National Repository of Grey Literature 4 records found  Search took 0.00 seconds. 
Enantioselective synthesis of fluorinated organic compounds using iminium and enamine catalysis
Hejnová, Monika ; Veselý, Jan (advisor) ; Smrček, Stanislav (referee)
This diploma thesis deals with the scope of organocatalytic concept for the preparation of enantiomerically pure organic compounds, containing fluorine atom. Our attention was focused on the use of easily available α,β-unsaturated aldehydes and ketones as starting materials and commercially available secondary amines as catalysts. The first part of the work is dedicated to the enantioselective cyclization reaction of hydrazone (24) with cyclohex-2-enone (25). The second part describes a study of enantioselective nucleophilic addition of diethyl 2-fluoromalonate (31a) to α,β-unsaturated aldehydes (30) via enamine activation.
Enantioselective synthesis of fluorinated organic compounds using iminium and enamine catalysis
Hejnová, Monika ; Veselý, Jan (advisor) ; Smrček, Stanislav (referee)
This diploma thesis deals with the scope of organocatalytic concept for the preparation of enantiomerically pure organic compounds, containing fluorine atom. Our attention was focused on the use of easily available α,β-unsaturated aldehydes and ketones as starting materials and commercially available secondary amines as catalysts. The first part of the work is dedicated to the enantioselective cyclization reaction of hydrazone (24) with cyclohex-2-enone (25). The second part describes a study of enantioselective nucleophilic addition of diethyl 2-fluoromalonate (31a) to α,β-unsaturated aldehydes (30) via enamine activation.

See also: similar author names
2 HEJNOVÁ, Martina
4 HEJNOVÁ, Michaela
2 HEJNOVÁ, Miroslava
3 Hejnová, Marie
4 Hejnová, Michaela
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