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Current trends in electroconvulsive therapy
Opelka, Jakub ; Niederlová, Markéta (advisor) ; Kališová, Lucie (referee)
This bachelor thesis focuses on electroconvulsive therapy from a research and clinical perspective. Special emphasis is placed on cognitive impairment as one of the most serious side effects of electroconvulsive therapy. It also briefly summarizes the historical development and current good practice in electroconvulsive therapy. It presents several hypotheses on the mechanism of action of electroconvulsive therapy and briefly discusses the technical aspect of this treatment method. Future perspectives and new variants of convulsive methods are described with emphasis on Low Amplitude Seizure Therapy. The proposed research aims to compare the degree of cognitive impairment when using electroconvulsive therapy and its new variant Low Amplitude Seizure Therapy. A sub-objective is to map the profile of cognitive impairment with Low Amplitude Seizure Therapy alone, as no such research exists to date. A battery of cognitive tests consisting of the Montreal Cognitive Assessment, the MATRICS Consensus Cognitive Battery, and the Columbia University Autobigraphical Memory Interview - Short Form was constructed for research purposes. Keywords electroconvulsive therapy, Low Amplitude Seizure Therapy, cognitive function, retrograde amnesia, major depressive disorder, MATRICS Consensus Cognitive Battery
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