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Mathematical modeling of early embryogenesis processes
Dunajová, Michaela ; Šejnoha, Jiří (advisor) ; Drutovič, David (referee)
1 Abstract: Early embryogenesis is a fundamental phenomenon of developmental biology, which involves the establishment of the first structures within embryos. The work focuses on mathematical spatial models of mammalian blastulation, which were created based on spatial approach. We discuss and compare six mo- dels, which simulate the differentiation of cell lines and the formation of blas- tocyst structures. Models are based on local rules, using considerable cellular abstraction. Models focus on the processes of differentiation of the blastomere into the trophoectoderm and the inner cell mass, followed by the establishment of the structure of the epiblast and the primitive endoderm.

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1 Dunajová, Marie Bc.
1 Dunajová, Markéta
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