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The influence of socio-geographical exposure and other factors on the extensification processes of land use
Janoušek, Zbyněk ; Bičík, Ivan (advisor) ; Feranec, Ján (referee) ; Novotná, Marie (referee)
The main topic of the dissertation thesis is the evaluation of the influence of socio- geographical exposure and other factors (natural: altitude, inclination of slopes, productivity of land) on the extensification processes of the land use in Czechia in the period of more than 160 years, 1845-2010. Emphasis is also placed on the associated losses of agricultural and arable land, given that afforestation and increase of grassland took place essentially at the expense of that land. The main data source is the "Database of long-term land use changes in Czechia (1845-2010)", LUCC Czechia, based on cadastral records. It is a detailed monitoring which covers almost 9,000 so-called stable territorial units. Both the extensification processes and the overall intensity of land use (using the coefficient of ecological importance) are evaluated. Given that most of the Czechia's territory is still used as agricultural land, the thesis also includes an overview of the evolution of the selected agricultural intensity indicators. Attention is likewise paid to the wider context of land use changes at the European level. The essential part of the thesis is to build models of socio-geographical exposure of Czechia, which are comparable with the data on land use in the time horizons of 1845, 1896, 1948, 1990 and...
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Political and geographical aspects of Pilsen's city development
Černík, Vojtěch ; Tomeš, Jiří (advisor) ; Janoušek, Zbyněk (referee)
The aim of this bachelor thesis is to briefly describe the city of Pilsen in terms of urbanism and to evaluate the progression of the city since the political changes in 1989. The first part of the text is based on the discription of the city and its main problems, the functional structure of the city and the key periods in the progression of the city. The second part of the thesis is dedicated to a comparison of the city's spatial plans of 1995 and 2005 and the analysis of the strategic plan. This analysis demonstrates the evolution of the city and compares the original expectations with the current situation. In the end the whole analysis is integretated into the political and economical context. The main point of this part is the intorduction of some controversial projects that makes the Pilsen's public to be more interested in the city problems. This conflict leads to increasing the interest of the public space by common people in Pilsen.
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Evaluation of Long-Term Land Use Changes in Czechia at Different Scale Levels
Janoušek, Zbyněk ; Bičík, Ivan (advisor) ; Kupková, Lucie (referee)
Long-term evolution of nature-society interactions can be studied by using data of land use change. In the thesis is used a detailed statistical database of Czechia (developed at Charles University in Prague, Faculty of Science). The database allows monitoring changes of eight categories of land use in the period 1845-2000. Attention is devoted to the growing differentiation of land use at different scale levels, the thesis is concentrated on functional specialization of czech regions. Deepening division of labour between regions is reflected by increasing territorial concentration of land use. This process is monitored by using three methods. Ternary plots present an overview of the differentiation trends of land use. Spatial autocorrelation methods present the general development and specific areas of functional specialization in Czechia. A review by territorial heterogeneity rate provides a detailed look at the change of territorial concentration of land use. The thesis operates with three territorial classifications (hydrological, geomorphological and administrative) at two regional levels and the level of Czechia. Results are interpreted using the driving forces (such as technological development, economics, historical events, society). The final part of the thesis compares the development of...
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Industrial Geography Transformation as a Consequence of the Industrial Revolution: Example of the Brewing Industry In Prague, 1869-1939
Sobota, Tomáš ; Hasman, Jiří (advisor) ; Janoušek, Zbyněk (referee)
Tomáš Sobota: Industrial Geography Transformation as a Consequence of the Industrial Revolution: Example of the Brewing Industry In Prague, 1869-1939 Abstract The aim of this bachelor thesis is to describe the general factors which influenced the development of the brewing industry in Prague between the years 1869 and 1939. A description and definition of factors influencing the brewing industry during that time period is in the theoretical part of this thesis. The general factors include the formation of cartels, redevelopment of the centre of Prague, the First World War and the Great Depression. This thesis also includes a description of the impact of breweries (founded after the year 1869) on other brewing companies. The empirical part of this thesis describes changes of spatial distribution of bier production during the period of interest. This is done by thematic maps and diagrams related to the issue. Keywords: Prague - brewing industry - industry - industrial revolution - geography
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Synthesis of new carborane and metallacarborane bulding blocks appliable in design of biologically active compounds
Nekvinda, Jan ; Grüner, Bohumír (advisor) ; Janoušek, Zbyněk (referee)
Compounds with carboxylic and amidic functions belong to basic structural blocks, which are used for construction of functional molecules in organic, organometallic and also in carborane chemistry. However, considering cobalt bis(dicarbollide)(1-) ion, the synthetic ways to these derivatives have been virtually unknown. A published procedure on lithiation in THF and reaction with CO2 leading to mono- and dicarboxylic acids had failed in our hands. Nevertheless, a detailed revision of the experimental conditions provided finally good yields of mixture of both acids, which could be separated by chromatography and crystallization, and compound of general formulation [(1-HOOC-1,2-C2B9H10)(1',2'-C2B9H10)-3,3'-Co(III)]- and stereoisomeric mixture of [(HOOC)2-(1,2-C2B9H10)2-3,3'-Co(III)]- were characterized for the first time by combination of NMR, MS and HPLC. Also, the carboxylic acid derivatives with methylene and ethylene connectors of the general formula [(1-HOOC-(CH2)n-1,2- C2B9H10)(1',2'-C2B9H10)-3,3'-Co(III)]- were prepared by lithiation of Cs1 in DME at low temperatures followed by reaction with BrCH2COOEt and subsequent hydrolysis of the resulting ester or by oxidation of the respective propylhydroxy derivative. The acids were converted to reactive p-nitrophenyl esters...
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Carborane structural blocks in medicinal chemistry
Nekvinda, Jan ; Grüner, Bohumír (advisor) ; Machara, Aleš (referee) ; Janoušek, Zbyněk (referee)
This work deals with carborane and metallacarborane clusters, in terms of their fundamental chemistry and complexation with cyclodextrins, and in the context of emerging pharmacophores applicable in medicinal chemistry. Arguably, the most important part of this work is the preparation of cobalt bis(dicarbollide) sulfamide derivatives. The sulfamido group is attached to the metallacarborane carbon vertex by an alkyl chain that may be modified in its length. This was accomplished by, firstly, the abstraction of the acidic hydrogen, located on the {CH}-vertex from the metallacarborane, by reaction with lithium base, followed by, secondly, reaction with electrophilic agents (PFA, oxirane and oxetane), which leads to a cascade of reactions to give the desired sulfamide derivatives. These compounds were then tested by collaborators in other institutes for in vitro and in vivo activity towards Carbonic Anhydrase IX (CA IX), which is an enzyme associated with tumour growth. In vivo tests on mice have shown that these types of substances are able to effectively reduce tumour size by 30%. The synthetic research continued with the preparation of sulfonamide compounds of the isomers of the carborane series. The reactions began exclusively with propylhydroxy carborane starting materials, which provide optimum...
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The influence of socio-geographical exposure and other factors on the extensification processes of land use
Janoušek, Zbyněk
The main topic of the dissertation thesis is the evaluation of the influence of socio- geographical exposure and other factors (natural: altitude, inclination of slopes, productivity of land) on the extensification processes of the land use in Czechia in the period of more than 160 years, 1845-2010. Emphasis is also placed on the associated losses of agricultural and arable land, given that afforestation and increase of grassland took place essentially at the expense of that land. The main data source is the "Database of long-term land use changes in Czechia (1845-2010)", LUCC Czechia, based on cadastral records. It is a detailed monitoring which covers almost 9,000 so-called stable territorial units. Both the extensification processes and the overall intensity of land use (using the coefficient of ecological importance) are evaluated. Given that most of the Czechia's territory is still used as agricultural land, the thesis also includes an overview of the evolution of the selected agricultural intensity indicators. Attention is likewise paid to the wider context of land use changes at the European level. The essential part of the thesis is to build models of socio-geographical exposure of Czechia, which are comparable with the data on land use in the time horizons of 1845, 1896, 1948, 1990 and...
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The influence of socio-geographical exposure and other factors on the extensification processes of land use
Janoušek, Zbyněk
The main topic of the dissertation thesis is the evaluation of the influence of socio- geographical exposure and other factors (natural: altitude, inclination of slopes, productivity of land) on the extensification processes of the land use in Czechia in the period of more than 160 years, 1845-2010. Emphasis is also placed on the associated losses of agricultural and arable land, given that afforestation and increase of grassland took place essentially at the expense of that land. The main data source is the "Database of long-term land use changes in Czechia (1845-2010)", LUCC Czechia, based on cadastral records. It is a detailed monitoring which covers almost 9,000 so-called stable territorial units. Both the extensification processes and the overall intensity of land use (using the coefficient of ecological importance) are evaluated. Given that most of the Czechia's territory is still used as agricultural land, the thesis also includes an overview of the evolution of the selected agricultural intensity indicators. Attention is likewise paid to the wider context of land use changes at the European level. The essential part of the thesis is to build models of socio-geographical exposure of Czechia, which are comparable with the data on land use in the time horizons of 1845, 1896, 1948, 1990 and...
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The influence of socio-geographical exposure and other factors on the extensification processes of land use
Janoušek, Zbyněk ; Bičík, Ivan (advisor) ; Feranec, Ján (referee) ; Novotná, Marie (referee)
The main topic of the dissertation thesis is the evaluation of the influence of socio- geographical exposure and other factors (natural: altitude, inclination of slopes, productivity of land) on the extensification processes of the land use in Czechia in the period of more than 160 years, 1845-2010. Emphasis is also placed on the associated losses of agricultural and arable land, given that afforestation and increase of grassland took place essentially at the expense of that land. The main data source is the "Database of long-term land use changes in Czechia (1845-2010)", LUCC Czechia, based on cadastral records. It is a detailed monitoring which covers almost 9,000 so-called stable territorial units. Both the extensification processes and the overall intensity of land use (using the coefficient of ecological importance) are evaluated. Given that most of the Czechia's territory is still used as agricultural land, the thesis also includes an overview of the evolution of the selected agricultural intensity indicators. Attention is likewise paid to the wider context of land use changes at the European level. The essential part of the thesis is to build models of socio-geographical exposure of Czechia, which are comparable with the data on land use in the time horizons of 1845, 1896, 1948, 1990 and...
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