|
|
Využití hloubkového kypřiče při pěstování obilovin a řepky olejné v podniku Zemědělské služby Dynín, a.s.
KUBEŠ, Jan
This diploma thesis deals with deep cultivators which are used in companies of agricultural production. Theoretical part is focused on the history of soil proccessing, soil treatement and loosening machines which are being used today. That includes disc cultivators, tine cultivators, chisel cultivators, rod cultivators and machines with driven work gears. Practical part of theses includes comparison of chisel cultivator and plough doing tillage. The quality of keeping the depth invariable is being evaluated, as well as time-consuming nature, consumption of fuel and drain on resources.
|
|
|
Residential satisfaction of households in tenement houses in localities of Prague - the role of civic amenities
Bursa, Otakar ; Netrdová, Pavlína (advisor) ; Kubeš, Jan (referee)
Residential satisfaction belongs to important elements of human's satisfaction with life. It is created by the unique set of different components to which the accessibility and quality of civic amenities in a neighbourhood may also be included. Nevertheless, the importance of this factor used to be underestimated and the real connexion between residential satisfaction and the presence of civic amenities has not come out so far (Swindell, Kelly 2005). Therefore, the diploma thesis focuses on the qualitative- analytical research of residential satisfaction in two differently served Prague's localities with the aim to deepen the current knowledge of this issue. The results show that the presence of civic amenities in the neighbourhood has a significant effect in creating residential satisfaction which is comparable to the quality of housing and neighbourhood features. However, this relationship is partly influenced by the assigned importance of services' presence that especially varies according to the locality type (housing estate or suburban) and the position of household in a life cycle. Keywords: residential satisfaction, civic amenities, Prague, housing estate, suburb
|
|
|
Synthesis and in vitro evaluation of novel iron chelators based on salicylaldehyde isonicotinoyl hydrazone
Kubeš, Jan ; Roh, Jaroslav (advisor) ; Krátký, Martin (referee)
Charles University Faculty of Pharmacy in Hradec Králové Department of Organic and Bioorganic Chemistry Author: Jan Kubeš Supervisors: doc. PharmDr. Jaroslav Roh, PhD. PharmDr. Hana Jansová, PhD. Title of Diploma Thesis: Synthesis and in vitro evaluation of novel iron chelators based on salicylaldehyde isonicotinoyl hydrazone Iron ions (Fe) are required in many vital processes. However, this transition metal may also catalyze reactions which results in the formation of toxic reactive oxygen species (ROS), e.g. Haber- Weiss reaction producing highly toxic hydroxyl radicals. Salicylaldehyde isonicotinoyl hydrazone (SIH) is a tridental chelator selectively forming complexes with Fe ions. As a result of its low molecular weight and good lipophilicity, SIH can be administered orally. It readily enters the cells, effectively chelates the intracellular Fe ions, and is therefore able to very efficiently inhibit the Fe dependent processes, such as production of ROS, but also the synthesis of some proteins and enzymes and the processes they regulate (e.g., cellular growth and proliferation). In this work we focused on the design, synthesis and in vitro evaluation of novel SIH analogues, in particular the thio analogue of SIH (thioSIH, A), analogues derived from (di)hydroxybenzophenone (B) and...
|
|
|
The possibilities and problems of rural brownfields revitalization in the Region of South Bohemia.
Marhounová, Simona ; Perlín, Radim (advisor) ; Kubeš, Jan (referee)
The thesis deals with the problematic of revitalisation related to brownfields in the selected administrative units of South Bohemian region. The case territory includes the municipality with extended powers of České Budějovice and the municipality with extended powers of Prachatice. Those case territories differ in few elements, mainly in regards with vertical and horizontal geographic position. The purpose of the thesis is to analyse how the rural brownfields are utilised, the thesis also focuses on the way stakeholders cooperate with each other during the revitalization of the brownfields. The methodology of the thesis is based on brownfields evaluation in the above mentioned territory, followed by a detailed analysis of the recovery issues by interviewing local stakeholders. The interviews were held with representatives of privat and public sector in the selected municipalities, where the brownfields were located. After evaluating the results for individual municipalities with extended powers, a comparison was done based on witch some regularities were found. The results of the research confirmed the hypotheses about the differences in interconnections between public and privat sector in different municipalities with extended powers. The hypothesis, assuming differences in the way of...
|
|
| |
|
|
Regional defferentiation of long-term land-use changes in the Czech Republic
Štych, Přemysl ; Bičík, Ivan (advisor) ; Kubeš, Jan (referee) ; Kolejka, Jaromír (referee)
9 9 E U:E 6 ř.=.. E-JEE=> šE:€ g€* ášB iš č=íEšag;l3 ;E š*EEE E$E 8E: šgĚ:É..*€€ É;:ÉE Ě8EÉĚE€EE iHI EĚ Ěpř;ĚiÉĚ€uiÍi +E štĚĚ€;ĚgEe*{g EE š$ e ; i : * Ť Ě E E ! E o žE šÉ::t*š*É€Í;-řéE š*EEĚgEĚ*Ěat#* Ť$ Š*c.i ďi+,d -- š'.-. €| .9 oao o9-oil) 9(B *o >' (Fi roÉ "BE5ř>'rěao !- oo 7aó o E= o.r 0.l ýo+a F^ o.o Yoey^ (HOYa orA o (€'ii ! >,o (!= 4 >co0) .ř b.Etr o-> trYa) o\wť X E.E.š.E p .aXX -'ář g.Ěɚ̀řs €:ÉĚ ĚĚEEiB;Eř €;:5!Ě:* Ě;6* šig*;:ěťÉ €áiEřÍšÉ ii;ť:*€€ís;;i 3ÉťiĚÉš.ĚÍEřó E;ť*+t:;É ÉeĚ:!'iiE':.ě= EiE**:=šEc Eš!eEE:EtĚei;ĚsĚ;s!gÍ;á 't ÉĚť;:ĚfíÉĚř:i:řEE'EEĚí;ÍE Ě gĚÉ [EgĚĚE ĚĚEiE ÉEEšEĚěEĚE
|
|
|
Changing spatial pattern of land use in the Czech Republic and its driving forces
Kabrda, Jan ; Bičík, Ivan (advisor) ; Kubeš, Jan (referee) ; Spišiak, Peter (referee)
Jan KABRDA: Changing spatial pattern of land use in the Czech Republic and its driving forces The main objective of my.dissertation thesis is to analyse changes of spatial pattern of land use in the Czech Republic since the mid-19'n century. My secondary aim is to discuss advantages and limits of various methods that can be used for this research. The text is divided into two main sections. The first one includes an overyiew of literature on the given issue. The second one comments six attached articles that constitute the main body of the thesis, representing main results of my research. The first section of my thesis consists of three chapters. In the first one I discuss the term,,land use" itself; importance and practical applicability of its research; and theoretical approaches used throughout the world to explain patterns and changes of land use, and to create schemes for its;;search. Chapter Two includes an overyiew of methods and data sources used in land use research, especial|y of quantitativ" ón.,, in the whole world in general, and in Central Europe in particular. In the third chapter I summarize the main processes of land use changes - of current changes at global level, and of changes during last two centuries within the Central European context. The six attached articles represent...
|
|
|
Residential mobility and fulfilling the ideas of cohousing in the everyday life of inhabitants: Case study of the Klidná project
Horňáková, Marie ; Jíchová, Jana (advisor) ; Kubeš, Jan (referee)
The thesis deals with cohousing; a concept of living based on common spaces and shared facilities. In the first phase, the aim is to provide a summary of the development of cohousing and other similar forms of housing in the world and also in Czechia. The second phase focuses on a concrete by cohousing inspired residential project located in the inner city of Prague. In the work it appears under the name Klidná. The second phase aims to find out what led the communication partners to choose Klidná as a new place of residence, how important role did the specific aspects based on cohousing played in the decision-making process and finally how are the ideas of this concept being fulfilled in everyday life of the inhabitants. The research is of a qualitative nature and the main method of data collection is realization of deep semi-structured interviews, which are subsequently evaluated on the basis of theoretical thematic analysis. Based on the study, none of the communication partners chose Klidná because of the concept of cohousing. They perceived the existence of common areas, small scale of the project or its spatial layout rather as a pleasant bonus. Fulfilling ideas of the concept in everyday life of the informants corresponds with the nature of the project and the context in which it was...
|
|
|
An alternative view on Czech banking sector's riskiness
Kubeš, Jan ; Teplý, Petr (advisor) ; Troch, Tomáš (referee)
Riskiness of Czech banking sector is subject of interest of this thesis. Since the beginning of 21st century, there is moderately growing number of banks and their overall profitability expressed in absolute values is increasing. Ratio of non-performing loans to total loans is also displaying optimistic values. Four indicators of riskiness are studied through data about Czech banks from 2008 to 2015. These indicators are: z-score, leverage ratio, RWA density and ratio of non- performing loans to total loans. Rather low correlations among these indicators are found, the highest correlation (0,670) is between leverage ratio and RWA density, on the other hand the lowest one (0,093) is between z-score and NPL ratio. In aggregate form are three of the indicators displaying stable trend to lower riskiness in 2008-2015 period, the same can be stated about NPL ratio in 2010-2015 period. Then is regression analysis employing fixed effects estimation and random effects estimation used, with the aim to identify determinants of the four indicators. Size of banks expressed in logarithm of total assets is significant in only one model with RWA density on the place of dependent variable. This significance is at 10 per cent level and corresponding coefficient is negative. In contrary, growth of assets and dummy...
|
|
|
Transport mechanisms of secondary metabolites across membranes of plant cells
Kubeš, Jan ; Tůmová, Lenka (advisor) ; Babula, Petr (referee) ; Obložinský, Marek (referee)
Faculty of Pharmacy in Hradec Králové, Charles University Department of pharmacognosy Candidate: Mgr. Jan Kubeš Supervisor: PharmDr. Lenka Tůmová, CSc. Title of Doctoral thesis: Transport mechanisms of secondary metabolites across membranes of plant cells An attention was focused on the metabolism of isoflavones in recent years, including their transport within plants and cultures in vitro. A research is focused on the transport mechanism identification across cell or vacuolar membrane. There are localized different transporters as or the transport of some metabolites can take place through membrane vesicules. The release of five isoflavones (genistin, genistein, biochanin A, daidzein and formononetin) into nutrient medium was observed in suspension culture of Genista tinctoria L and Trifolium pratense L. These cultures were treated with NH4VO3 solutions (1 a 10 M concentration) when isoflavon content in medium was higher after 24 hours. This increased volume of isoflavones was supressed by different transport mechanism inhibitors. The transport of isoflavones in T. pratense was influenced by ABC inhibitors from MRP subfamily, but genistein concentration in medium was lower after treatment with MDR subfamily inhibitors. Brefeldin A, which blocks vesicular transport, also decreased concentration of...
|
guest ::
RSS feed.