National Repository of Grey Literature 13 records found  previous11 - 13  jump to record: Search took 0.00 seconds. 
Effect of cannabis in sports training
Yücel, Yalın ; Tufano, James Joseph (advisor) ; Šteffl, Michal (referee)
Title: Effect of cannabis in sports training. Objectives: * Present the physiological and psychological effects of cannabis on human body. * Identify harmful and beneficial effects of cannabis consumption in people who partake in recreational sporting activities as well as competitive athletes. * Identify the perception of cannabis use in the sports world. Methods: * Detailed literature research on cannabis and its primary components. * Literature research on scientific requirements of sports training. * Systematic review of previous surveys and experiments regarding the effects of cannabis on sports exercise parameters. * Preparing a questionnaire for sportspeople (current and former Turkish and Czech American football players in general) and analyzing the results. Results: * There hasn't been many recent scientific research about the specific effects of cannabis ingestion in sports performance. * There are some beneficial attributes of cannabis in sport training as well as performance hindering attributes and potentially dangerous side effects. * Questionnaire participants generally do not think cannabis is a performance- enhancing substance. * There exists contrary opinions, beliefs and scientific evidence on almost all of the aspects of cannabis and its use in sport. Keywords: cannabis, sport,...
The role of cannabinoid system in neurobiology and therapy of psychotic disorders - an experimental study in animal models of psychosis
Nováková, Pavlína ; Páleníček, Tomáš (advisor) ; Šustková, Magdaléna (referee)
Throughout the scientific world the topic of cannabis usage and its link with psychosis seems to be discussed intensively. Considering the fact that the Czech Republic is a country with one of the highest prevalence of cannabis usage in the world it becomes a sensitive issue even in our circumstances. In the theoretical part of the work we attempted to review current knowledge of a link between cannabinoid system, canabis usage and psychosis and to point out possible future therapeutic potential of cannabinoids in the treatment of psychotic diseases. In the practical part of the work we focused on verification of propsychotic features of THC in animal model with particular attention to validation of acute subcutaneous admonistration of this drug as a novel cannabinoid model of psychosis. At the same time we tried to elucidate antipsychotic effect of CBD in this model. We tested these hypotheses in two behavioral tests (open field test, PPI ASR) and electrophysiologically (quantitative EEG). The whole analysis is enriched with pharmacokinetic data from subcutanneous and oral administration of cannabinoids. Powered by TCPDF (www.tcpdf.org)
Selection of cannabis chemotypes suitable for therapeutic use with predominant active substance THC
Michnová, Lenka ; Fraňková, Adéla (advisor) ; Klouček, Pavel (referee)
During recent years the possible medical application of cannabis has been discussed more and more. It turns out, that the active substances (cannabinoids cannabidiol and tetrahydrocannabinol) have a significant potential in medicine and do not have to be only misused as a recreational drug. The Department of Crop Production (Faculty of Agrobiology, Food and Natural Resources) is the first institution with granted permission to legally cultivate cannabis, with higher THC content than 0,3 %, for research purposes. The first part of literate review recapitulates the basic knowledge about the cannabis, its biologically active substances and current legislation. The second part describes the endocannabinoid system and utilization of cannabis in the field of medicine. This thesis aims to evaluate the THC and CBD content in seven different cannabis cultivar strains (Nurse Jackie, Conspiracy Kush, Jillybean, Jack Cleaner 2, Jack Skellington, Nordle and National Health Service). The cannabis plants were cultivated in three cultivation cycles. The content of active substances in dried and homogenised inflorescence was analysed by gas chromatography with flame ionization detection (GC-FID) according to UN methodology. Based on the analysis, the appropriate genotypes were chosen, which are in accordance of Regulation 236/2015 Sb. and needs of the patients. According to results it was found, that all seven analysed cultivars are suitable for medical utilization regarding the content of THC and CBD. The highest average content of THC was measured by cultivar Jack Cleaner 2. On the other hand, the lowest THC content was established by cultivar Nordle. It was demonstrated, that the differences in THC content are connected rather to genotype variation than cultivation factors. The main goal of the thesis was to discover which of the seven cultivars will be stable regarding not only THC and CBD content, but also the crop yield. In those regards the research shows the cultivar Jack Cleaner 2 and Nurse Jackie as the most suitable. Preliminary results indicate that these two cultivar strains would be the most suitable for the therapeutic purposes.

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