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The role of Aspirin in the prevention of Colorectal Cancer
Galas, Ron Eric ; Kment, Milan (advisor)
Non-steroidal Antiinflammatory Drugs have been shown to play an important role in the chemotherapeutic prevention of Colorectal Cancer. Their mechanism in doing so has been proven as far as scientific works today allow results and an understanding of this mechanism. Without a doubt, many aspects of this drug in terms of chemotherapy tailored to the treatment of Colorectal Cancer remain to be illuminated and are subject to further investigations. Whether a cyclooxygenase inhibitor can be used as a chemopreventive agent needs to be assessed in each case individually and the whole view of a patient must be taken into account considering his overall status of health and the exclusion of the potential harm of side effects. Given the fact that these drugs provide protection of Colorectal Cancer to a certain extent, their use will most probably increase in countries where they are easily accessable.
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Comparison of business conditions of Czech republic and Singapore
Severová, Lucie ; Zeman, Karel (advisor) ; Vostrovská, Zdenka (referee)
Question of barriers to business is in the Czech Republic criticised for a long time, but until now have been taken only partial actions and complex change is still missing. For a comparison of business conditions I chose Singapore, because it has very favourable business conditions in recent years, while the Czech Republic markedly fall behind on a worldwide scale. Methodological part of the thesis contains an analysis of conceptions that serve as a base for the comparation of business conditions. The conceptions are concerned with starting a business, getting credit, trading across borders, self-dealing, theory of procedural formalism, tax theory, labour relation, getting and transferring real estate. Consecutive analytical part of the thesis compares business conditions in the Czech Republic and in Singapore according to criteria accepted by The World Bank. The criteria are focused on administrative, financial and time cost of starting business, registering and transferring real estate, proceedings at law, international trade. Further criteria are determinants of labour relation, law protecting of investors against self-dealing, informative barriers to getting credit, determinants of paying taxes. The objective of this bachelor thesis is to analyse differences in business conditions between the Czech Rupublic and Singapore and propose arrangement for improvement law and economics conditions for business in the Czech Republic.
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The invisible hand of market: Adam Smith and G. W. F. Hegel
Krištofóry, Tomáš ; Pavlík, Ján (advisor) ; Lipka, David (referee)
Hayek's interpretation of Smith's invisible hand as a metaphor for the theory of spontaneous order still holds as the only authentic interpretation of that famous phrase, despite all criticism. Although not many authors noticed it, Hegel was a theorist of spontaneous order, namely also a theorist of the spontaneous order of market economy. There is evidence that Hegel followed here Adam Smith's teachings about the invisible hand. The invisible hand is present in Hegel's writings as an element, from what sprang his theory of spirit. That means that his theory of spirit is a general theory of spontaneous order, although written in metaphysical manner. However, being a theorist of spontaneous order didn't prevent him from being an interventionist. He was led to interventionism by his synoptic fallacy of mind. He never tried to apply this fallacy on the studies of the market economy. Marxists did that. Some of recent scholars (Sciabarra, Johnson, and Cristi) identified Hegel's theory of spontaneous order, but their interpretation wasn't perfectly in accordance with Hegel's texts. How these authors denied Popper's and Hayek's incorrect opinion that Hegel was a totalitarian, thus it is needed to enrich studies of mentioned current scholars. Here it is taken into account only what Hegel wrote, not later authors about him. This thesis is also an attempt to evaluate the history of economic thought from the standpoint of Smith's and Hegel's methodology.
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Prevention of Cervical Cancer
Kafková, Simona ; Šafář, Petr (advisor)
Cervical cancer is a disease characterized by an abnormal growth of cells in the uterine cervix. It is caused by an infection with a range of high risk oncogenic human papillomavirus (HPV) and it is now accepted that more that 99 % of the cervical cancer is initiated by the HPV infection. HPV is the most common sexually transmitted viral disease. Most of the HPV infections are only temporary and human organism can destroy the infection with its own immune response. A persistent infection can lead to the malign transformation and an uncontrolled cell proliferation. There are more than 10 years between an epithelial infection and cervical cancer. Prevention of cervical cancer includes an HPV protection, an early diagnosis and a treatment. In spite of the fact that there has been enormous progress in the area of the cervical cancer prevention when vaccination against the most common HPV types was discovered, an early precancerous diagnosis through the use of the full-area screening still remains an essential precaution. The screening still needs to be provided not only to unvaccinated women but also to the immunized ones because current vaccines protect only against 80% of the oncogenic HPV types. Because of the prolonged absence of clinical symptoms in precancerous stages, the cytodiagnosis is the only method...
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EATING DISORDERS - MONITORING OF TEENAGE GIRLS AWARNESS IN THESE PROBLEMS
TICHÁ, Jana
In this bachelor´s thesis I am describing eating disorders. I have chosen this topic for its urgency and still increasing popularity of slenderness and excessive thinnes amoung young people. According to MKN{--}10 identiccaly with DSM-IV American psychiatric association include in the concept of eating disorders two clearest defined syndroms: anorexia nervosa and bulimia nervosa. Both of these defects are very similar, the following signs are charakteristic: intensive effort at slimming connected with restriction of taken energy and with oncreasing outlay of energy, being afraid of fatness, an extrem attention to food, own body and weight. Eating disorders mostly appear in adolescent girls and young women. Women are suffering from this defekt ten-times more than men. They ussualy have a chronic course, serious mental, somatic and social consequences. There is not a key risk factor and there seem to always occur a complex constellation of social, cultural and family influence factors, life events and personality features with developmental and biological factors. Food intake disorders prevention is still at a very low level in the Czech republic. However high attention is paid to prevention and dealing with overweight.
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Prevention of postopertative complications in gynaecological surgeries
Vinařová, Šárka ; Šafář, Petr (advisor)
Prevention of postoperative complications is a list of precautions, which must be taken before, during and after the surgery. It includes local complications, for example postoperative sickness, which can not be eliminated. We only try to ease its course. We prevent infectious complications together with anesthesiologists, which administer medication before surgery. Troughough desinfection of operative field and sterilisation of equipment also plays a role. Each bodily system has predisposition to different complications. I have described here most common ones and the metodes used to prevent them
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Perinatal morbidity and its prevention
Kohoutková, Barbora ; Velebil, Petr (advisor)
Within the perinatal period, the mother and the fetus exposed complications that may jeopardize or adversely affect their life. The thesis is focused on maternal morbidity, from which I most impressed operative deliveries, particularly repeat cesarean (SC). SC has now become convenient and safe public awareness and way to bring a child into the world. But is it really so? Few people seem to think the risks for the next birth in women with a history of SC. The number of women mainly from the 80s has risen considerably, so I think that is a current topic and discussed.
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Non-pharmacological Treatment for Clients with Functional Disorders of the Motion System - the Root Joint Hypermobility
BUREŠOVÁ, Vendula
This thesis deals with research into the issues of functional disorders of the musculoskeletal system, especially with hyper-mobility of root joints. It consists of a theoretical and a practical section. The theoretical section describes the components of the musculoskeletal system, with special emphasis on anatomy and basic kinesiology of root joints. The definitions of functional disorders, as well as a comparison with structural disorders, are also be given here. The conclusion of this section is devoted to hyper-mobility and a description of its history, aetiology, etiopathogenesis, and clinical manifestation. A classification of hyper-mobility, as well as diagnostics and differential diagnostics, are also included here. The theoretical section aims to describe the problems associated with hyper-mobility and the diagnostic difficulties. The practical section of this thesis describes the research that applied the qualitative research method. The test group consists of two women of different ages who have been diagnosed with hyper-mobility in their root joints. Their therapy took place in the rehabilitation department of the Vltava Health Centre in České Budějovice. All three patients provided their case history, underwent preliminary kinesiological analysis and verification of hyper-mobility. On the basis of this, the most effective individual therapy was designed and performed, which was originally the aim of this practical section. The therapy was verified through a final kinesiological examination which provided the grounds for the final evaluation of results.This thesis can offer a comprehensive view on the problems of hyper-mobility and the associated symptoms. It emphasises the fact that hyper-mobility should be taken into account and should not be ignored, which has often been the case up to now. The work can also serve as a source of inspiration when designing a rehabilitation plan for hyper-mobile patients.
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Suggestion of a strategy of a small and medium sized company in the area of consumer electronics
Švancara, Miroslav ; Šlechtová, Jitka (advisor) ; Bečvář, Martin (referee)
In the theoretical part, small and medium sized companies are described. In the analytical part, K+B Expert company was introduced by the author, as well as its competition. K+B Expert focuses on consumer electronics. It has 19 stores in the Czech republic -- it was a decision based on the strategic plan to expand its activities in the consumer electronics market in the horizontal network. The author chose Carlsbad region according to the situational analysis. A brand new store was to be created there, so all investment steps needed to be taken to set up a plain store, that needed to be supplied with all the necessary stock into the prepared racks and shelves. A marketing campaign followed together with the opening of the new store. K+B Expert used the marketing concept of its mother company network -- Expert CR. The marketing experts analyzed the effectiveness of several marketing tools. Leaflet was chosen as the most effective, since 55% of the survey respondents stated leaflet was the most effective in discovering that a new electronics store is to be opened. There were also advertisements on radio, on billboards and in newspapers. The cost of this marketing campaign exceeded the plan (the real cost was 836,500 CZK), it attracted more visitors than expected (a total of 8.560 visitors were attracted by the campaign). This has also impacted the sales, as the revenues were 9% higher than expected (totaled 4.36M CZK). Overall, the opening of the new store was a success and K+B Expert, s.r.o. can now look for a new region to expand with their activities.
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Current political issues of international trade related to the development of sub-Saharan Africa
Rejtharová, Denisa ; Volenec, Otakar (advisor) ; Kochan, Jan (referee)
The thesis deals with processes that are under way on the international political scene focused on bringing about change in international trade rules. The aim is to analyze to what extent are taken into account interests and development needs of sub-Saharan Africa. Examination of links between international trade on one hand, and development and poverty alleviation on the other hand, has emerged as one of the top issues of development studies. They consider a more substantial integration of sub-Saharan Africa countries into flows of international trade as one of the forms of efficient support to the African development efforts. Actually, two key trade negotiations are taking place -- the Doha Development Agenda under the auspices of the World Trade Organisation, and the Economic Partnership Agreements negotiations between the European Union and the ACP countries. The negotiations have proven to be politically sensible and up to now have failed in reaching an agreement. The present thesis seeks, therefore, to explore the reasons for the failure.
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