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The needs of the ICU patient after myocardial infarction requiring V-A ECMO support
Procházková, Tereza ; Konopásková, Marie (advisor) ; Pražáková, Zuzana (referee)
Introduction: The coronary heart disease is still an actual topic. The mortality has been in recent years declining, but prevalence in the population stagnates, so involve a large group of patients. The incidence of acute myocardial infarction is still high. One of the methods of reperfusion therapy is the cardiac surgery by coronary artery bypass graft, which may be postoperatively complicated by the development of low cardiac output syndrome with the need of the extracorporeal membrane oxygenation. These patients require very specialized not only during the critical phase, but also during the long-term convalescence including rehabilitation, weaning from the artificial lung ventilation, self-sufficiency training and help with return to normal life. Literature search: The theoretical part is based on the research of National Medical Library (NLK) and Study and Scientific Library of the Pilsen Region (SVKPL). The PubMed, Scopus, Web of science and Science direct databases were used to search articles in professional publications, including the latest cohort studies. The periodicals Cor et Vasa, the European Heart Journal, Critical Care and the European Journal of Cardiovascular Nursing were used. An important source of information is the guidelines of the Czech Society of Cardiology (ČKS), European...
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The role of a diet in the prevention and treatment of cardiovascular diseases and evaluation of eating habits of patients with heart attack
Jakešová, Andrea ; Tůmová, Eva (advisor) ; Šišková, Ivana (referee)
This diploma thesis deals with the role of nutrition in the prevention and treatment of cardiovascular diseases. The theoretical part describes basic knowledge about cardiovascular diseases, prevalence, risk factors and the importance of nutrition in their prevention and treatment. The theoretical part describes in detail the effect of intake of carbohydrates, fiber, describes the role of glycemic index of foods, fat intake and their chemical composition, minerals, alcohol and coffee. One part of the theoretical part also describes the role of nutrition in the treatment. The research part is devoted to the dietary habits of patients who have already had an acute myocardial infarction. The aim of the research is to find out whether patients follow current recommendations for the prevention and treatment of CVD, or how the actual diets of these patients differ from recommendations. The data were collected using a questionnaire filled in during interviews with selected patients. It was found out that patients hospitalized for acute myocardial infarction have insufficient knowledge to build a balanced diet, or that nutritional recommendations are consciously violated. Problematic is especially the choice of fats, the unbalanced composition of the diet, the frequent consumption of too fat and sweet...
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Automatic detection of myocardial infarction in ECG
Nejedlý, Lukáš ; Kozumplík, Jiří (referee) ; Smíšek, Radovan (advisor)
This master’s thesis deals with the automatic detection of myocardial infarction in ECG. Semester work consists of two parts. The theoretical part provides a description of the electrical conduction system of the heart, spreading of electrical activity through the heart muscle, the methods of ECG scanning and the ECG curve. There are also mentioned the causes of myocardial ischemia and various methods of its detection. Another part is devoted to high-frequency ECG, analysis of HFQRS and clinical studies which describe the use of high-frequency ECG in diagnosis of myocardial infarction. In the practical part is proposed an algorithm using low-frequency components ECG and an algorithm using high-frequency components ECG for automatic detection of myocardial infarction. The proposed algorithms are implemented in programming environment MATLAB and tested on signals from the PTB database. The final part of the master‘s thesis is devoted to the comparison of the success of myocardial infarction by means of low frequency and high frequency components of ECG and comparison of achieved results with results from clinical studies.
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Insurance of serious illnesses
Rezek, Vojtěch ; Ducháčková, Eva (advisor) ; Černochová, Martina (referee)
This bachelors thesis deals with the insurance of serious illnesses and its significance in the insurance market in the Czech Republic. Firstly, the thesis outlines the basic characteristics of this insurance and the types of serious illnesses it covers. In addition, the history of the development of this type of insurance in the world insurance market and its use in the Czech environment is briefly discussed. Furthermore, this dissertation lists the technical parameters of the insurance in the insurance contract and their practical utilization. Moreover, the specifics of the most serious illnesses from multiple expert perspectives are discussed, followed by examining the modern trends in this insurance policy. The second part of this thesis analyses statistical data on the number of diagnoses and deaths of serious illnesses in a given period of time, thus determining the frequency of these illnesses. Additionally, state financial support in cases of serious illnesses is discussed. The thesis concludes with the calculations of the insurance premiums in serious illness insurance, comparing different insurers and the amount of indemnity in the given period. The aim of this dissertation is to analyse the statistical data concerning the insurance of serious illnesses, affirming the importance of obtaining insurance of this health risk in life insurance contracts on the basis of the analysis carried out in the practical part of the thesis.
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Casuistics of physiotherapy care for patient diagnosed with cerebellar lesion after a brain hypoxia
Vyhnánek, Štěpán ; Reckziegelová, Petra (advisor) ; Křížková, Štěpánka (referee)
Title: Casuistics of physiotherapy care for patient diagnosed with cerebellar lesion after a brain hypoxia Goal: The goal of this work is data collection and processing of theoretical information on cerebellar ischemia and a preparation of casuistics of a patient with cerebellar hypoxia after heart attack. Summary: My thesis deals with cerebellar hypoxia after leaving sufferd from loss of heart as a result of heart attack. Thesis is divided in to parts. The first part, a theoretical one, describes anatomical and functional structure of the cerebellum, a brief description of ISCH and treatment options. This part also contains a description of rehabilitation methods used in patients with cerebellar syndrome. The second part of my thesis, a practical one, is focused on a precise description of the work with the patient after having suffered from loss of cerebellar hypoxia, I have collaborated with on inpatient department of regional hospital in Kladno from January 5th to January 22nd, 2016. The practical part contains results of patient's examination in time of admision to hospital and in time of release from hospital and a description of individual therapautical units (used methods, the progress of the therapy and the success of treatment). Keywords: heart attack, cerebellum, rehabilitation
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Genetic and Proteomic Screening in Patients with Cardiovascular Disease.
Boháčová, Jana
The aim of this study is to analyse a genetic and proteomic aspects that could play an important role in development of chosen cardiovascular disease. Matrix metalloproteinases are enzymes that contribute strongly to the degradation of extracellular matrix components. In this study the serological levels of MMP-2 and MMP-9 were investigated using immunological testing in patients with aortic valve disease and in patients with myocardial infarction. Significantly higher levels of MMP-2 and MMP-9 were determined in both above mentioned groups of patients. Association of serum levels of MMP-2 and MMP-9 and development of concomitant aortic dilatation was not confirmed in patients with aortic valve disease. Changes in serum levels within 24 hours and after 6 months post myocardial infarction were characterized. About 10 % of patients operated for aortic valve disease suffer simultaneously from ascending aortic dilatation. The current study did not reveal any significant genetic variation in TGFBR2 gene and in chosen exons of FBN1 gene in these patients. Further genetic research is needed to identify the cause of the pathology in aortic wall. Gene expression of selected genes was measured by microarray screening in patients with myocardial infarction. These genes were related to MMPs and did not show...
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Genetic and Proteomic Screening in Patients with Cardiovascular Disease.
Šímová, Jana ; Škvor, Jiří (advisor) ; Gregor, Pavel (referee) ; Čurila, Karol (referee)
The aim of this study is to analyse a genetic and proteomic aspects that could play an important role in development of chosen cardiovascular disease. Matrix metalloproteinases are enzymes that contribute strongly to the degradation of extracellular matrix components. In this study the serological levels of MMP-2 and MMP-9 were investigated using immunological testing in patients with aortic valve disease and in patients with myocardial infarction. Significantly higher levels of MMP-2 and MMP-9 were determined in both above mentioned groups of patients. Association of serum levels of MMP-2 and MMP-9 and development of concomitant aortic dilatation was not confirmed in patients with aortic valve disease. Changes in serum levels within 24 hours and after 6 months post myocardial infarction were characterized. About 10 % of patients operated for aortic valve disease suffer simultaneously from ascending aortic dilatation. The current study did not reveal any significant genetic variation in TGFBR2 gene and in chosen exons of FBN1 gene in these patients. Further genetic research is needed to identify the cause of the pathology in aortic wall. Gene expression of selected genes was measured by microarray screening in patients with myocardial infarction. These genes were related to MMPs and did not show...
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