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Pharmacy in the Czech Lands between 1929-1938/9
Valášková, Ladislava ; Rusek, Václav (advisor) ; Solich, Jan (referee) ; Drábek, Pavel (referee)
11. ZÁVĚREČNÉ SHRNUTÍ Ve sledovaném období je důležité vyzvednout hlavní vývojové momenty, které jsou určovány vzájemným poměrem dvou složek lékárnického stavu, majitelů lékáren a jejich zaměstnanců. Vnější a vnitřní podoba lékáren se začala modernizovat nejen pod vlivem časopisu "Praktický lékárník", který kladl důraz na racionální zařízení lékárny. To znamenalo vybavení jednoduché a zároveň funkční i estetické. V této oblasti se uplatnila řada významných architektů, především Václav Kubík, který byl autorem návrhů pro přibližně 40 lékáren. Úroveň práce lékáren v receptuře a lékárenské výrobě podporoval kontrolní systém representovaný Ústavem pro zkoumání léčiv, který byl založen v roce 1918. Přesto, že se potýkal hlavně s prostorovými a personálními potížemi, a přesto, že aplikace jeho výsledků nebyla pružná, přispěl svou činností k zlepšení úrovně lékárenské receptury. Určitou mezeru v systému kontroly se snažila vyplnit od r. 1934 "Experta - první společnost pro vědecké a racionální hodnocení léčiv". Její příspěvek je mj. ve snaze vyzvednout kvalitu domácích, továrně vyráběných LP, zvláště zavedením jejích biologické kontroly a v podnětu k zavedení zákonem regulované biologické kontroly LČ a LP. V sociální oblasti vystupoval problém platového zabezpečení kondicinujících lékárníků. Ti se domnívali, že...
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Drug policy - prices, settlements and participation
Davidová, Jana ; Solich, Jan (advisor) ; Foltán, Viliam (referee) ; Hartlová, Stanislava (referee)
ve Value in Health Participation on drug costs in the elderly in the Czech Republic Davidova, J.; Praznovcova, L.; Vlcek, J. In: Value in Health, Vol. 8 Issue 6 Page 615-A242, Supplement to ISPOR 8th Annual European Congress, Florence, Italy. November 2005 OBJECTIVES: Analysis of participation on drug costs in seniors in the Czech Republic in connection with seniors' social status (e.g. financial, household conditions). METHODS: Quota-sampled questionnaire-based interview with 450 respondents visiting pharmacy; Ratio men:women approximately 1:2; Age 60 years old and elder; 3 regions of the Czech Republic RESULTS: Most of respondents (60 %) live in households with their partners. Respondent's income was retirement pension in 80 %. Its average level was between 5001 and 7499CZK. Respondents used together 1651 medicines on physician's prescription in last four weeks. Overall co-payment for medicines was 31944CZK, e.g. 70CZK per patient. Only 27 % of respondents used fully reimbursed products. Respondents used together 273 OTC drugs in value of 12900CZK, e.g. 29CZK per patient. Average respondents spent on medicines 100CZK in last four weeks, e.g. between 2 and 1.3 % of their income. There were respondents, about 10 %, searching for the level of co-payment in several pharmacies and 8 % of respondents,...
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Registration of medicines
Šubová, Irena ; Solich, Jan (advisor) ; Portych, Jiří (referee)
Marketing authorization of medicinal products Mgr. Irena Šubová Charles University in Prague, Faculty of Pharmacy Hradec Králové, Department of Social and Clinical Pharmacy Marketing authorization of medicinal products is process when the quality, safety and efficiency of product are checked based on submitted documentation. Registration in the Czech Republic is according to law No.79/1997 and No.473/2000 and it is harmonized with directives and regulations of European Union. A generic drug is medicinal product which has same qualitative and quantitative composition, as for active substances and same dose as the original formulation and whose bioequivalence with the original formulation has been proven by relevant studies of bioavailability. Structure of documentation describing medicinal program have been given united format, so called Common Technical Document (CTD). Documentation is divided in to 5 modules. Module 1 includes Administrative Information and Prescribing Information and its content is given by national drug regulatory agencies, Module 2 includes Common Technical Document Summaries, Module 3 includes Quality data, Module 4 includes Non-clinical study reports and Module 5 Clinical Study Reports. Important part of Module 1 is Summary of Product Characteristics, which is approved summarized...
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Quality of life of seniors in a retirement home
Koudelová, Ivona ; Borkovcová, Jitka (advisor) ; Solich, Jan (referee) ; Vostrovská, Helena (referee)
This Bachelor's Thesis concentrates on problems referred to quality of life of seniors in a retirement home. The theoretical part of this Thesis aims at specification and definition of fundamental concepts, such as gerontology, aging and old age, gerontological nursing, quality of geriatric care, quality of life of old people and adjustment abilities of seniors. The empirical part of the Thesis deals with real conditions, quality of life and adjustment of seniors to a stay in a retirement home. A half-structured interview was used to do the research work. During the survey, 36 respondents were randomly selected from the Retirement Home in Světlá nad Sázavou.
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Význam volně prodejných léků se zvláštním důrazem na spotřebitelské chování seniorů
Dürk, Betina ; Kotlářová, Jana (referee) ; Solich, Jan (advisor)
Apothekerin Mgr. Betina Dürk: Importance of the OTC drugs - mainly the attitude of the elders The studies focused on self-medication, mainly with respect to the OTC drugs form one of the principal issues of the socilal pharmacy, mainly in he biggest group of the drug users - the elders. This thesis continuates a line of studies that have been performed at the Department of Social and Clinical Pharmacy of the Charles University in Prague - Faculty of Pharmacy in Hradec Králové. The aim is to gain data from another country which is the West Germany, the München region. The observation was provided during the 2008/2009 period by means of the questionnaires and the analysis of the database of the participating pharmacy as well. Theoretical part of the thesis deals with social pharmacy as a branch of science. It includes the review of the development of the German pharmacy - mainly the pharmacy practice, ageing of the population and the social policy. The issue of the need and consumption of drugs in the elders is underlined. The observation was performed first in the group A ( the questionnaire - return 65 % of 843 respondents from a big city compared with small towns as well), and then in the group B (random patients from the database of the participating pharmacy - about 300 people). For the...
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The medicaments containing pseudoephedrine - material for illegal production of metamphetamine
Havlíček, Stanislav ; Solich, Jan (referee) ; Kotlářová, Jana (advisor)
1 SUMMARY MEDICINE CONTAINING PSEUDOEPHEDRINE - RAW MATERIALS FOR CLANDESTINE PRODUCTION OF METHAMPHETAMINE Author: Havlíček S., Métis, Pharmacy in Stod, Czech Republic Tutor: Kotlářová J., Dept. of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Kralove, Charles University in Prague,Czech Republic In the Czech Republic, the clandestine methamphetamine (pervitin) production appeared in 1970s. Ephedrin used to be a main source for methamphetamine production till the factory for ephedrine output in Roztoky (in 2004) was closed down. Since this moment a pseudoephedrine gained from ordinarily available medicaments has become very popular base material for this illegal production. An expansion of the illicit "home-based" methamphetamine manufactories is supported by very easy accessibility and also by poor regulation of these medicaments containing pseudoephedrine Another reason is the low price of the legally obtainable medication: around 200 CZK per 1g of pseudoephedrine. Pharmacies have suddenly become suppliers of drug gangs. However, they cannot prevent such situation under current legislation. Tightening regulations may help to solve the problem, but it seems unlikely to happen taken into account the large profits at stake. Sales volume of pharmaceuticals containing pseudoephedrine (Modafen,...
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