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Pharmacological influence of endothelial dysfunction in experimental model of diabetic rat
Přidalová, Hana ; Nachtigal, Petr (advisor) ; Štaud, František (referee)
The aim of this thesis was to evaluate the expression of cell adhesion molecules in femoral artery after induction of diabetes and after the administration of sulodexide. We focused on the expression of PECAM-1, ICAM-1 and VCAM-1 vessel endothelium. The analysis was provided by means of immnohistochemical staining. Male Wistar rats were divided into three groups. Control group received saline, the second group received sulodexide (SLX, 100 UI/kg/den). Diabetes was induced by the streptozotocine injections (30mg/kg/den i.p.) during consecutive free days. The treatment was administered for 10 weeks. Biochemical results confirmed the induction of diabetes; however the suledoxide treatment did not decrease glucose levels when compared with non-treated diabetic animals. The ICAM-1 expression was slightly increased in diabetic treated rats when compared with control rats however suledoxide treatment did not affect ICAM-1 expression. VCAM-1 expression was not detected in any rat from control, diabetes and/or suledoxide treated rats. In conclusion the results of this pilot study showed that diabetes induced by the administration of streptozotocine did not resulted in significant induction of endothelial dysfunction. Thus the possible effect of suledoxide treatment could not be evaluated in this study.
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The Reasons for prostitution in South Bohemia Region
DOSCHKO, Václav
The Bachelor{\crq}s thesis deals with prostitution issues in the South Bohemian region and its development through the secondary and content analysis of data gained from the Czech Republic police, from the Management of South Bohemia. The prostitution accompanies the humankind the all time of its being. It is possible to define it in this way: Everybody who has sex or carries out an activity for purpose of sexual satisfaction for a consideration or in order to gain certain advantage or interest, without emotional attitude and without regard to the choice of a partner, commits the prostitution. Before the year 1990 there was the prostitution in a latent form in the Czech Republic, as a part of shadow economy. The repression was the only form of its regulation, which went out from the Penal Law No. 140/1961 Coll. Article 203 on Sponging; on its basis the prostitutes who had no employment were inflicted. In 1990 the Offense Act No. 150/1991 Coll. was repealed due to the amendment of the Act No. 140/1961 Coll., the Act No. 175/1990 Coll., and the Article 203 of the Penal Law on Sponging. These legal acts are in addition to the opened borders, foreign tourism boom and stratification of Czech citizens in connection with the enormous extension of publicly and hidden practiced prostitution in the Czech Republic. The aim of the thesis is to inform the reader about general facts concerning the prostitution. Further it should point out the social-pathological aspect of the problem. During my writing I got from the available literature, other sources were dossiers from the Czech Republic police, the Management of South Bohemia and the invaluable experience of its executives. According to the gained and processed information the numbers of prostitutes are being reduced {--} the prostitution in the South Bohemian region is decreasing. The hypothesis was confirmed.
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The electrostimulation the spermiation in the crayfish
KUBEC, Jan
The crayfish are important and indispensable animals in aquaculture. In the aquatic environment, they have a role as predators, food for other fish, detrivors and they are an important element in the circulation of the energy and the nutrient in the aquatic ecosystem. Today, number of the european crayfish species populations is decreasing. It is caused by unfavourable regulation of streams, water pollution and the occurence of crayfish plague. The main purpose of present study was examining the impact of electrostimulation on the males of the crayfish and obtaining sex products (the sperm). The principle of this research was determining whether the male of crayfish are able to extrude spermatophore with sperm by an electric stimulus. The transformer was used as resource alternating current in experiments. All experiments conducted in a laboratory of experimental device for fish farming in Vodňany. Experiments were conducted in 2011 on a male of the spiny-cheek crayfish (Orconectes limosus), the signal crayfish (Pacifastacus leniusculus) and the red swamp crayfish (Procambarus clarkii). The results of this work and success of the experiments suggest, that electrostimulation could be used for obtaining sex products (the sperm) from crayfish males. Results from a laboratory of electron microscopy confirm the harmlessness of electrostimulation on the shape and structure of sperm. The sperm can be used to artifical insemination of the crayfish eggs in future. However, sperm capacitation is problematic.
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What Socioeconomic Factors Explain Type 2 Diabetes Prevalence?
Makarevich, Veranika ; Votápková, Jana (advisor) ; Bryndová, Lucie (referee)
The study aims to identify the influence of socioeconomic factors on the prevalence of type 2 diabetes for individuals aged 27 and older in the Republic of Belarus. We analyze data from the Diabetes Survey conducted by the Endocrinology Medical Center in Minsk and the Ministry of Health of the Republic of Belarus from 2011 to 2015. The association between socioeconomic factors and the prevalence of type 2 diabetes is examined using logistic regression with sequential adjustments for clinical and behavioral predictors. Our findings indicate that individuals with lower income and educational levels are more likely to suffer from type 2 diabetes than those in higher income and education groups. Moreover, the prevalence of type 2 diabetes decreases as income and educational level go up. Furthermore, this association remains significant even after further adjusting for various behavioral and clinical factors. In addition, we confirm that type 2 diabetes is more prevalent among overweight / obese, physically inactive and older individuals. These findings suggest that strategies for preventive diabetes programs should be focused on socioeconomic environment rather than on individual risky behavior only.
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Risks of the Road Transport And Their Factors
HEJKRLÍK, Lukáš
The bachelor thesis Risks of the Road Transport And Their Factors deals mainly with the risk of avenues that are planted along the Czech roads. I have focused on basic definitions that are closely connected to road transport and I have also focused on ex-planation of practical methods used when assessing traffic accidents in the theoretical part of the thesis. In the practical part of the thesis I have focused on concrete analyses related to existence of avenues along the Czech roads. These analyses confirm the de-gree of risk of road transport itself but especially fatal consequences of accidents caused by a crash with a fixed obstacle that is often presented by a tree from avenues along the roads. The analyses discovered that the accident rate in the Czech Republic is decreasing. However, the fact that the risks connected with consequences of tree crash are decreas-ing more slowly, is still alarming. The detailed graphs and tables in the bachelor thesis show the number of casualties connected to a traffic accident caused by a crash with a fixed obstacle and they prove that the consequences of accidents caused by a crash with a tree are worse than the consequences of accidents caused by a crash with a crash bar-rier, even though they both are considered a fixed obstacle. Last but not least the costs and total economic losses caused by the highest negative factor, i.e. the accident rate, are calculated by using the tables and graphs.
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The impact of crisis on the market of building society
NOVOTNÝ, Libor
The theme of this thesis is the impact of crisis on the market of building society in the Czech Republic. The main aim of thesis is to analyze the impact of crisis on the market of building society. The theoretical part describes the concept of financial crisis, the kinds of financial crises and overview of the history of financial crises. It also describes the contemporaneous crisis and its causes. This section also provides information about the basic concepts, process and legislative conditions of building society. At the end of this part are described history of building society and the development of building society market in the Czech Republic. In the practical part is analyzed the impact of crisis on the market of building society in the Czech Republic. It includes an analysis of the economic environment in the Czech Republic and the analysis of business and financial indicators. In conclusion of the practical part is the summary and evaluation of the impact of crisis on the market of building society. The result of this part confirms that the main impact of crisis on the market of building society in Czech Republic is a decrease of client demand.
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Quality of life of senior women that suffer from incontinence
Kršňáková, Veronika ; Zámečník, Libor (advisor) ; Langrová, Eva (referee) ; Václavíková, Zdena (referee)
This bachelor dissatation deals with the problem of female incontinence. Theoretic part is devoted anatomy lower urinary tract, physiology discharging and detail described individual kinds of urinary incontinence, cause, treatment and prevention. In empiric part I felt to valorize how the urinary incontinence affects quality of life. I also tried to find out how long was the time interval before the patient finds the medical hep and if there is enough awareness about the illness and its treatment. My research confirmed the fact that it is important to improve education and have enough Information available about this problem in order to identify the early symptoms and eliminate negative motions. The most important is to improve understanding of women's feelings and needs and to (decrease) eliminate the embarrasment rated to this problem.
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The usage of algae in biogas transformation
Paroulkova, P. ; Sukačová, Kateřina ; Murgasová, K. ; Vítěz, T. ; Chovanec, J.
Using of algae in a biogas transformation is still in the beginning. However, the microalgae have large potential from the perspective of growing demands on biogas quality and trend of using,natural resources. First of all, it is their ability to fix carbon dioxide (CO2) using photosynthesis and presumed ability of some algae to metabolize hydrogen sulphide (H2S). Biogas contains not only required methane but also components causing its worse quality such as mentioned CO2 and H2S. Therefore, the algae are potential biological systems for biogas-conditioning. The microalga Chlorella pyrenoidosa Chick (IPPAS C2) was used for fixation of CO2 and H2S in our experiment. The microalgae were cultivated in a medium BG 11. The algal suspension was aerated with the biogas during two weeks. Different values of CO2 concentration measured in the input and output confirmed decrease of CO2 caused by intensive growth of algal culture. Decline of H2S was not confirmed.
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Design and verification of the intervention program for client with metabolic syndrome visiting Wellbeing Centre VŠTJ MEDICÍNA in České Budějovice
BENÝŠKOVÁ, Ivetta
Presented personal case study shows the effects of targeted intervention motion drawn up the plan and verifying its functionality for clients with severe metabolic syndrome. The client is a 39-year old obese (BMI of 32.3, height 164 cm, weight 87 kg) diabetic. Emphasis was placed on the program-controlled weight reduction exercise. The client for 13 weeks completed 53 hours of physical activity of aerobic and weight training character in 46 training units. The results confirm the success of case reports targeted exercise intervention in the therapy of obesity and metabolic syndrome. Significantly decreased the value of glycated hemoglobin, waist circumference shrank by 5 cm, total weight reduction amounted to 2 kg. Within three months, an improvement in client anthropometric, biochemical and cardiovascular indicators.
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Monitoring of changes in distribution of amphibians in Novohradské Mountains and their piedmont
ŽALUD, Štěpán
The changes in the occurrence of amphibian were monitored in the region of Novohradske mountains and in its foothills in seasons 2009-2010. Observation was focused on the presence of 11 species of amphibian in 31 selected locations. The results confirmed a significant decrease in the frequency of the species: Smooth Newt (Lissotriton vulgaris), Alpine Newt (Mesotriton alpestris), Warty Newt (Triturus cristatus) and synklepton Pelophylax synklepton esculentus. A mild decrease by European Tree Frog (Hyla arborea) and Common Spadefood (Pelobates fuscus). The balanced condition was found out by Fired Bellied Toad (Bombina bombina) and Yellow Bellied Toad (Bombina variegata), Common Toad (Bufo bufo), Grass Frog (Rana temporaria), Moor Frog (Rana arvalis) and Agile Frog (Rana dalmatina). Species were determined according to morphological characters. Observed data were compared with results of surveys of monitored sites from years 1999-2004.
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