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Safety of selected dietary supplements with regard to the content of food additives I.
Rohlíková, Martina ; Pokladníková, Jitka (advisor) ; Marešová, Helena (referee)
Safety of the selected food supplements in terms of the presence of additives Additives are commonly present not only in food, but also in food supplements. Safety of these substances remains a question. The aim of the theses is to evaluate the safety of the best selling supplements in the Czech Republic in the year 2011 from the viewpoint of additives and constituents. Given the scale of researched products, I focused on products strengthening the cardiovascular system containing omega 3 fatty acids , garlic, coenzyme Q 10 and lecithin. As a source of information about the content and the presence of additives, the data from the Ministry of Health and the Information System decision of the Chief Hygienist (IS RoHy) were used. The safety evaluation of additives was carried out on the basis of the available methodology for consumers. Information about adverse effects of additives and content substances were searched using information databases Martindale , Reprotox, AltMedDex, Drugdex, National Center for Complementary and Alternative Medicine (NCCAM), IPCS INCHEM, PubMed independent commission database JECFA Joint FAO / WHO Expert committee on Food additives. Descriptive statistics was used. Of the large number of products (97), 5 products were classified as safe and 92 as products harmful to...
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Healthy lifestyle of people interested in healthy diet
Ondrášiková, Michaela ; Pokladníková, Jitka (advisor) ; Zubrová, Julie (referee)
Healthy lifestyle of people interested in healthy diet Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University, Czech Republic Student: Michaela Ondrášiková Tutor: PharmDr. Jitka Pokladníková, Ph.D. Introduction: The issue of a healthy lifestyle has been a highly discussed topic in recent years. It has not been examined in the Czech Republic for persons who are interested in healthy diet, as a specific group of people yet. Objectives: Primary goal of the thesis was to analyse lifestyle behaviors in persons who are interested in healthy diet and compare the data obtained with healthy eating and healthy lifestyle recommendations. Secondary goal of the thesis was to analyse quality of life, life satisfaction, mental hygiene and some aspects of physical health of persons who are interested in healthy diet. Methods: Data for this prospective cross-sectional questionnaire survey were obtained in the period from September 2012 to June 2015. Respondents from the general public attended free lectures held in the education cycle, focusing on healthy lifestyle in the project Ebstyle on Faculty of Pharmacy, Charles University. Data were evaluated according to healthy lifestyle and healthy diet criteria and processed in Microsoft Excel and IBM SPSS 19. Results: In...
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Attitudes and beliefs on HPV infection and vaccination
Blašková, Dominika ; Zimčíková, Eva (advisor) ; Pokladníková, Jitka (referee)
ATTITUDES AND KNOWLEDGE OF HPV INFECTION AND VACCINATION Author: Dominika Blašková Supervisor: PharmDr. Eva Zimčíková, Ph.D. INTRODUCTION Human papillomavirus (HPV) is a DNA virus. The virus causes benign and malignant diseases of men and women such as laryngeal papillomatosis, genital warts, oropharyngeal carcinoma, cervical cancer, penile cancer and anus cancer. HPV can be prevented by appropriate precautionary measures. The main preventative method is vaccination against HPV. Besides vaccination, regular screening is necessary to detect premalignant changes on time. AIMS The aim of the theoretical part of the diploma thesis was to summarize the information about HPV, the diseases caused by human papillomavirus and vaccination against HPV, the main preventive measure. The primary aim of the practical part was to find out the level of HPV awareness among girls and boys and diseases caused by HPV. The secondary aim of the practical part was to find out opinions on HPV vaccination and determine the rate of vaccination against HPV among young people in Slovakia. METHODS The method of quantitative research taken in the form of a questionnaire was used in the diploma thesis. The survey was realized at two secondary schools in Svidník, Slovakia. The age range of respondents was 15-20 years. The data...
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Aromatherapy and its favourite essential oils
Karra, Eirini ; Marešová, Helena (advisor) ; Pokladníková, Jitka (referee)
AROMATHERAPY AND ITS FAVOURITE ESSENTIAL OILS Student: Karra, E. Tutor: Marešová, H. Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University in Prague, Czech Republic Background: This thesis was made because I wanted to work on something different from what we are being taught at the Faculty of Pharmacy. But the topic should be near to the worlwide pharmacy practice. Nowadays many people are interested in Complementarey and Alternative Medicine (CAM). I decided to visit Dr. Marešová (a teaching practitioner at our Faculty) to ask her for a topic. She agreed and proposed Aromatherapy, and I found it quite interesting. During my work I started to realize how important and effective Aromatherapy may be, how easily it can be applied and become a part of our life. Aim: The aim of the thesis is to gain an understanding of what aromatherapy is and to show its benefits. Furthermore to introduce the substances (essential oils) that can be used and their availability, their several application forms and the various therapeutic effects. Nevertheless, essential oils may also be dangerous sometimes. For example, during pregnancy the use of some essential oils may be a problem and some oversensitive people may see an exacerbation of their allergies as well. Therefore,...
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Identification and analysis of therapy used by pregnant women
Pilková, Alena ; Malý, Josef (advisor) ; Pokladníková, Jitka (referee)
Identification and analysis of therapy used by pregnant women Author: Alena Pilková1,2 Tutor: Josef Malý2 1 Hospital pharmacy, Institute for the Care of Mother and Child, Prague 2 Department of Social and Clinical Pharmacy, Charles University in Prague, Faculty of Pharmacy in Hradec Králové Introduction and objective Pharmacotherapy in pregnancy is challenging due to the fact that when a mother uses any drug, her developing fetus is most likely exposed to that drug as well. There is not enough relevant data on the use of drugs and other therapeutic agents during pregnancy in the Czech Republic. The aim of this work was to identify and analyse drugs, food supplements, complementary and alternative medicine and information sources used by women during pregnancy. Methods An observational cross-sectional survey was conducted in three maternal wards of The Institute for the Care of Mother and Child in Prague. A questionnaire was distributed for 6 weeks during May and June 2015 to all women meeting the inclusion criteria. Comprehensibility of the questionnaire was verified by a pilot survey, these results were not included in the evaluation. The questionnaire consisted of 61 closed, semi-open and open questions and was accompanied by a letter with the inclusion criteria. The questionnaire was anonymous...
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An effect of non-specific factors on acupuncture effectiveness in patients with migraine
Talácková, Markéta ; Pokladníková, Jitka (advisor) ; Štefančíková, Mariana (referee)
1 Abstract Faculty of Pharmacy in Hradec Králové, Department of Social and Clinical Pharmacy, Charles University in Prague Student: Markéta Talácková Tutor: PharmDr. Jitka Pokladníková, Ph.D. Title of Rigorous Thesis: An effect of non-specific factors on acupuncture effectiveness in patients with migraine The aim of this study was to assess whether higher level of expectancy in patients with migraine leads to improvement of their clinical condition after a 12-week acupuncture course and during a 6-month follow-up. Patient's clinical condition was assessed as a number of migraine days and as a reduction in medication consumption. Other non-specific factors were included in this study as well. As the most significant non-specific factors, which contributed to an increased short-term effectiveness of acupuncture, were post-treatment positive expectancy and patient's mental state. However, the effect of positive expectancy decreased with time. The long-term effect of acupuncture was influenced by patient's positive perception of the TCM (Traditional Chinese medicine ) practitioner. Patient's expectancy, patient's relationship with the TCM physician and good mental state played a role in reduction of migraine days. Key words: acupuncture, migraine, reduction of migraine days, expectancy, non-specific factors,...
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Patients experience of acupuncture treatment III.
Maršálková, Zuzana ; Pokladníková, Jitka (advisor) ; Marešová, Helena (referee)
Faculty of Pharmacy in Hradec Králové, Department of Social and Clinical Pharmacy, Charles University, Czech Republic Student: Zuzana Maršálková Tutor: PharmDr. Jitka Pokladníková, Ph.D. Title of Diploma Thesis: PATIENTS' EXPERIENCES WITH ACUPUNCTURE TREATMENT III Background: Acupuncture becomes more popular in Czech Republic where study concerning patients' experiences and opinions with this treating method hasn't been carried out yet. Aim: To assess patients' experiences with acupuncture focusing on the patients' expected effect before, during and after treatment, on the potential change in expectations during treatment and on its potential effect on treatment outcomes, and on the evaluation of the truly perceived therapeutic effect. Methods: Using semistructured questionnaires, we led interviews with selected patients in the period from 19. 9. 2015 to 18. 5. 2016. Rewritten dialogues were afterwards coded in MAXQDA 12 and evaluated using the content analysis method. Results: Content analysis identified topics related to the expected and actual effect of acupuncture. It involved symptoms of migraine before and after treatment, treatment beliefs and expectations before, after and during treatment, recognition of therapeutic effect, adverse effects and benefit in patients' life. Patients had...
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Pharmacists' and Pharmacist Technicians' Attitudes toward Dietary Supplements
Janurová, Anna ; Pokladníková, Jitka (advisor) ; Marešová, Helena (referee)
PHARMACISTS' AND PHARMACIST TECHNICIANS' ATTITUDES TOWARD DIETARY SUPPLEMENTS Student: Anna Janurová Tutor: PharmDr. Jitka Pokladníková, Ph.D. Dept. of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University in Prague, Czech republic Background: Dietary supplements (DS) belong to the common commodity of the Czech pharmacies. However, attitudes of pharmacists and pharmacist technicians toward this issue have not been evaluated in the Czech Republic yet. Aim: To assess pharmacists' and pharmacist technicians' attitudes toward dietary supplements, DS awareness, beliefs about DS safety and efficacy, DS use and recommending DS to patients. Methods: This Diploma Thesis was based on research project - pilot survey "Complementary and Alternative Medicine: The Survey of Health Beliefs". The study was conducted through questionnaires. Data were collected in the period from 1.2.2009 to 31.5.2009 in selected Czech pharmacies. The data were processed in the computer programs MS Excel and PASW Statistics 18. Results: Questionnaires were completed by a total of 203 pharmacists and pharmacist technicians from pharmacies in the Czech Republic. Approximately 7 out of 10 pharmacists and pharmacist technicians regarded DS as safe, the same number as effective, more than three-quarters...
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Homeopathic Remedies in Emotional and Mental Disorders
Ispanopoulou, Nikoleta-Maria ; Marešová, Helena (advisor) ; Pokladníková, Jitka (referee)
HOMEOPATHIC REMEDIES IN MENTAL AND EMOTIONAL DISORDERS Student: Ispanopoulou, N.M. Tutor:Marešová, H. Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University in Prague, Czech Republic Background: This thesis was a challenge to give my attention to the medicaments that have not side effecst in the human treatment and to see the use of the raw and first materials that in consequence we find as substances in the pharmaceutical factory. The solution and response for me was in the Complementary Medicine and more specifically in the practice of homeopathy. The mental disturbances and the emotional imbalances are more available in there description and understanding and can from the other side influence the well being of the physical part and cause the illnesses. Aim: The study of both mental and emotional disorders and homeopathic remedies and the discovery of the way the one influence and benefits the other is the main purpose of this thesis. Methods: The method has to do with the detailed description of the properties that each homeopathic remedy posseses, according to the studies accomplished many years ago from many doctors and scientists of the Complementary Medicine. I have studied the raw materials, the length of action and the results, coming from a...
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Parents of the Pre-School Children and Vaccination II.
Klozová, Michaela ; Marešová, Helena (advisor) ; Pokladníková, Jitka (referee)
Student: Michaela Klozová Tutor: PharmDr. Helena Marešová Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University in Prague, Czech Republic Background: This thesis deals with the attitude of Czech parents of preschool children for vaccination. From this perspective, the issue of vaccination was not in the Czech Republic yet rated. The work provides an overview of basic knowledge about vaccination. Aim: The main objective of the study was to assess the attitudes of parents to vaccinate their children, to map their knowledge and experience with vaccination and their views on the legitimacy, efficacy and safety of vaccination in the Czech Republic. The operational objective was to determine what changes would be welcomed in this system. Finally, I was interested in whether parents let children vaccinated beyond the compulsory vaccination. Methods: A targeted survey of parents of preschool children, regardless of age and education. For data acquisition method was used questionnaires. The processing of the results was used a computer program Microsoft Office Excel 2007. The data were subjected to frequency analysis and confidence interval was calculated. The survey was conducted from September 2012 to November 2013 questionnaire was completed by 182 parents...
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