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National Repository of Grey Literature

63 records found  33 - 42  jump to record:

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	Polymerní konjugát doxorubicinu na bázi HPMA, působící ve shodě s protinádorovou imunitou nositele Šírová, Milada ; Rossmann, Pavel ; Mrkvan, Tomáš ; Strohalm, Jiří ; Šubr, Vladimír ; Plocová, Daniela ; Ulbrich, Karel ; Říhová, Blanka Polymeric conjugate Dox-HPMA-HuIg directly targets the tumour due to the EPR effect, it is not detrimental towards the immune system of the host, and acts in concert with the anti-tumour immune responses Detailed record
	Glykosylace povrchové membrány EL-4 buněk: vliv volného nebo N-(2-hydroxypropyl)methacrylamide (HPMA) vázaného doxorubicinu Kovář, Lubomír ; Etrych, Tomáš ; Šubr, Vladimír ; Strohalm, Jiří ; Sklenář, Jan ; Chytil, Petr ; Ulbrich, Karel ; Říhová, Blanka In those experimenst we studied the possible impace of CD43 as highly glycosylated molecule in cells exposed to free doxorubicin (Dox) or to conjugates consisting of HPMA copolymer backbone to which the drug is conjugated via enzymatically (PK1 conjugate) or pH sensitive, hydrolytically cleavable bond (hydrazone conjugate, HYD). Detailed record
	Protilátka anti-DR5 vázaná na HPMA: nový přístup k imunochemoterapii nádorů Říhová, Blanka ; Hovorka, Ondřej ; Kopečková, P. ; Kopeček, J. Dimerized antibodies anti-DR5 bound to the synthetic polymer based on HPMA, effectively induce apoptosis of the tumor cells that express TRAIL on their surface. At the same time, the tumor cells are also targeted by cytotoxic drug +doxorubicin bound to the HPMA polymeric conjugate Detailed record
	Imunostimulační a imunoprotektivní vlastnosti makromolekulárních protinádorových léčiv Říhová, Blanka ; Strohalm, Jiří ; Šírová, Milada ; Etrych, Tomáš ; Mrkvan, Tomáš ; Šubr, Vladimír ; Plocová, Daniela ; Kovář, Marek ; Ulbrich, Karel Polymeric conjugates of doxorubicin, non-targeted or antibody targeted cure mice from experimental EL4 T cell lymphoma and induce specific, systemic long-lasting anti/tumor resistance Detailed record
	Indukce efektivní protinádorové imunity při léčbě směrovaným konjugátem na bázi poly(HPMA) obsahujícím doxorubicin Kovář, Marek ; Tomala, Jakub ; Mrkvan, Tomáš ; Etrych, Tomáš ; Strohalm, Jiří ; Ulbrich, Karel ; Říhová, Blanka Thus, treatment with B1 mAb-targeted conjugates is able to completely cured BCL 1 bearing mice and most importantly, break immunoescaping mechanisms of BCL1 cells Detailed record
	Nepřímá kvantifikace jaderné akumulace doxorubicinu Hovorka, Ondřej ; Eckschlager, T. ; Strohalm, Jiří ; Ulbrich, Karel ; Říhová, Blanka This method increased the detection sensitivity more than ten times and allowed us to quantify doxorubicin cleaved from the conjugates and intercalated into nuclear DNA Detailed record
	Směrovaná polymerní protinádorová léčiva na bázi HPMA v terapii HNSCC Bouček, Jan ; Betka, J. ; Strohalm, Jiří ; Plocová, Daniela ; Šubr, Vladimír ; Mrkvan, Tomáš ; Ulbrich, Karel ; Říhová, Blanka Targeted conjugates are promising novel drugs and especially anti-EGFR targeted conjugates seem to be a perspective modality in treating HNSCC or other cancers over-expressing EGFR receptor Detailed record
	Vliv N-(2-hydroxypropyl)methacrylamidového kopolymeru obsahujícího doxorubicin na mitogenem aktivované protein kinázové signalizační dráhy Kovář, Lubomír ; Strohalm, Jiří ; Chytil, Petr ; Plocová, Daniela ; Mrkvan, Tomáš ; Ulbrich, Karel ; Říhová, Blanka We demonstrated that the mitogen-activated protein kinases (MAPKs) play a crucial role in cancer cell death and survival, however their role seems to be indirect. We confirmed the previously published results showing that different intracellular processes are underway in cancer cells treated with Dox.HCl compared to those incubated with HPMA conjugates Detailed record
	In vitro účinnost polymerních konjugátů směrovaných mAb anti-EGFR nebo lidským polyklonálním IgG Bouček, Jan ; Betka, J. ; Strohalm, Jiří ; Plocová, Daniela ; Šubr, Vladimír ; Mrkvan, Tomáš ; Ulbrich, Karel ; Říhová, Blanka Targered prodrugs are promising novel agents and especially anti-EGFR targered conjugates seem to be a perspective modality in treating HNSCC Detailed record
	Směrovaná polymerní léčiva pro terapii nádorových onemocnění Kovář, Marek ; Mrkvan, Tomáš ; Šírová, Milada ; Strohalm, Jiří ; Šubr, Vladimír ; Etrych, Tomáš ; Ulbrich, Karel ; Říhová, Blanka We have presented data on development of polymer-bound cytostatic drugs and their therapeutic efficacy in selected tumor models Detailed record

National Repository of Grey Literature : 63 records found   33 - 42  jump to record:

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15	Říhová, Barbora

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