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Characterization of microwave plasma jet generated in argon-nitrogen mixtures
Truchlá, Darina ; Mazánková, Věra (oponent) ; Krčma, František (vedoucí práce)
This thesis is concerned with influence of nitrogen admixture to non-thermal microwave plasma jet generated in argon flow at atmospheric pressure. Non-thermal plasma can be used in more biomedical applications such cancer treatment, blood coagulation, sterilization etc. It is necessary to know the changes of plasma composition and its parameters in dependence nitrogen concentration to avoid potentional damages of the treated tissue. Plasma jet was characterized by optical emission spectroscopy along its axis. Electron, vibrational and rotational temperatures were calculated from intensities of the selected spectral lines and bands emitted by particles generated in plasma. The results show increase of the nitric oxide concentration followed by the increase UVC radiation. Temperature of the neutral gas increase too, but not so much and thus jet with nitrogen addition can be still used for the treatment of thermosensitive materials such as human tissue. Study of the sterilization effect of microwave plasma generated in argon-nitrogen mixtures is still under progress. Some of the results obtained during this thesis were included in the paper submitted into Journal of Physics D: Applied Physics.
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Characterization and application of microwave plasma on wound healing
Truchlá, Darina ; Němcová, Andrea (oponent) ; Krčma, František (vedoucí práce)
Non-thermal plasma has a lot of ways for using in nowadays medicine. It presents many useful actions like charged particles, UV light, electric field, radicals, excited atoms and molecules. That complicated chemistry directs to uncountable synergistic interaction between cold plasma and biological systems, involve cells and tissues. This thesis is about effects of cold plasma to wound healing. Two different microwave plasma systems were used for the presented study. The first one was argon plasma torch generated by surface wave using the quartz capillary, the second one was plasma torch with reverse vortex argon flow. Diagnostics of plasma jet by optical emission spectroscopy shown the presence of active particles, which are responsible for a lot of impact of plasma treatment. Concentrations of active particles generated by plasma are dependent on conditions of plasma generation like power of generator and gas flow. For visual evidence of effects on skin caused by active particles was created simulation of skin tissue. Interaction between plasma jet and artificial skin tissue shown that UV light and temperature are not responsible for all observed effects which are noticed after plasma treatment. Some part of experiments was realized in collaboration with Medical University of Sofia in Bulgaria. The theory of positive effect to wound healing was supported by experiments based on treating artificially created wounds on laboratory mice by cold plasma. It was proved, that process of wound healing is significantly shorter after using plasma treatment in comparison with normal wound healing. Plasma treating of wound for 10 seconds in two consequent days seems like more effectively than application of plasma only one day. This Thesis was carried out as a part of international project PLASMABORDER that was supported by European commission under cohesion funds; programme INTEREG SK-CZ under contract No. 304011P709.
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Characterization and application of microwave plasma on wound healing
Truchlá, Darina ; Němcová, Andrea (oponent) ; Krčma, František (vedoucí práce)
Non-thermal plasma has a lot of ways for using in nowadays medicine. It presents many useful actions like charged particles, UV light, electric field, radicals, excited atoms and molecules. That complicated chemistry directs to uncountable synergistic interaction between cold plasma and biological systems, involve cells and tissues. This thesis is about effects of cold plasma to wound healing. Two different microwave plasma systems were used for the presented study. The first one was argon plasma torch generated by surface wave using the quartz capillary, the second one was plasma torch with reverse vortex argon flow. Diagnostics of plasma jet by optical emission spectroscopy shown the presence of active particles, which are responsible for a lot of impact of plasma treatment. Concentrations of active particles generated by plasma are dependent on conditions of plasma generation like power of generator and gas flow. For visual evidence of effects on skin caused by active particles was created simulation of skin tissue. Interaction between plasma jet and artificial skin tissue shown that UV light and temperature are not responsible for all observed effects which are noticed after plasma treatment. Some part of experiments was realized in collaboration with Medical University of Sofia in Bulgaria. The theory of positive effect to wound healing was supported by experiments based on treating artificially created wounds on laboratory mice by cold plasma. It was proved, that process of wound healing is significantly shorter after using plasma treatment in comparison with normal wound healing. Plasma treating of wound for 10 seconds in two consequent days seems like more effectively than application of plasma only one day. This Thesis was carried out as a part of international project PLASMABORDER that was supported by European commission under cohesion funds; programme INTEREG SK-CZ under contract No. 304011P709.
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Characterization of microwave plasma jet generated in argon-nitrogen mixtures
Truchlá, Darina ; Mazánková, Věra (oponent) ; Krčma, František (vedoucí práce)
This thesis is concerned with influence of nitrogen admixture to non-thermal microwave plasma jet generated in argon flow at atmospheric pressure. Non-thermal plasma can be used in more biomedical applications such cancer treatment, blood coagulation, sterilization etc. It is necessary to know the changes of plasma composition and its parameters in dependence nitrogen concentration to avoid potentional damages of the treated tissue. Plasma jet was characterized by optical emission spectroscopy along its axis. Electron, vibrational and rotational temperatures were calculated from intensities of the selected spectral lines and bands emitted by particles generated in plasma. The results show increase of the nitric oxide concentration followed by the increase UVC radiation. Temperature of the neutral gas increase too, but not so much and thus jet with nitrogen addition can be still used for the treatment of thermosensitive materials such as human tissue. Study of the sterilization effect of microwave plasma generated in argon-nitrogen mixtures is still under progress. Some of the results obtained during this thesis were included in the paper submitted into Journal of Physics D: Applied Physics.
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