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Psychological aspects of coping with a serious somatic disease: women diagnosed with cervical cancer
Hejnová, Kateřina ; Loneková, Katarína (advisor) ; Hrachovinová, Tamara (referee)
The diploma thesis "Psychological aspects of coping with a serious somatic disease: women diagnosed with cervical cancer" deals with psychological demands of the adaptation to the oncological disease with focus on specifics of the cervical cancer diagnosis. The theoretical part first introduces specifics of cervical cancer with consideration of patients' experience and then provides the issue of coping with the oncological disease in terms of coping and defense mechanisms. Then it elaborates the psychological adaptation to cancer disease with focus on other aspects linked to society, patients and disease altogether with problems in coping with oncological diagnosis. The theoretical part of the study is concluded with the description of demands and patients' experience in each clinical stage of the disease. The empirical part describes supporting psychological and other aspects, which help women to cope with cervical cancer. It also pays attention to the change of these aspects and needs with regard to clinical stage of the disease (treatment, remission and relapse) and specific demographic data (age, children, size of residence, partnership). It is also focused on those of supporting aspects, which are appreciated or missed by the patients within the treating team (doctors and other medical staff)....
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Vaccination against the papilomavirus infections at female students 8th and 9 elementary school classes in the region Písek and their awareness of the issues
MAREŠOVÁ, Lucie
This dissertation thesis touches very current and among public and experts often discussed topic. It concerns particularly matter of papillomaviral infections and vaccination against them. The research proved vaccination-coverage level of respondents and also their knowledge level. The vaccination-coverage level of girls is very high (almost 80%). A lot of girls also used possibility of full vaccination in the age of 13. This dissertation thesis should serve as a source and summary information about HPV viruses, diseases caused by them, about ways of transmission and epidemiological measures. Furthermore it also informs about cervical cancer, risk factors, diagnostical possibilities, therapy and at last but not lest about prevention of cervical carcinoma.
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EFFECTIVITY OF SCREENING PROGRAMS OF NEOPLASMS IN CZECH REPUBLIC
Valášková, Veronika ; Pechholdová, Markéta (advisor) ; Nývlt, Ondřej (referee)
This diploma thesis deals with the national screening programs for cancer diagnosis. The goal of this thesis is to find a proper way how to evaluate the effectivity of screening programs as well as their influence on the intensity of mortality from certain types of cancer. For the purpose of finding out necessary information were used data related to the diagnosis of colorectal cancer, a diagnosis of cervical cancer and breast cancer in the population of the Czech Republic between 1977 - 2011. This thesis is divided into eight chapters. The first chapter is an introduction to the topic and contains the description of the main goals. The second chapter defines terms that are crucial for this thesis. The third chapter is devoted to data sources and institutions that collect different types of data and health statistics. The next chapter deals with the epidemiology of all described types of cancer and also provide information on risk factors and symptoms of the disease. The fifth chapter looks back at trends in mortality and incidence of the most common malignant tumors in the Czech Republic. The sixth chapter describes planning and implementation of screening processes. The seventh history of screening programs in the Czech Republic. The eighth chapter deals with the rules and regulations of the EU Council and the World Health Organization. The ninth chapter represents the final assessment of Czech screening programs, compared both to the WHO guidelines and the results in the world. The last chapter is including description of mortality and their reaction on screening programs. Text describes even comparison with two other European countries (Germany, France).
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Examination of HPV as part of cervical cancer prevention
PETŘÍKOVÁ, Petra
Sexually transmitted HPV infection (human papillomavirus), or infection with human papillomavirus, is a decisive factor in cervix carcinoma etiology. Human papillomaviruses are considered to be the most frequent sexually transmitted infection worldwide. In women, the life-long risk of infection is 80%. High-risk genotypes (high-risk HR HPV 16, HPV 18) were classified among carcinogens. The risk of cervix carcinoma in a woman who is HR HPV positive is 100 to 400 times higher compared to a woman who is HR HPV negative. The first part of my thesis contains a brief theoretical overview of HPV history, structure and classification. The next part deals with the ways of HPV transmission and the incubation period of the pathogenic agent in question. The incubation period as well as the replication cycle of the virus depend on the extent of infection and on the status of the immune system. Increased occurrence of papillomavirus infection is found in persons with a damaged component of cell immunity. In the further part of the thesis I focused on the diagnostic procedures and tests proving HPV infection including its clinical manifestations. Continued HPV infection, together with other relevant factors (smoking, immunodeficiency, lack of vitamins, stress, vaginal infection and hormone influence), increases the probability of cervix carcinoma occurrence. Here I also mention the histopathological classification, prognosis and treatment of these tumors. Considering the occurrence of cervix carcinoma, the situation in the CR is not as favorable as in other advanced countries where the screening is more effective. For comparison, the incidence and mortality in the CR are presented within global scale. Further on I attempted to stress the importance of primary prevention, mainly vaccination. The parts of secondary prevention mentioned in the thesis are preventive examinations, colposcopy, oncological cytology, serological methods and HPV test. The aim of my thesis is to emphasize the importance of testing for human papilloma virus HPV tests carried out in high risk group of women aged over 35 years within the system of preventive examinations. However, nowadays these examinations are accomplished just in women with an abnormal cytological finding. My thesis summarizes the quantitative findings as regards HPV tests done on the basis of determining the nucleic acid of human papillomaviruses by hybridization method with enhanced signal using chemiluminiscence detection. The detection of HPV was achieved with the use of the sets hc2 High-Risk HPV DNA Test and hc 2 HPV DNA Test from QIAGEN company. The thesis includes results of the tests for high-risk types of human papillomaviruses (HPV 16/18/31/33/35/39/45/51/52/56/58/59/68) found in 767 women over the period from January 1 2010 to December 31 2013. The tests were carried out at the Medical Microbiology Ward of the Hospital Jindřichův Hradec, a joint-stock company. The group of women with already positive cytological finding was divided into six age categories to highlight the high-risk groups of women over 35 and over 65. As I myself belong to the high-risk group over 35, my intention was to prove the hypothesis that the cause of the cytological changes in women over 35 can be attributed to the dangerous types of human papillomavirus. Finally, after carrying out the analysis of the obtained results, I attempted to propose a solution which could be used in practice.
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Knowledge, attitudes and practice of vaccination against HPV - the male and female population
MANOVÁ, Michaela
The theoretical part summarizes information about cervical cancer, which is caused by the human papilloma virus. Cervical cancer is ranked on the second place in the incidence of cancers world wide. Virus HPV affects both men and women. For men, it results in the emergence of genital warts or cancer of the penis. Although there are existing opportunites for effective prevention for men, the focus is more on the female population.This thesis looks at the current problems in the prevention of cervical cancer, which affects an ever growing number of women and men. In this work, we find out how informed are the young people about cervical cancer, their knowledge about possibilities of prevention, and experience of vaccinated respondents in the age in which this vaccination is recommended, that is, before the start of an active sexual life. In the research part, is a summary of a questionnaire, which was done among pupils of a primary school in Plzen. The age range of respondents was 13- 16 years. The research included both girls and boys. The assumption that girls are more informed and are more interested in information regarding cervical cancer and boys on the contrary don?t search for this information because they think that this problem does not concern them , was largely confirmed by this research.
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Evaluation of the vaccination against the papilomaviruses at the students of the University of South Bohemia in České Budějovice
SHÝBALOVÁ, Ivana
The diploma work concerns the actual problem of papilomavirus infection and the vaccination against its originators. The gravity lies in the human-organism attack and the further proceeding changes in the human cells and mucous membranes. In many cases this leads to the pre-cancer states or even worse, to the cervix carcinoma. The work is divided into two parts, first theory, and second practice. The aim was to evaluate the vaccination against papilomviruses at the female-students of the University firstly, secondly to map the topic knowledge, and thirdly to monitor if the female-students visit their gynaecologist on regular basis. The theory concerns all the epidemiology, virology, clinical and diagnosis aspects of the papilomavirus infections, including the vaccination as a prevention possibility. In practice, there were run two anonymous questionnaire searches, first aimed on the female-students, second on the male-students only. The questions were focused on the level of the topic knowledge and the level of the both sex students vaccination, including the reasons of their non-interest in the possible vaccination, next the frequency of the girls? screenings in the gynaecologist practices. The research proved certain level of the respondents? topic knowledge and compared the existing differences among faculties. Another research conclusion is that the vaccination of the female-respondents is not very high, only 23,75% has already been vaccinated against the virus. Many young ladies underestimate the vaccination, and have more or less serious reasons why not to have them vaccinated. More than half of the respondents don?t do so because of the vaccine high price. This work should serve the women and young ladies, but also the young men as a source of the needed information. This means to improve the virus knowledge itself, its means of transmission, the diagnosis process or the treatment possibilities; overall the ways of primary prevention, with the ways of infection expanding prevention.
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Womenś Informed Awareness of Cervical Cancer Prevention
GAŠPÁRKOVÁ, Věra
The purpose of my thesis was to determine the level of women's awareness of cervical cancer prevention, because cervical cancer is a serious disease affecting women of all age categories. As the occurrence of the disease is relatively high nowadays and there is no organized screening for cervical cancer in our country, it is useful to survey the awareness of women of preventive examinations available, as well as the possibility of vaccination against the HPV infection. The survey was conducted by the quantitative research method. Data were collected by the anonymous questionnaire technique. The questionnaires were addressed to women of all age categories in different places of the South Bohemian region. A total of 160 questionnaires had been handed out, 95 % of which came back filled in. Some of them could not be taken into account due to inaccurate data, so the final number of relevant responses was 148 (100%). The data were gathered in October, November and December 2008. In the thesis I stated six objectives and six hypotheses referring to women's awareness of cervical cancer prevention, vaccination and their attendance in preventive examinations. All the goals were met and the research was to confirm or reject the hypotheses stated. The first hypothesis presumed that young teenage girls under 18 are not informed of preventive gynaecological examinations. The evaluation of questionnaires of that age group did not confirm the hypothesis. All the other hypotheses were confirmed, and so good awareness of women was identified. It is advisable to provide education on cervical cancer prevention in practice. Midwives can inform women in hospitals, consulting rooms and other health care facilities. To spread useful information, special brochures and leaflets as well as other sources such as the Internet can be used and special lectures can be organized. The results of my research can be published in specialist magazines. The purpose of cervical cancer prevention is an early detection, treatment and consequently mortality rate reduction in women with this diagnosis. But every woman is fully responsible for her own health and she is the one to care most.
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The evaluation of attitudes towards prevention of papillomaviruses infections in girls and women in České Budějovice and value of vaccination against papillomaviruses infections in students of ZSF JU.
FÜRSTOVÁ, Romana
Human papillomaviruses, also known in English as human papillomavirus, shortened HPV, are uncoated DNA viruses, called naked, that belong to the family Papoviridae. These are viruses which are known as small tumour viruses. Today, more than 100 types of human papillomaviruses are known, of which more than 40 infect the genital tract of men and women. Human papillomavirus is not only an agent of genital warts, which have been known and described in the medicine for two millennia, but also plays an important role in the development of cancer. Since the first thoughts about the relationship of viral infections and tumour, the development of knowledge came to the current view of HPV as an independent risk factor, particularly in the pathogenesis of cervical cancer. Papillomavirus types 16 and 18 play an important role in the pathogenesis of cervical cancer. Today, it has been scientifically proven that papillomavirus infection is a starting factor for cervical cancer. Cervical cancer is not only a serious health problem but also a medical and social one in Europe. It is the second most common cancer in women worldwide. HPV infection is currently the most common sexually transmitted disease. Up to 80 % of sexually active population meet HPV infection during their life, the highest prevalence rate of HPV is found in the age group of 18-25 years. Cervical cancer is a preventable disease after the development of a vaccine against HPV and introduced screening. The first, theoretical, part of the paper gives a comprehensive overview of various aspects of human papillomavirus infections based on the study of professional literature. In the second, research, part of my paper I focused on evaluating the approaches to the prevention of human papillomavirus infection as well as the cervical cancer in girls and women in České Budějovice and also the level of vaccination in students of the Faculty of Health and Social Studies against HPV. Based on the objectives of the paper hypotheses were drawn. Both objectives of the paper have been achieved.
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University students awareness about cervical cancer risk and its prevention
MÜLLEROVÁ, Jana
In worldwide basis, the carcinoma of cervix is the second most frequent malignant tumour in women. There is up to 1200 new cases diagnosed in our country every year. Considering the sad fact that more than 400 women die in our country every year, the battle against the carcinoma of cervix became recently one of the priorities of the Ministry of Health of the Czech Republic. The nationwide screening focused on early detection of cervical cancer was launched in our country in 2008. The dissertation paper entitled ``Awareness of university students of the risk of cervical cancer and its prevention`` is mainly focused on monitoring of awareness of university students of the risk of cervical cancer disease and the possible ways of its prevention. The assessed group was made of university students, young women from South Bohemian and Prague universities. In the research part of the dissertation the author used a method of questioning with the technique of data collection using anonymous questionnaire. The research has revealed that the students have basic knowledge on the issue of cervical carcinoma, namely in the area of risk and prevention. It was also found that the awareness of the students of the South Region on this issue was much better than of the students in the Prague region. Despite the overall positive results, the research shows the need to inform the public especially about the hazards of smoking as a possible risk factor associated with cancer. It is also necessary to expand knowledge of women in already developed symptoms of the disease. There is currently only one known - bleeding after intercourse. In the area of prevention it is also desirable to highlight the availability of some special examinations for men, while appealing to the possibility of lifelong disability as a serious consequence of this disease. Research shows that it is still necessary to inform more and better the public about this issue. From the views of the respondents it is clear that in addition to ads aimed at promoting vaccination, the problems of the disease is poorly presented. This is confirmed by the fact that students do not know any organization focused on this problem. To a good awareness of women in this field, in terms of risks, prevention and possible vaccination, should contribute especially gynaecologists, together with the midwives, because as part of the preventive visits they have the opportunity to address the women and to specifically discuss the issues with them. It is unfortunately evident from the research that these doctors inform minimally about the possible ways of prevention. In my opinion, to respond to the observed facts and to refine and improve the information system for a maximum possible way it is in the interests of all women and girls, whether by improving the own work of gynaecologists, as well as improving awareness about this problem through the media or by using a variety of booklets and leaflets in offices of other physicians, that are currently seen only sporadically.
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