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National Repository of Grey Literature

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	The simulation of effect of membrane channel block by propafenone on electrical activity on human atrial cells Brožková, K. ; Pásek, Michal ; Šlichta, J. The main aim of this study is to explore the effect of propafenone on suppression of irregular excitations in human atrial cell. A program was designed that contains the computational model of electric activity on human atrial cells and the mathematical model of interaction of propafenone with INa-channels. This integrated model can served for simulations of the drug effects. Detailed record
	Mathematical modelling of restitution processes in cardiac cells Pásek, Michal ; Šimurda, J. The restitution processes in cardiac cells are difficult to analyse experimentally. An effective approach to their quantitative analysis is mathematical modelling. The quantification of the share of individual membrane channels in restitution processes is based on the evaluation of electrical charges transmitted across cellular membrane. Detailed record
	Recovery of action potential of cardiac cell after preceding excitation Šimurda, J. ; Šimurdová, M. ; Pásek, Michal ; Bravený, P. Based on experimental data and computer modelling, a novel method of assessment the electrical restitution in cardiac tissue is suggested. The crucial parameter is the electric charge, which unlike the instantaneous value of current allows quantifying the share of underlying current components. Detailed record
	ATP senzitive potassium current in rat ventricular myocytes (the effect of antiarrythmic drugs) Pásek, Michal Detailed record
	Qauntitative modelling of physiological processes in the cardiac Pásek, Michal Detailed record

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