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Study of Process Control in Selected Products
Růžička, Pavel ; Bednář, Josef (referee) ; Jurová, Marie (advisor)
The thesis focuses on the process of production of castings in the company ŽĎAS, a.s. and its methods for implementing customer's requirements. The goal was to create a Work Flow diagram of technical preparation of production based on the company's internal directives. The next step was to compare it with the actual situation represented by a case job and to make a conclusion. The customer's requirements for the case production order included increased level of control and purchasing weld-on parts. The incorporation process for these requirements was not described by the original Work Flow and was the subject of its new revision. For its better practical application the Study contains business and organizational structures of ŽĎAS, a.s.
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Comparison of advanced analysis of fMRI data from oddball experiment
Fajkus, Jiří ; Jan, Jiří (referee) ; Provazník, Ivo (advisor)
This master´s thesis deals with processing and analysis of data, acquired from experimental examination performed with functional magnetic resonance imaging technique. It is an oddball type experimental task and its goal is an examination of cognitive functions of the subject. The principles of functional magnetic resonance imaging, possibilities of experimental design, processing of acquired data, modeling of a response of organism and statistical analysis are described in this work. Furthermore, particular parts of preprocessing and analysis are carried out using real data set from experiment. The main goal of this work is suggestion and realization of model, which enables advanced categorization of stimuli, considering the type of previous rare stimulus and the number of frequent stimuli within them. With its in-depth categorization, this model enables detail exploration of cerebral processes, associated mainly with attention, memory, expectancy or cognitive closure. The second point of that work is an evaluation of models of hemodynamic response, which are applied in statistical analysis of data from fMRI experiment. Comparison of basis functions, the models of hemodynamic response to experimental stimulation used for general linear model, is performed in this work. The result of this comparison is an evaluation of detection efficiency of activated voxels, false positivity rate and computational and user difficulty.
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The assesment of chloramphenicol residues in biological material, water and feed by GC/MS
Lukačková, Dagmar ; Šalplachta, Jan (referee) ; Rejtharová, Martina (advisor)
This diploma thesis addresses the presence and determination of chloramphenicol residues in biological materials. The theoretical part presents the literature retrieval containing information about veterinary medicaments with the banned use in food producing animals and also the sum of the legislative requirements concerning the presence of these substances in foodproducts and raw food materials of animal origin. The comparison was carried out between the existing analytical methods used for the determination of chloramphenicol residues in different biological materials, which are altogether based on the solid phase extraction for the extract cleaning and the new procedures for sample preparations using columns where the sorbent performs on the molecularly imprinted polymers principle.
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Study of mitochondrial processing peptidases in procyclic \kur{Trypanosoma brucei}
POLIAK, Pavel
Aim of this work was to find out how mitochondrial processing peptidases are working in the mitochondrion of Trypanosoma brucei. I have shown by RNA interference that mitochondrial processing peptidase (MPP) and mitochondrial intermediate peptidase (MIP) are essential for procyclic stages. Moreover, processing of human frataxin in T. brucei has a similar pattern as in human cells.
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