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Viscometric study of L-Lysine- and 6-aminocaproic acid-hyaluronan systems behavior within the range of low aminoacids concentrations
Šimáčková, Marcela ; Běťák, Jiří (referee) ; Chytil, Martin (advisor)
This bachelor thesis investigates the interaction between high-molecular weight hyaluronic acid (1.75 MDa HA) and amino acids, particularly lysine and 6-aminocaproic acid. The interactions should occur between the carboxyl groups of HA carrying a negative charge and a positive charge located on the nitrogen atom of the protonated amino acids. The presence of these interactions would mean the possibility of establishing bioactive compounds, e.g. drugs, on hyaluronic acid, in which it would act as a targetting carrier. The interactions were examined at low concentrations for both aminoacids, i.e. below 10 mmoldm-3, and for 6-aminocaproic acid also at high aminoacid concentrations, i.e. above 20 mmoldm-3. The presence of interaction was investigated using not only rheology, but also by measuring pH and conductivity. Based on this research, the interactions manifested in terms of a decrease in the system viscosity.
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Revitalization of Film studios in Zlín
Kolbábková, Martina ; Kopáčik,, Gabriel (referee) ; Sátora, Josef (advisor)
The thesis is focused on the revitalization of the Zlín film studios, with maximum respect for the principles of the investor, using the area in the long term. Idea thesis consists in consolidating the roots of film history, familiarity with film themes and issues for every generation. It also ensures that the area live 24 hours a day. For this reason, in the area of proposed areas not only public facilities, manufacturing, sport but also areas for housing. Campus should become a place where everyone would like to return, whether for entertainment, recreation, leisure and entertainment
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Statistical characteristics of the traffic flow microstructure
Apeltauer, Jiří ; Nagy,, Ivan (referee) ; Kumpošt,, Petr (referee) ; Holcner, Petr (advisor)
The actual traffic flow theory assumes interactions only between neighbouring vehicles within the traffic. This assumption is reasonable, but it is based on the possibilities of science and technology available decades ago, which are currently overcome. Obviously, in general, there is an interaction between vehicles at greater distances (or between multiple vehicles), but at the time, no procedure has been put forward to quantify the distance of this interaction. This work introdukce a method, which use mathematical statistics and precise measurement of time distances of individual vehicles, which allows to determine these interacting distances (between several vehicles) and its validation for narrow densities of traffic flow. It has been revealed that at high traffic flow densities there is an interaction between at least three consecutive vehicles and four and five vehicles at lower densities. Results could be applied in the development of new traffic flow models and its verification.
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User Interface for Work with Computer in Virtual Reality
Pazdera, Michal ; Najman, Pavel (referee) ; Beran, Vítězslav (advisor)
This thesis explores various ways of controlling computer in virtual reality. The aim of this thesis is to create a user interface which would allow the user to control computer in virtual reality. First it explores the possibilities of detecting users actions using sensors and its usability for controls and various interaction techniques in virtual reality. Based on the information gathered about the described topics it focuses on various ways of interactions using hands as controllers. This thesis tackles the issue of selecting and manipulating virtual objects. It introduces the design of three interaction techniques, which are then tested and evaluated.
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Design of experiments for quality optimization
Havlásek, Radim ; Kosina, Petr (referee) ; Novotný, Radovan (advisor)
This thesis is aimed to Design of Experiments methodology. Main purpose of this thesis is to create detailed materials for lessons of Design of Experiments in Quality Control courses. Thesis contains case studies which are applicable for education purposes. Design of Experiments has been applied for solder joints quality evaluation. Solder joints have been modeled in software ANSYS and finite element method has been applied for thermomechanical stress evaluation.
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Robot Interaction with Virtual Objects
Fisla, Jakub ; Španěl, Michal (referee) ; Materna, Zdeněk (advisor)
The goal of this bachelor's thesis was to create an aplication for robotic operating system ROS, adding virtual objects to data provided by the robot sensors. The theoretical part analyses the simulation techniques which combine real measured data with virtually generated data and explore equipment for data reading. The thesis designs a structure of feasible solution the application with respect to ROS platform and describes the application implementation. Finally, the focus is on testing of the application and thought about feasible extension this solution.
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Comparative study of interaction between surfactant and hyaluronan and different polyelectrolytes.
Stiborský, Filip ; Pravda,, Martin (referee) ; Pekař, Miloslav (advisor)
In this diploma thesis, the interactions between polyelectrolyte and surfactant at low and also at high concentration were studied. There was used pyrene as fluorescent probe during the fluorescence spectroscopy measurement, a cationic surfactant cetyltrimethylammonium bromide and as a main polyelectolyte has been chosen sodium polystyrene sulfonate at 1 MDa molecular size. In the medium containing 0.15 M NaCl we could observed a creation of the complexes – precipitates in the surrounding of CMC concentration and behind of this concentration. In the mixtures containing sodium polystyrene sulfonate and hyaluronan together, there was stronger tend to keep aggregation properties of sodium polystyrene sulfonate during difference concentration ratios. Beyond CMC concentration, hyaluronan starts to influence the aggregation properties of the system as well.
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Interaction Device for Augmented Reality
Pavlenko, Peter ; Kapinus, Michal (referee) ; Beran, Vítězslav (advisor)
This master thesis explores interactive augmented reality. The aim is to design, create andtest device, which allows interaction between user and augmented reality. First analyzesaugmented reality, devices for its displaying and necessary calibration methods. Then, onthe basis of acquired knowledge, shows design and construction of few prototypes of devicelike this. Finally it shows experiments to test correctness of the concept.
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Mutual interaction of multiple cracks growing in the particulate composite with brittle matrix under conditions of sub-critical crack growth
Slávik, Ondrej ; Ševeček, Oldřich (referee) ; Majer, Zdeněk (advisor)
In the first part of the submitted diploma thesis, the knowledge in the sphere of the fracture mechanics, related to the practice part of this thesis are summarized. In that the 2D parametrical numerical model of the particle composite with multiple cracks was created, using the finite elements method. Thanks to this model it is possible to find specific configurations which are showing the existance of multiple mutual interactions between these cracks, just by simple manipulation of the input data. In the calculations the influence of the residual stresses was considered which are formed during production of the material. The effect of the subcritical crack growth was taken into account as well in this thesis.
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Interaction Between Hyaluronan and Amphiphilic Molecules
Venerová, Tereza ; Burget, Ladislav (referee) ; Čeppan, Michal (referee) ; Pekař, Miloslav (advisor)
This work is focused on interaction between hyaluronan (Hya) and amphiphilic molecules. Using fluorescent probes method were carried out screening of the interaction of various surfactants with Hya. For further examination was chosen cetyltrimethylammonium bromide (CTAB). Interactions in this system have also been studied using fluorescence correlation spectroscopy (FCS), and additionally were performed initial tests of the cytotoxicity of the system. As an alternative CTAB were also used hydrophobically modified amino acids. Results showed their self-aggregation, but their interactions with hylauronanem was not as strong as with CTAB. The interaction of gel systems Hya-CTAB have also been studied, and was found to contain a hydrophobic domain capable solubilize hydrophobic substance. Thermogravimetric have been established that are able to contain up to 98% wt. water and rheologically were characterized their mechanical properties. These are tunable due to molecular weight (MW) of the hyaluronate. With increasing value of MW increases mechanical strength of the gel and decreases its fluidity.
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