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Národní úložiště šedé literatury Nalezeno 2 záznamů.  Hledání trvalo 0.00 vteřin. 
Detection of DNA/RNA fragments using graphene sensor and influence of upper electrolytic gate
 Herzánová, Kristína ; Konečný, Martin (oponent) ; Bartošík, Miroslav (vedoucí práce)
Graphene's unique properties, such as biocompatibility, high charge carrier mobility and surface sensitivity, make it a suitable material for biosensing devices. This thesis aims to describe and demonstrate such sensors and the measurements performed to detect fragments of DNA, specifically cytosine-based substances. The graphene is employed in field-effect transistors as the conductive sensing channel. The doping of graphene induced by adsorbed molecules on the channel causes changes in graphene's transport properties. These changes are reflected in electronic response measurements: real-time measurements of graphene sheet resistance responding to the addition of different solutions and dependency of the resistance on the continual change of gate voltage. The latter can be performed either in the back-gated or electrolytic top-gated configuration of the FET sensor. The difference between the two configurations is observed, as well as the effect of the distance between graphene and top-gate electrode on the sensor response. The output of these measurements are transfer curves exhibiting typical peaks indicating the charge neutrality point (Dirac point) of graphene. Different concentrations of the analyte solution results in different shift of the Dirac point voltage, quantifying the doping level.
Úplný záznam
Detection of DNA/RNA fragments using graphene sensor and influence of upper electrolytic gate
 Herzánová, Kristína ; Konečný, Martin (oponent) ; Bartošík, Miroslav (vedoucí práce)
Graphene's unique properties, such as biocompatibility, high charge carrier mobility and surface sensitivity, make it a suitable material for biosensing devices. This thesis aims to describe and demonstrate such sensors and the measurements performed to detect fragments of DNA, specifically cytosine-based substances. The graphene is employed in field-effect transistors as the conductive sensing channel. The doping of graphene induced by adsorbed molecules on the channel causes changes in graphene's transport properties. These changes are reflected in electronic response measurements: real-time measurements of graphene sheet resistance responding to the addition of different solutions and dependency of the resistance on the continual change of gate voltage. The latter can be performed either in the back-gated or electrolytic top-gated configuration of the FET sensor. The difference between the two configurations is observed, as well as the effect of the distance between graphene and top-gate electrode on the sensor response. The output of these measurements are transfer curves exhibiting typical peaks indicating the charge neutrality point (Dirac point) of graphene. Different concentrations of the analyte solution results in different shift of the Dirac point voltage, quantifying the doping level.
Úplný záznam

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