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Surgical sex conversion
Dohnalová, Lenka ; Šamánková, Marie (advisor) ; Kříž, Jan (referee)
The aim of this thesis is to concentrate to inform the comunity with less known problems of nursing the patients with disorders of sexual identification - with transexuality. The persons with this disorder have genetic and somatic equipment belong to one sex, however their sexual identification is orientated to contrary gender. Surgical conversion of sex of transexuals forms oni y one of the aspects by complex approach to this complicated disorder. The decision when the surgery is indicated is up to sexologist and authorized by the committee. The commision decision is based on detailed and prolonged psychological approach to everyone. The observation is pointed at adaptation for new social status a:fter longtime hormonal treatment and follows a:fter operation and o:fficial conversion ofthe gender as well. Powered by TCPDF (www.tcpdf.org)
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Accounting for long-lived assets in internationally accepted accounting systems
Oplt, Lukáš ; Krupová, Lenka (advisor) ; Kudrnová, Lenka (referee)
This work deals with accounting treatment of tangible and intangible assets in International financial reporting standards (IFRS). It illustrates main problems and various methods when accounting for assets. Where deemed appropriate it indicates the accounting treatment of US GAAP. First chapter is concerned with general description of accounting harmonization and the Framework of IFRS. Second chapter deals with IAS 16 -- Property, plant and equipment. Third chapter identifies main differences between IAS 16 and IAS 38 -- Intangible assets focusing on issues related to the special nature of intangible assets. Fourth chapter works with annual reports and comes out with a statistic of IFRS methods and procedures adherence.
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Excessive public tenders with respect to construction work subject to open procedure
Csorba, Csaba ; Vopálka, Vladimír (advisor) ; Handrlica, Jakub (referee)
English summary Public procurement, as a relatively young branch of law, emerging from the American internal army regulations of public contracts, has become one of the most significant instrument of outsourcing execution of work, supply of products and services. In this work I am dealing with construction works, as they are the basis of present and future economic growth. Public tenders for infrastructure, flood control measures, reconstruction of schools and hospitals etc. effectively allocates financial means, but also creates new jobs and opportunities for economic operators hit by the global financial recession. The purpose of this master degree thesis is to analyze the current Czech public procurement legislation with respect of the regulations and directives of the European Union. As it is not possible to give a comprehensive preview of every single problem and question relating public procurement, the focus is on the most problematic part of the Public Procurement Code. The first chapter describes purpose of this specific branch of law providing a short historical background. It also concentrates on the principles of awarding contracts: acting transparently, treating the economic operators equally and avoiding their discrimination. The second chapter explains the basic differences between the...
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Using the Carousel Maze as a test of cognitive symptoms in an animal model of schizophrenia
Buchtová, Helena ; Landová, Eva (advisor) ; Jiruška, Přemysl (referee)
Spatial behaviour of animals is used to model cognitive human abilities such as declarative learning and memory. Cognitive deficits accompany a number of neuropsychiatric disorders and their treatment is most problematic. Schizophreniais one of these disorders. Behavioral, neurochamical, and molecular evidence point to a critical role of the NMDA glutamatergic receptors in the pathogenesis of schizophrenia. Disruption of their function results in behavioral and physiological changes including dysregulation of the depaminergic neurotransmission. This fact is used to model schizophrenia-related symptoms by systemic administration of NMDA receptor antagonists. Models combining administration of these drugs with behavioral tests aimed at specific cognitive deficits are of particular interest. This thesis use existing evidence to show that the Carousel Maze is such a behavioral test, which uses dynamic spatial learning to test the ability to coordinate discordant information and specific use of the relevant cues.
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Pregnancy, childbirth and child care during the first years of the life in the early-modern noble household in the light of ego-documents
Mejsnarová, Zdeňka ; Velková, Alice (referee) ; Šedivá Koldinská, Marie (advisor)
The bachelor thesis investigates the daily life of the Czech Early-Modern nobility during the period of pregnancy, childbirth, early childhood and especially iťs picture in ego-documents. On the basis of enunciation of the epistolary material, family memoirs and diaries describes essential aspects of the reception of this life cycle with reference to the specifics of the noble background and with emphasis on the differences or resemblances of present time. It observes both woman and man views of this problem and tries to implicate the significance of a child for the family, the importance of the christening, the choice of servants, the ways of health complication treatment and facing up to the death.
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Clients´ Perception of Spa Services in Aurora Spa
KROČÁK, Ladislav
An importance of spa services is especially in the medical treatment, but their economic significance is also very substantial. It significantly affects investment activities and an employment and it contributes to a regional development. Aurora Spa in Třeboň specializes in treating of musculoskeletal disorders, rheumatic diseases, post-traumatic and post-operative conditions and overall recondition of the body. Spa services in Třeboň have been, since a long time ago, associated with a natural healing source, which is abundant in this locality ? a boggy soil. Aurora Spa is not determined only for ill clients, but it is frequently visited by healthy people who undergo reconditioning and relaxation stays. The current trend heads toward to the fact that in the future the spa care covered from the public health insurance, will be in some way limited and clients will have to pay either a part or the entire treatment from their own financial funds. For this reason it is necessary to concentrate with spa service operators on a great clients´ satisfaction with their spa stay, so that they would return to the spa facility. Since I have worked for five years in the area of providing of the treatment services, I followed my bachelor thesis ?Clients´ satisfaction with spa services? by this diploma thesis, in order to re-map the clients´ satisfaction with services provided in above mentioned spa. I wanted to find out whether clients´ attitudes to the provided services had significantly changed from the research in 2009 year in my bachelor thesis. I used for the research the same questionnaire as in the research in 2009 year. 220 respondents were chosen for the research in the period of September 2011; 110 respondents had their stay covered by some of health insurance companies, either in a form of a complex or a contributory spa care and 110 respondents paid their treatment stay from their own funds as private payers. I supposed that men would be more satisfied than women and clients to whom some of the health insurance companies paid the stay, would be more satisfied than clients paying the stay from their own funds. After processing the data, there were not found out any significant differences in the satisfaction between these groups of respondents and in comparison with the research in the bachelor thesis from 2009 year there were not apparent any significant variations in the clients´ satisfaction with the services provided, which confirms, that the spa services in Aurora Spa are still on a very high level. Results of this diploma thesis can be used by employees of Aurora Spa to enhance the quality of provided spa service in all areas and to improve staff access to their clients.
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Incidence and prevalence of a disease in a district hospital over 3 years.
Matoušů, Barbora ; Střítecký, Rudolf (advisor) ; Lešetický, Ondřej (referee)
Branches of science such as epidemiology, clinical epidemiology, statistics and various statistical methods are by ground for activity of epidemiological-manager indicators. Incidence and prevalence are numbered among epidemiological-manager indicators. In condition of hospital Pelhřimov are these indicators written, analyzed and predicated for department of hospitalized in years 2005 -- 2007. At the same time is appraised use of capacities department of hospitalized, is made analyse and estimation of most often treated diagnosis and is watched progress their average time of treatment. The watching indicators are by one of series others records for manager decision-making by control of hospital.
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In vitro anti-proliferation activity alkaloids the Amaryllidaceae
Panenková, Kristýna ; Havlík, Jaroslav (advisor) ; Jarošová, Veronika (referee)
Summary
Natural phytochemicals are currently used in the treatment of many diseases. Cancers are just ones of them and they are ranked among the most common and the most serious. Phytochemicals in the form of cytostatics are used in chemotherapeutic treatment of cancer. In future there could be included among cytostatics also some alkaloids from the family
of Amaryllidaceae, whose testing for a selective cytostatic effect on tumor cell lines
of colorectal carcinoma Caco-2 and HT-29 and on normal cell lines of human intestinal epithelial FHs 74 Int is a subject of this thesis.
There were tested 17 alkaloids isolated from plants of Chlidanthusfragrans, Zephyranthes robusta and Nerine bowdenii. Particularly alkaloids from plant Zephyranthes robusta namely haemanthamine with this values: IC50 = 0.99 plus/minus 0.14 microM for tumor cells, Caco-2, 0.59 plus/minus 0.01 microM for tumor cells HT-29 and 19.47 plus/minus 8.86 microM for normal cells
FHs 74 Int, Lycorine with values IC50 = 0.99 plus/minus 0.08 microM for tumor cells Caco-2, 1.2 plus/minus 0.01 microM for tumor cells HT-29 and 22.68 plus/minus 0.09 microM for normal cells FHs 74 Int and Haemanthidin with values IC50 = 3.29 plus/minus 0.91 microM to tumor cells Caco-2, 1.72 plus/minus 0.11 microM to tumor cells HT-29, and 11.63 plus/minus 0.86 microM for normal cells FHs 74 Int proved a significant
anti-proliferative activity.
From these results there is evident the selectivity against colorectal cancer cell lines. For this reason, those tested alkaloids are suitable for further testing and for study of their biological activity against tumor cells in the terms of in vitro and in vivo.
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Způsobila alkoholová prohibice pokles počtu dopravních nehod spáchaných řidiči pod vlivem alkoholu?
Brabenec, Tomáš ; Montag, Josef (advisor) ; Potužák, Pavel (referee)
This paper tries to find out whether a short ban on sales of liquors reduced the harmful use of alcohol with respect to motor vehicle accidents. I make use of short (two weeks) alcohol prohibition which was imposed by the Ministry of Health Care in the Czech Republic in September 2012 aiming to stop the deadly wave of methanol poisoning. To estimate the effect of prohibition on the number of road traffic accidents, I exploit the methodology of differences-in-differences. I use daily data about traffic accidents from the Czech Republic (treatment group) and from neighboring countries such as Austria, Germany and Poland (control group). The result suggests that there is no significant drop in term of road traffic accidents.
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Quality of life in patients with coronary artery disease after percutaneous coronary intervention treatment
Melkovičová, Stanislava ; Štefančíková, Mariana (advisor) ; Votroubková, Michaela (referee) ; Hodač, Martin (referee)
Key words: quality of life, assessment of quality of life, coronary artery disease, percutaneous coronary intervention Bachelor's thesis is focused on assessment of quality of life in 50 patients with chronic coronary artery disease after receiving percutaneous coronary intervention treatment. Risk factors, signs, diagnostic techniques, treatment and prevention were mentioned. Practical part of the thesis is based on questionnaire survey. The objectives are to evaluate the quality of life in patients with chronic coronary artery disease before treatment and assess the effect of treatment on further quality of life in these patients. Patients' compliance of preventive interventions and important differencies between both sexes were measured as well.
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