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In-vivo measurement of mechanical properties of biological materials
Čermáková, Viola ; Kuchařová, Monika (advisor) ; Klemera, Petr (referee)
Measurement of mechanical properties of many biological materials in vivo is based on the assumption that they can be considered as a visco-elastic body. This means that their mechanical properties under dynamic loading response partly to viscous and partly to elastic character. The visco-elastic biological materials include skin, blood walls, vessels, bones, tendons etc. Mechanical properties of biological materials depend on the structure of the material from the molecular to the macroscopic level. They also depend on age and health status of the organism. Obtaining of the standard values of mechanical parameters would be potentially useful as an indicators of functional age of organism also to study the influence of external factors (cosmetics, UV radiation) to changing the properties of biological materials and as well in terms of compatibility with artificial materials. To understand the ongoing processes in the skin, which was chosen as a biological material for measurement of mechanical properties in this thesis, the anatomical and physiological characteristic, including biochemical processes taking place in the synthesis of the main building components of the skin are needed to know. Aging of the skin is a complex biological phenomen consisting of two main parts of the so-called intrinsic...
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Rheology of the Knee Joint before and after the Surgical Treatment of the Rupture of the Anterior Cruciate Ligament
Strážnická, Lucie ; Jelen, Karel (advisor) ; Tlapáková, Eva (referee)
Název: Reologie kolenn~ho kloubu před a po chirurgickém řešení ruptury přednfuo zkříženého vazu Název v anglickém jazyce: Rheology of the Knee Joint before and after the Surgical Treatment of the Rupture of the Anterior Cruciate Ligament Cíl práce: Shrnout a analyzovat problematiku kolenního kloubu a získané poznatky využít při detekci změn reologických vlastností kolene po ruptuře předního zkříženého vazu před operací a v průběhu rekonvalescence. Srovnáill se zdravou končetinou a hodnocení změn průběhů hysterezních křivek v průběhu rekonvalescence. Navržení hodnot~cích parametrů pro popis stavu kolenního kloubu a jeho vývoje v průběhu rekonvalescence. Metoda: Bylo použito několik dostupných literárních zdrojů, ze kterých byly čerpány informace pro získání teoretického přehledu o problematice kolenního kloubu. Zároveň probíhala experimentální studie, která potvrdila či vyvrátila předem dané hypotézy. Výsledky: Výsledky poukazují na možnost detekce změn reologických vlastností kolenrubo kloubu po ruptuře předního zkříženého vazu. Bylo navrženo několik parametrů pro hodnocení vlastního experimentu, obecně lze ale říci, že bude ještě potřeba mnoha dalších studií, než bude zcela zřejmý výklad těchto parametrů a bude možné tyto parametry považovat za hodnotící standard. Dále je důležitá skutečnost...
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Possibilities of prevention of occupational damage to musculosceletal system of physiotherapists
LEŠÁKOVÁ, Jana
This work has dealt with possibilities to prevent the locomotive system?s damages suffered by professional physiotherapists. The goal of this work is to map the demands of the physiotherapist?s job and to propose preventive measures preventing locomotive system?s damages suffered by professional physiotherapists. Another goal of this work is to find out the actual state of the locomotive system of the chosen group of physiotherapists and to collect information relating to their ways of prevention and their care for their own musculoskeletal system. The work contains the theoretical and the practical parts. The physiotherapy has been defined in the theoretical part, two most frequent damages of the physiotherapists? locomotive system have been analysed, and possibilities of prevention have been described there. The practical part contains the quantitative pre-research and the qualitative research. The qualitative pre-research is based on findings and frank answers by physiotherapists from different health-care facilities (hospitals, health resorts, rest homes, rehabilitation centres), located mostly in the region South Bohemia. The quantitative pre-research was realised with questionnaires asking eleven questions. The qualitative research consists in inquiring of two physiotherapists. A conclusion has been drawn from the realised anamnesis, a kinesiologic analysis, and observations made during the physiotherapist?s work. Preventive measures have been suggested that could prevent the development of locomotive system?s damages. It is the secondary prevention in most cases. Further information was collected in Finland, in the town Rovaniemi during the student exchange. The stay in Finland enabled to compare preventive approaches relating to ergonomics and other risk factors during the physiotherapist?s work in Scandinavia and in the Czech Republic. It was concluded from the research that professional physiotherapists know the hazard relating to locomotive system?s damages. They also know prevention possibilities; however, not everybody of them has applied them adequately during his/her practice. This work can motivate all physiotherapists to think about results of practising physiotherapy for a long time and to improve measures preventing damages of their own locomotive system.
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Isosters of transkarbams, synthesis, properties and biological activity
Holas, Tomáš ; Hrabálek, Alexandr (advisor) ; Sedlák, Miloš (referee) ; Beneš, Luděk (referee)
1. SUMMARY The major aim of this dissertation was to synthesize and test isosteric analogs of T12. On the whole, 76 new compounds were prepared which have not previously been published. 28 compounds were tested as the transdermal permeation enhancers. Structure of these synthesized compounds was confirmed by FTIR, 1 H NMR and 13 C NMR analysis. Purity of the carbamate salts was verified by CHN analysis. With respect to the results, financial and time demandingness, permeation-enhancing activity was measured only on selected compounds. More than 400 permeation experiments were performed, more than 3000 HPLC chromatograms were analysed. To sum up, the permeation studies have shown that there is the relationship between structure and action of the studied compounds in the middle-lipophilic donor medium. Permeation-enhancing activity from the 60% propyleneglycol donor medium is in the following order: ester carbonate ketone ≥ amide = carbamate = alkane. Furthermore, there have been found another arguments confirming proposed mechanism of action of T12 - CO2 release in stratum corneum.
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Specific speech development of autistic children and development of communication capabilities of autistic children
Trávníková, Věra ; Hájková, Vanda (referee)
The objective of the final work is analysis of logopedie intervention in autistic children in the Vysočina region. The work offers an overall view of the care in the region, its possibilities, conditions as well as deficiencies. The whole work is divided into the theoretical and practical part and five chapters. In the first chapter I am dealing with defining the term of autism, terminology, etiology, occurrence and diagnostics. In the second chapter I am summarizing the knowledge related to the problem of communication with autistic children. The information was obtained by studying specialized literature and using practical experience. Problems are analyzed here as well as the basic forms of communication and its development. In the third chapter I am describing the system oflogopedic care of autistic children in the Vysočina region. The thesis further gives an outline of individual facilities that provide the care. I concentrated on special pedagogy centres and the data about clients with autistic spectrum disorders. In the fourth chapter I am presenting the research, its objectives, proposed hypothesis, used methodology, place of investigation and characteristics of the research sample. The investigation itself is described in the fifth chapter where I am analyzing the anamnestic data. In the following...
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Energy intensity process to save grass silage volume bags
ONDRÁČEK, Vojtěch
The aim of this work was to measure and evaluate the energy intensity of grass silage during storage in bulk bags. The values were measured on a line consisting of tractor and ma-chinery for storing forage. Further information was obtained from the service line. The results were over-straightened with technical and technological norms for agricultural production and other ways of storing silage.
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The Development and Transformation of the Czech Catholic Lithurgics in the Czech Catholic Literature between (1772) 1852-1962
Sklenář, Michal ; Novotný, Vojtěch (referee)
The thesis presents the portrait of forming, development and forms of Czech liturgics from the standpoint of works written by Czech authors in the Czech lands between 1607-1962. The time range covers the period since writing of the first Czech liturgy handbook through liturgics as an integral part of pastoral theology in the 18th and 19th century, its independence dating to the beginning of the 20th century and further development until the Second Vatican Council. On the basis of (1) bibliography of Czech liturgics, the project introduces (2) developmental tendencies of this discipline. In order to gain a comprehensive portrait of Czech liturgics, (3) educational institutions and the position of liturgics within the curriculum are studied. Liturgics is (4) approached with respect to the wider context of: (a) general ecclesiastic history, (b) Czech ecclesiastical history and (c) an overview of significant translations which gained acceptance in the Czech lands. Key words History of Theology, Czech Catholic Theology, Liturgics, History of Czech Catholic Liturgics
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The quality of furniture in the context of the brand Czech quality furniture
NOVÁK, Tomáš
The diploma thesis deals with the analysis of the qualitative level of furniture available on the Czech market in the context of quality labels. The most important mark of quality for the section of furniture is a brand of Czech quality, furniture, which is a central issue for this work. Introduction of thesis is dedicated to the theoretical analysis to ensure a closer acquaintance with the true issue. Continuing practical part of the thesis is devoted to the analysis of the quality of the furniture present on the Czech market, which was carried out by means of questionnaires. Addressed were primarily manufacturers of furniture, who do not possess the marks, and consumers. For obtaining the third were referred to research supplemented by the investigation carried out by the technical services of accredited for the testing of furniture. The outputs obtained from the questionnaires were linked in the form of a synthesis of the data which describes the current situation in the section of furniture on the Czech market. After analytic-synthetic part followed the discussion, which was created with the use of study Furniture 2010 published by INCOMA GfK. The last part of the work is result, which was primarily intended to confirm or refute the hypothesis set out, where applicable, to the summary of the most important knowledge related to the quality of the furniture on the Czech market.
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The Effect of Exercise Activity in Post-traumatic Conditions of Vertebral Column and Spinal Cord.
Nozarová, Eva ; Potměšil, Jaroslav (advisor) ; Bartůňková, Staša (referee)
Názcv: Vliv pohybové činnosti u poúrazových stavů páteře a míchy. The effect of the exercise activity up on the cases ofinjury of the vertebral column and the spinal cord. Cíl práce: Cíl práce je posoudit, do jaké míry lze na podkladě pohybových aktivit ovlivnit svalový a nervový aparát u pacientťt v ranné fázi po úraze. Zhodnotit výsledky. Metoda: Testování bylo provedeno na 6ti pacientech. Soubor tvoří 4 paraplegici a 2 tetraplegici. Vyšetřovaní jedinci podstoupili testování na začátku terapie, po týdnu a po měsíci. U pacientky číslo 1 byla hospitalizace delší než u ostatních pacientů, proto uvedu výsledky testování získané za období 3 měsícťt. K získání dat bylo využito testování pomocí funkčního svalového testu dle Jandy. Výsledky: U všech pacientů došlo ke zlepšení svalové síly. Pět pacientťt ze souboru mělo přidružené diagnózy, dva ze souboru komplikace, které zpomalily nebo komplikovaly pruběh terapie. Jen u jedné pacientky nedošlo ke zlepšení čití. Klíčová slova: Pohyb, páteř, mícha, transverzální léze, úraz, pacient.
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Strengthening of Wheelchair-bound People.
Domanská, Jitka ; Potměšil, Jaroslav (advisor) ; Dovalil, Josef (referee)
Název: Posilování vozíčkářů Strengthening ofwheelchair-bound people Cíl práce: Cílem této práce je zjistit, jaký význam má posilování pro vozíčkáře, zda přinese zlepšení v oblasti soběstačnosti a mobility, poskytnout souhrn informací o způsobu posilování a předložit návrh cvičební jednotky v posilovně pro paraplegiky. Také se budeme zabývat tím, zda má posilování vozíčkářů vliv na fyzické zlepšení jejich kondice a zda se cvičení projevuje také v psychické rovině. Metoda: Výzkum pozoruje skupinu 7 probandů při cvičení v posilovně v rehabilitačním centru, kam byli přijati po několika měsících po úraze většinou rovnou z nemocnice. K získání dat bylo využito pozorování, rozhovoru, studia osobní dokumentace, testování a na základě těchto údajů byly sestaveny kasuistiky. Dále pro doplnění informací byla využita anketa, kterou vyplnili sledovaní probandi a dále z důvodu většího počtu respondentů, byla předložena dalším pacientům tohoto centra, kteří měli velmi podobné podmínky pro cvičení v posilovně. Výsledky: Z vyhodnocení výsledků je patrné, že po dvouměsíčním cvičení sledovaných probandů v posilovně došlo ke zlepšení všech sledovaných parametrů. Dále z vyhodnocení ankety je zřejmé, že respondenti na sobě pocítili zlepšení v oblasti soběstačnosti, mobility a také zlepšení psychiky. Klíčová slova:...
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