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Motor skills in a student with developmental dysphasia at a younger school age
Strouhalová, Kateřina ; Klenková, Jiřina (advisor) ; Horynová, Jana (referee)
This diploma thesis focuses on motor skills of pupils with developmental language disorder in their middle childhood years. Theoretical part describes the characteristics typical for middle childhood pupil in areas of basic abilities and skills, learning process, emotional development, and socialization. Next chapter of the theoretical part concerns the motor skills of person and define movement skills of pupils with developmental language disorder. In last chapter the diagnosis of developmental language disorder is presented defined form several different points such as ethology, classification, diagnosis, therapy and prognosis. Empiric part of the thesis consists of two research methods, first the test of motor skills and second the survey. The test of motor skill is to provide data about movements skills of pupils with developmental language disorder. For this test was used the ability test provided by Sazka Olympijský víceboj. The ability test focuses on several individual parts of motor skills such as force, speed, coordination, dynamics (explosivity) and flexibility. The task of the survey is to accommodate the Physical education for pupils with developmental language disorder and describe special methods and approaches used by pedagogues during their classes. The in thesis defined goals were...
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Non-neuronal cell outgrowth in Caenorhabditis elegans model system
Smidžárová, Lucie ; Macůrková, Marie (advisor) ; Strouhalová, Kateřina (referee)
1 Abstract Oriented cell growth is an important process for regular tissue development, in which regulated changes in cell shapes occur. An important role in this mechanism is played by remodelling of cytoskeletal elements in the growing parts of the cell, which is regulated by many extracellular and intracellular factors. This bachelor's thesis is focused on oriented non-neuronal cells growth in the model organism Caenorhabditis elegans, specifically the growth of the excretory cell and the anchor cell invasion. The growth mechanism of the excretory canal cell is in many aspects similar to growth of neurons, however it also involves a unique mechanism of growth through extension of an intracellular lumen. In case of the anchor cell the growth mechanisms support the basement membrane disruption and invasive behavior reminiscent of metastatic cancer cells. Regulation of growth of these two cells thus could serve as a good model for human pathologies such as cystic kidney disease or cancer cell metastasis, and therefore further study in this area could lead to new insights into these diseases. At the end of the thesis, other non- neuronal cells with oriented growth in the model organism C.elegans are briefly described. Key words: cell outgrowth, excretory canal cell, anchor cell, signalling, cytoskeleton
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