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Population Characteristics in Forensic Genetics
Faltus, Václav
The aim of this paper is to present some methods used in forensic genetics. Forensic genetics is only one part of a wide spectrum of sciences called forensics. It includes identification of victims of natural disasters, mass transportation accidents and industry accidents. It also includes identification of offenders of a crime and determination of paternity. Our current work involves analysis of the genetic data from the Czech population. Therefore and in concordance with other international studies, we focus on methods used in analysis of the genetic profiles of the STR (short tandem repeat) polymorphisms.
Fulltext: content.csg -  PDF
Plný tet: 0373341 - PDF
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Computational Systems for Selection and Priorization of Candidate Genes that Underlie Human Hereditary Disease
Adášková, Jana
The aim of this paper is to present an overview of six independent computational methods for the selection and prioritization of candidate genes for human diseases and, rather than selecting a best method, to offer the prospective user a better understanding of the inputs, outputs and functionality of each available method. A survey of these methods also offers the bioinformatics community an opportunity to assess the efficacy of current computational approaches to disease gene identification, and informs future directions for research in this field.
Fulltext: content.csg - PDF
Plný tet: 0373338 - PDF
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