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The use of Playwork in communicating with the elderly
Blažková, Jana ; Haškovcová, Helena (advisor) ; Holmerová, Iva (referee)
The thesis is a study of the use of Playwork. The study first introduces the British playwork scheme, particularly with its traditional focus on children. Then it describes the current development of the technique in the Czech Republic. The author of the study tries to look at the possible use of Playwork on the elderly in care, particularly on those hospitalised long-term or those in residential care homes. The study gives examples of stimulation from urban and rural environments as well as the artificial stimulations given by care workers. It summarises the historical development and current form of the artificial stimulations. Another section gives examples of the data collected from interviews with play specialists and describes observations in several selected locations.
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Labor Law and Employment agencies
Blažková, Jana ; Soušková, Milena (advisor) ; Spirit, Michal (referee)
This diploma thesis is focused on a labor law and employment agencies. The aim of this thesis is to reveal the HR system of selected companies with regards to the employment agencies. Thesis is divided into two parts. Firts part provides a terminological basis and legal terminology for practical part. The practical part deals with analyzing activities of HR departments and systems of addressing potential employees. Practical part also contains working conditions of employers and their motivation systems. There are two types of materials. First of them are in-depth data obtained from interviews made with representatives of the HR departments and second of them are taken from my quantatitative research taken among potential employees. By comparing obtained information there is an evaluation of effectiveness of companies approach.
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Company Structure and Processes in a Travel Agency
Blažková, Jana ; Čermáková, Elvíra (advisor) ; Průša, Přemysl (referee)
The aim of this thesis is to map internal processes of the organisation, which shall be used as a basis for deciding about potential changes in the company structure. The first part describes the difference between small and medium size company and forms of organisational structure. The thesis also describes process management, approaches to process management and process mapping. The second part describes current state of the company. The processes of each department of the company are mapped and evaluated. A new organizational structure is suggested to contribute to more efficient organizational management.
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Hydrophilic polymers-based delivery systems for the transport and controlled release of siRNA
Blažková, Jana ; Laga, Richard (advisor) ; Vopálenský, Václav (referee)
Therapeutics based on siRNA represent a promising hope for the treatment of many congenital and acquired disorders. This method is based on posttranscriptional silencing of pathological gene or set of genes (RNAi process), which are responsible for the actual cause of the disease. Access is therefore based on the assumption of treatment options for the disease at the point of origin of the defect intervention at the molecular level, which is different from the conventional, so-called symptomatic therapy, which focuses only on the treatment or suppression of symptoms. Despite rapidly increasing understanding of gene function and cause a number of genetic diseases, the expansion of siRNA therapeutics limited the development of efficient and safe transport systems (vectors). In order to ensure efficient transport of siRNA in vivo conditions, the vectors must sufficiently reduce the size of the siRNA, protect it against degradation during transport, and release in the cytoplasm of the target cell. For this purpose they were developed sophisticated transport systems based on viral and non-viral origin. This diploma thesis is focused on the preparation of new transport systems, siRNA-based synthetic hydrophilic polymers, such as non-viral vectors. For in vitro testing the effectiveness during transport of siRNA...
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Polymer systems for siRNA delivery
Blažková, Jana ; Pechar, Michal (advisor) ; Šťovíček, Vratislav (referee)
The process of RNA interference (RNAi) is a natural phenomenon posttranscriptionally controlling gene expression by means of small double-stranded RNA molecules (dsRNA). Small interfering RNA (siRNA) is a small dsRNA that can be used for targeted gene silencing as an alternative therapeutic treatment of genetic diseases. For in vivo administration, siRNA must be protected against degradation to ensure its efficient delivery to target cells using sophisticated vectors. This work is focused on description of non-viral vectors based on cationic polymers, forming polyelectrolyte complexes with siRNA (polyplexes), and surface-modifying hydrophilic polymers enabling protection of the vector during its transport in the bloodstream.
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The central bank, its legal status and scope of activities
Blažková, Jana ; Kotáb, Petr (advisor) ; Kohajda, Michael (referee)
The Central Bank, its Legal Status and Scope of Activities Central banks are very powerful institution and central banking is a very complex discipline. Monetary policy, the most important activity of central banking, has become the key instrument of macroeconomic stabilisation. The aim of my paper has been to analyse all the areas of central banks' operations, aiming especially at monetary policy and its instruments, and also to tackle the recently emerged doubts about what the main objective of central banks should be. I also provide a review and an analysis of the current legal status of the Czech National Bank from the independence and accountability point of view. The first chapter of my work is dedicated to the history of central banking. Second chapter examines the individual functions that central banks carry out, with third chapter analysing the most important of them, the monetary policy. The last chapter is dedicated to the Czech National Bank (CNB) and is subdivided into four parts: the first one is outlining the history of CNB, the second one gives us the detailed overview of the individual functions of CNB, its main target and instruments CNB uses to reach the target. The third one is devoted to CNB relations with European Union and the fourth part focuses on the legal status of CNB...
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Pronunciation of two distinct "i" Vowels in the East Lach dialect
Blažková, Jana ; Veroňková, Jitka (referee) ; Palková, Zdena (advisor)
The vowel inventory of standard Czech includes five short vowels /a/, /e/, /i/, /o/, /u/ and five long vowels /a:/, /e:/, /i:/, /o:/, /u:/. Nevertheless, the dialectological literature indicates two distinct /i/ vowels, /i/ and /y/, in all the groups of the Lach dialects. The contrast of these two phonemes has a historical origin and has already disappeared in most of Czech and Moravian dialects. The objective of the diploma thesis "Pronunciation of Two Distinct /i/ vowels in the East Lach Dialect" is to witness the present state of the production and perception of two /i/ vowels in the East Lach dialect. Former dialectological texts still indicate the opposition as conserved, though considering the general recession of Czech dialects, the diploma thesis aims to verify if the East Lach dialect still distinguishes the /i/ and /y/ vowel and if this should prove to be the case, to determine the acoustic features that assure its perception. The research was based on minimal pairs and syllables, where the /i/ vowels were preceded by different consonants. The minimal pairs and syllables were inserted in text which was read by the speakers and recorded. Within the framework of the diploma thesis, 30 senior speakers of the East Lach dialect were recorded. Afterwards, six speakers were chosen to feature in two...
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The use of Playwork in communicating with the elderly
Blažková, Jana ; Haškovcová, Helena (advisor) ; Holmerová, Iva (referee)
The thesis is a study of the use of Playwork. The study first introduces the British playwork scheme, particularly with its traditional focus on children. Then it describes the current development of the technique in the Czech Republic. The author of the study tries to look at the possible use of Playwork on the elderly in care, particularly on those hospitalised long-term or those in residential care homes. The study gives examples of stimulation from urban and rural environments as well as the artificial stimulations given by care workers. It summarises the historical development and current form of the artificial stimulations. Another section gives examples of the data collected from interviews with play specialists and describes observations in several selected locations.
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