|
|
How to Prepare a Stage Game for the Integrated Group of Children
Kleinová, Jana ; Ortová, Marie (advisor) ; Růžička, Vít (referee)
In this seminar I give examples of how to prepare a summer camp for integrated groups of children. There are three parts. In the first part you can find general information on how to prepare a summer camp, more specific information being in the section on specialized literature. The second part deals with the special needs of handicapped children, how to build a suitable environment to meet their physical and mental development needs, which will allow for growth and expression, as well as for non- handicapped children, and allow for friendship and positive interaction between handicapped and non- handicapped children. In the third and main part of this seminar, I describe, day by day, a multi-stage game for integrated groups of children. In this game handicapped children can show their abilities, knowledge, and are given the chance to gain self-confidence. To children without handicaps the game brings knowledge of handicapped children's lives, and helps to develop understanding. Also, it focuses on the physical development of the children, and helps build awareness of life in their country. This helps to decrease the distance between handicapped people and the rest of society. Public attitudes towards people with handicaps are full of misunderstanding and apathy. The purpose of integrated summer camp is...
|
|
|
Development of a UHPLC-MS/MS method suitable for the determination of cabozantinib in blood serum
Kleinová, Jana ; Kozlík, Petr (advisor) ; Hraníček, Jakub (referee)
The aim of this Bachelor thesis was to develop a UHPLC-MS/MS method for the determination of Cabozantinib in blood serum. This method was used to monitor the release of the active substance in a model organism - the rat. First, the mass spectrometer setup was optimized, where MRM transitions for Cabozantinib and isotope-labelled Cabozantinib-D4 were found. For Cabozantinib, an MRM transition of 502.2 → 323.1 was found with optimal energy levels of Q1 = -26.0 V, CE = -40.0 V and Q2 = -22.0 V. For Cabozantinib-D4, the MRM transition of 506.2 → 327.0 was found with optimal energy levels being Q1 = -26.0 V, CE = -39.0 V and Q2 = -22 V. The method setup parameters were as follows: The chromatography column used was a Poroshell 120 EC-C18, 2.1x50 mm, 1.9 um, (Agilent Technologies). The mobile phase consisted of acetonitrile (B) and formic acid (A), the flow rate of the mobile phase was 0.350 ml/min, the analysis time was 5.5 min and the injection volume was 1 μl at gradient elution (time: 0; 0.5; 2.0; 3.0; 3.5; 4.0; 5.5 min, B: 10; 10; 60; 100; 10; 10 %). The method was linear (weighted regression 1/x2 ) with a regression coefficient equal to 0.9978, showing an excellent linearity of the method. The precision (relative standard deviation) of the method was within 14 %. The accuracy (relative error) was...
|
|
|
Studium těkavých látek v pivovarských surovinách, v meziproduktech při výrobě piva a v pivu
Kleinová, Jana
Gas chromatography with mass spektrometry and gas chromatography with flame ionization detector were used for the determination of volatile compounds in raw material for beer production, in intermediate products and in beer. Isolation of compounds with low boiling point was optimized using purge and trap analysis, solid phase microextraction, liquid extraction, and static headspace. Solid phase microextraction was proved to be the most useful for determination of Maillard reaction products that are formed during kilning and roasting of malt, hop essential oils and volatile substances produced by fermentation. The ratio of hop essentials oils with lower boiling point (alfa-humulene, beta-farnesene and beta-caryophyllene) decrease during wort boiling. Maillard reaction products are formed during wort boiling, although the content of 3-methylbutanal and maltol is reduced by evaporation. Higher concentration of volatile substances contained top-fermented beer except 3-methyl-1-butanol. The Dudák Premium proved the best results of the analyzed bottled beers. The Stella Artois contained the lowest concentration of volatile compounds.
|
|
|
How to Prepare a Stage Game for the Integrated Group of Children
Kleinová, Jana ; Ortová, Marie (advisor) ; Růžička, Vít (referee)
In this seminar I give examples of how to prepare a summer camp for integrated groups of children. There are three parts. In the first part you can find general information on how to prepare a summer camp, more specific information being in the section on specialized literature. The second part deals with the special needs of handicapped children, how to build a suitable environment to meet their physical and mental development needs, which will allow for growth and expression, as well as for non- handicapped children, and allow for friendship and positive interaction between handicapped and non- handicapped children. In the third and main part of this seminar, I describe, day by day, a multi-stage game for integrated groups of children. In this game handicapped children can show their abilities, knowledge, and are given the chance to gain self-confidence. To children without handicaps the game brings knowledge of handicapped children's lives, and helps to develop understanding. Also, it focuses on the physical development of the children, and helps build awareness of life in their country. This helps to decrease the distance between handicapped people and the rest of society. Public attitudes towards people with handicaps are full of misunderstanding and apathy. The purpose of integrated summer camp is...
|
|
|
People with basic education in the labor market in the region Tábor
KLEINOVÁ, Jana
In my thesis I focus my attention on problem people with primary education on labour market in region Tábor. The aim of the work is evaluate the unemployment of people with basic education on the labour market in region Tábor and look for the resolution of this issue. Theoretical part of the thesis is focusing on the labour market, unemployment and education. These topics are closely connected. We are describing the region Tábor, important firms, and also projects of the European Union, which can increase the employment on the labour market. The research is doing by the quantitative research. We are using questionnaire inquiry and statistical assessment. We focus on two different categories of the job seekers, people with elementary education and higher education (secondary education without and with graduation, higher technical education, university education). It was addressed 84 job seekers who are in evidence of the employment office in Tábor. We made interviews with 10 expert advisers of the employment office in Tábor and we also interviewed 3 representatives of villages Jistebnice, Planá nad Lužnicí and Sezimovo Ústí over the phone. The results of the interviews are processing and presenting in tables. In chapter 5 under the name discussion is afterwards made detailed analysis. I consider this bachelor's thesis very actual. Results of this work could help employees of the employment office in Tábor, Asylum building for woman and mothers with children in Tábor, but at the same time also various firms in areas at Tábor and give them better information and orientation in this theme.
|
|
|
Studium těkavých látek v pivovarských surovinách, v meziproduktech při výrobě piva a v pivu
Kleinová, Jana
Gas chromatography with mass spektrometry and gas chromatography with flame ionization detector were used for the determination of volatile compounds in raw material for beer production, in intermediate products and in beer. Isolation of compounds with low boiling point was optimized using purge and trap analysis, solid phase microextraction, liquid extraction, and static headspace. Solid phase microextraction was proved to be the most useful for determination of Maillard reaction products that are formed during kilning and roasting of malt, hop essential oils and volatile substances produced by fermentation. The ratio of hop essentials oils with lower boiling point (alfa-humulene, beta-farnesene and beta-caryophyllene) decrease during wort boiling. Maillard reaction products are formed during wort boiling, although the content of 3-methylbutanal and maltol is reduced by evaporation. Higher concentration of volatile substances contained top-fermented beer except 3-methyl-1-butanol. The Dudák Premium proved the best results of the analyzed bottled beers. The Stella Artois contained the lowest concentration of volatile compounds.
|
|
| |
|
| |
|
| |
guest ::
RSS feed.