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Mechanisms of neurophatic pain states development
Přibáňová, Tereza ; Mrózková, Petra (advisor) ; Kuchtiak, Viktor (referee)
Pain is a natural warning signal that protects organisms from actual or potential damage. Upon the stimulation (burns, cuts, inflammation) of nerve endings - nociceptors, nerve signals are conducted via the peripheral nerve fibres into the spinal cord and brain, where they are then processed as painful, and a reaction occurs. Neuropathic pain, on the other hand, is pain caused by an injury or disease of the somatosensory system itself. Neuropathic pain has a substantial impact on the patient's quality of life and is likely to become more prevalent as the population grows older and the rates of diabetes and chemotherapy treatments rise. However, the treatment of neuropathic pain is often insufficient and comes with a number of undesirable side effects, which constitute a significant clinical problem. Research leading to the understanding of the molecular mechanisms of the development and maintenance of neuropathic pain is necessary in order to enhance the treatment of these states and to make it more effective. There is a myriad of factors responsible for the development of neuropathic pain, namely mechanisms which maintain the balance between inhibitory and excitatory somatosensory signalling, changes in the amount or composition of receptors and channels at the surface of the neuron, and most...
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Validization of Marlowe-Crowne Social Desirability Scale in the Czech Context
Přibáňová, Tereza ; Remr, Jiří (advisor) ; Hendl, Jan (referee)
Diploma thesis deals with the process of validization of Marlowe-Crowne social desirability scale in the Czech context. Despite the fact that social desirability represents an error, which can disrupt validity of obtained data, there is no official Czech version of Marlowe-Crowne scale that could be used in surveys. The aim of this thesis is to create Czech translation of the scale and test its functionality. The Marlowe-Crowne scale is introduced from a theoretical point of view firstly, is discussed its creation, characteristics, its importance in relation to social desirability, critics and problems and possibilities and difficulties of its use in the new context. Further are discussed different ways of translation of research instruments, which could help to preserve their purpose, and method of cognitive interviews as a way of testing of new or adapted research instruments. Modified parallel translation of three translators was used for creation of Czech version of Marlowe-Crowne scale. Cognitive interview, based mostly on verbal protocols, were used for testing of finally translated scale to find out, if scale is applicable in the Czech context without any problems. Interviews were conducted with sixteen respondents with different sociodemographic characteristics. Thesis concludes that scale...
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The Development of Orientalism and its Form in the Contemporary World
Přibáňová, Tereza ; Balon, Jan (advisor) ; Horák, Vít (referee)
The bachelor thesis deals with problems of orientalism, which is considered primarily in Edward Said's definition as a power discourse in which knowledge about the Orient is created. Even today, Westerners have to rely solely on mediated information about Orient, which can be quite misleading. The thesis first defines different meanings of orientalism and the categories of West and East. The thesis presents development of orientalism in its pre- modern and modern or academic form, including criticism of Said's concept. Critique of orientalism is currently included in postcolonial criticism, therefore there is a chapter on postcolonial criticism as well, which includes part about relationship of sociology to this issue. In conclusion is discussed occidentalism, which is often seen as the opposite of orientalism, but it isn't entirely accurate. Also is analyzed the contemporary form of orientalism, which is associated mainly with attitude of the Western world (mainly U.S.) to the Islamic countries.
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