the results of research on craniofacial morphology in patients with facial cleft defects in relation to therapeutic approaches (Caganova et al., 2014; Dadáková et al., 2016; Hoffmannova et al., 2016; Hoffmannova et al., 2018; Moslerová et al., 2018). The effect of therapy in individuals with pathological growth disorders cannot be evaluated without detailed auxological studies of control subjects whose facial morphology, longitudinal changes, or manifestations of sexual dimorphism were evaluated upon similar methodology (Koudelová et al. 2015). Therefore, the thesis was conceived as a volume of six publications complemented with a general synthetic introduction into the area of study. Together, the thesis includes probands in a broad age spectrum from birth to 15 years with a total of 294 facial 3D scans, 36 tele-X-ray face images, 3D scans of 112 gypsum palate castings. The methods of geometric morphometry and multidimensional statistics prevail in the assessment. The main clinical part of the thesis deals with the influence of two types of surgery on the facial growth and development of patients with cleft palate, namely secondary spongioplasty (SS) and neonatal cheiloplasty (NCH). Neonatal cheiloplasty (NCH) is the surgery whose effects were studied from several...
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Assessment of facial morphology in patients with orofacial clefts in relation to surgical protocols
Moslerová, Veronika
The presented thesis summarizes the results of research on craniofacial morphology in patients with facial cleft defects in relation to therapeutic approaches (Caganova et al., 2014; Dadáková et al., 2016; Hoffmannova et al., 2016; Hoffmannova et al., 2018; Moslerová et al., 2018). The effect of therapy in individuals with pathological growth disorders cannot be evaluated without detailed auxological studies of control subjects whose facial morphology, longitudinal changes, or manifestations of sexual dimorphism were evaluated upon similar methodology (Koudelová et al. 2015). Therefore, the thesis was conceived as a volume of six publications complemented with a general synthetic introduction into the area of study. Together, the thesis includes probands in a broad age spectrum from birth to 15 years with a total of 294 facial 3D scans, 36 tele-X-ray face images, 3D scans of 112 gypsum palate castings. The methods of geometric morphometry and multidimensional statistics prevail in the assessment. The main clinical part of the thesis deals with the influence of two types of surgery on the facial growth and development of patients with cleft palate, namely secondary spongioplasty (SS) and neonatal cheiloplasty (NCH). Neonatal cheiloplasty (NCH) is the surgery whose effects were studied from several...
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Assessment of facial morphology in patients with orofacial clefts in relation to surgical protocols
Moslerová, Veronika ; Velemínská, Jana (advisor) ; Dostálová, Taťjana (referee) ; Katina, Stanislav (referee)
The presented thesis summarizes the results of research on craniofacial morphology in patients with facial cleft defects in relation to therapeutic approaches (Caganova et al., 2014; Dadáková et al., 2016; Hoffmannova et al., 2016; Hoffmannova et al., 2018; Moslerová et al., 2018). The effect of therapy in individuals with pathological growth disorders cannot be evaluated without detailed auxological studies of control subjects whose facial morphology, longitudinal changes, or manifestations of sexual dimorphism were evaluated upon similar methodology (Koudelová et al. 2015). Therefore, the thesis was conceived as a volume of six publications complemented with a general synthetic introduction into the area of study. Together, the thesis includes probands in a broad age spectrum from birth to 15 years with a total of 294 facial 3D scans, 36 tele-X-ray face images, 3D scans of 112 gypsum palate castings. The methods of geometric morphometry and multidimensional statistics prevail in the assessment. The main clinical part of the thesis deals with the influence of two types of surgery on the facial growth and development of patients with cleft palate, namely secondary spongioplasty (SS) and neonatal cheiloplasty (NCH). Neonatal cheiloplasty (NCH) is the surgery whose effects were studied from several...
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Evaluation of the palate morphology in bilatelar cleft lip and palate clefts with palatolaly
Hamtilová, Martina ; Velemínská, Jana (advisor) ; Ivanov, Ilija Christo (referee)
The diploma work was based on the evaluation of dental casts of patients with bilateral cleft lip and palate (BCLP) with a mean age of 10. Patients consist of two groups, patients without defect in speech and with speech impairment (palatolaly). Palatolalies in the literature are primarily associated with velopharyngeal insufficiency. The study tested the working hypothesis that in the failure of speech is involved a different, specific in some way, palatal shape. Dental casts were scanned using a laser scanner and analyzed by 3-D geometric morphometry and multivariate statistics: principal component analysis (PCA), linear regression analysis and finite element analysis (FESA). Using linear regression it was found that the shape of the palate is affected in younger individuals by age, and so had to be 5 patients excluded for further analysis. Patients with palatolaly have lower variability the palatal shape than patients without palatolalie, so their palates are similar to each other and have a specific shape. Palates are wider and lower than in individuals without speech disorder and they have a characteristic deepening behind the anterior part of the palate. We assume that these features in palate morphology primarily the lower arch and the substantial deepening are most likely to affect the...
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