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National Repository of Grey Literature

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GlcNAc8-dendrimer as a ligand of NKR-P1A receptor in effector-target cell interaction and G-protein signaling Svoboda, Jan ; Kuldová, Markéta ; Huliková, Katarína ; Miller, R. G. ; Fišerová, Anna GlcNAc8 glycodendrimer is a specific ligand of rat NKR-P1A receptor isoform. In effector cells triggers the Gq/11 protein-mediated signaling pathway, and induces subsequent changes in tumor microenvironment Detailed record

Multivalentní glykokonjugáty ve studiu interakce lektinových receptorů NK/NKT buněk Vannucci, Luca ; Pospíšil, Miloslav ; Rossmann, Pavel ; Chernyavskiy, Oleksandr ; Kubínová, Lucie ; Křen, Vladimír ; Luptovcová, Martina ; Svoboda, Jan ; Kuldová, Markéta ; Bezouška, Karel ; Fišerová, Anna The events following the administration of GN8 in vitro, in vivo and ex vivo, lead to increased expression of CD69. The CD69-dependent IFNg production is modulated by co-activation of NKG2D and Ly49 receptors. Glycodendrimers can assist the dissection of activation network of NK/NKT cell lectin-like receptors in rat and murine models Detailed record

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