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Virtual laboratory for simulation of biological processes on membranes
Beneš, Martin ; Bílý, Tomáš (advisor) ; Hoksza, David (referee)
The purpose of this thesis is the creation of a virtual computer laboratory, where it will be possible to simulate and analyze the behavior on the biological cell membrane. The membrane and its surroundings are described as a hex-net with other chemicals and components that interact with each other. Depending on this distribution, it is possible to observe well-known membrane phenomena such as the amplification of the action potential. The simulation itself should show, that for the basic membrane-activity modeling, you only need a few basic laws of physics and chemistry. Powered by TCPDF (www.tcpdf.org)
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Scramble simulator
Šindelář, Ondřej ; Bílý, Tomáš (advisor) ; Hladík, Milan (referee)
The work aims to implement a graphic game simulating motocross ride. The player controls a motorbike rider and tries to get him from start to nish as quickly as possible. He has to collect checkpoints laid out along a track without striking his head against the ground. Tracks composed of polygons can be created and edited in included track editor. In addition to single-player game there are also four di erent multiplayer game modes to be played on one or mulitple computers. It is possibile to replay previously saved ride recordings. The scene is displayed as a side view and is rendered using OpenGL library. The program is implemented on Win32 platform.
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Mouse Gestures
Dzurenko, Miroslav ; Bílý, Tomáš (advisor) ; Karásek, Michal (referee)
Computer mouse was invented more than forty years ago, but its real potential is not even used at present. Application Just Gestures extends mouse possibility with "mouse gestures" - gestures which are created in combination with mouse clicks and movements. This trajectory is recognized and executes specific command for any application or operating system, what makes work easier and faster. The aim of this work is to create an application for Microsoft Windows system based on neural network recognition. In regards to our specification, it is necessary to divide problem in to three basic parts - retrieving and processing mouse actions, learning, recognition of gestures and executing the adequate command.
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Rozhraní pro interakci vituálních bio-laboratoří
Mikula, Tomáš ; Hedrlín, Zdeněk (advisor) ; Bílý, Tomáš (referee)
Virtual bio-laboratories are programs for performing virtual experiments. They are based on the idea that mathematical and computer science methods can prove successful in biology and medicine, too. The applicability of this approach is gaining more and more recognition in the last years. Current virtual bio-laboratories are standalone programs, each aimed at simulating one tissue or one biological process. There is a growing need for a unifying interface that would allow to design laboratories that can interoperate with each other while being developed independently. In this work we design such an interface and implement a working prototype. The interface will make as few assumptions about the nature of particular bio-laboratories as possible. Diverse laboratories can then "talk" together through their common subset of supported interactions. This greatly enhances the code reusability between experiments - libraries of already developed laboratories and defined interactions are used to set up your experiment and you only implement the missing parts. We implement a couple of basic laboratories and interactions to prove the concept and to help the developers quickly start with their first virtual experiments.
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3D elektronová tomografie a korelativní mikroskopie
BÍLÝ, Tomáš
Electron tomography allows visualization of objects in a form of reconstructed 3D virtual volumes with resolution power of electron microscopy. The thesis is focused primarily on biological applications of electron tomography applied on tilt series images acquired in transmission electron microscope at room temperature. Specifically, the interaction of tick-borne encephalitis virus with neural cells and 3D ultrastructure of the central electron-dense part of the flagellum 9 + 1 (Caryophyllaeides fennica) were investigated. Finally, electron tomography was combined and correlated with atomic force microscopy to allow repetitive examination of ultrathin sections on electron microscopy grids.
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Data classification from posturographic measurements
Tesař, Zdeněk ; Bílý, Tomáš (advisor) ; Neruda, Roman (referee)
This bachelor's thesis describes the design and implementation of a C# application for classifying disorders of patients' balance systems using data acquired from posturographic measurements. The application was created by the paper's author on the basis of a collaborative effort with experts from the 2nd Faculty of Medicine at Charles University in Prague, which was also the site of its first experimental use for testing and research purposes.
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Virtual laboratory for simulation of biological processes on membranes
Beneš, Martin ; Bílý, Tomáš (advisor) ; Hoksza, David (referee)
The purpose of this thesis is the creation of a virtual computer laboratory, where it will be possible to simulate and analyze the behavior on the biological cell membrane. The membrane and its surroundings are described as a hex-net with other chemicals and components that interact with each other. Depending on this distribution, it is possible to observe well-known membrane phenomena such as the amplification of the action potential. The simulation itself should show, that for the basic membrane-activity modeling, you only need a few basic laws of physics and chemistry. Powered by TCPDF (www.tcpdf.org)
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Virtual laboratory for simulation of biological processes on membranes
Beneš, Martin ; Bílý, Tomáš (advisor) ; Hoksza, David (referee)
The purpose of this thesis is the creation of a virtual computer laboratory, where it will be possible to simulate and analyze the behavior on the biological cell membrane. The membrane and its surroundings are described as a hex-net with other chemicals and components that interact with each other. Depending on this distribution, it is possible to observe well-known membrane phenomena such as the amplification of the action potential. The simulation itself should show, that for the basic membrane-activity modeling, you only need a few basic laws of physics and chemistry.
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Image comparison using eye movement simulation
Veľk, Miroslav ; Bálek, Martin (advisor) ; Bílý, Tomáš (referee)
In the present work we study the biologically plausible and psychologically motivated model of human visual attention and explain the importance of similar models. We propose and implement methods to find salient locations in the image. We give detailed instructions on creating saliency maps, which contain information about saliency of every location in the explored scene. Using this maps we simulate shifts of visual attention (eye movement). A simulated scanpath representing this shifts is created and then analyzed. We especially focus on comparison of different scanpaths by different features. Finally practical use of our model is outlined.
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