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Detection of interictal activity in long-term stereo-EEG recordings
Šikyňová, Soňa ; Králík, Martin (oponent) ; Smital, Lukáš (vedoucí práce)
In patients with pharmacoresistant focal epilepsy, complete prevention of the clinical manifestation of epilepsy is achievable through surgical removal of the epileptic zone. Accurate localization of the epileptic zone relies on the detection of interictal epileptic discharges, which serve as an essential tool. However, the effectiveness of automated interictal epileptic discharge detectors may be influenced by the patient's state of vigilance. This study demonstrates a statistically significant difference in performance between different detectors during different sleep phases. The precise temporal and spatial distribution of interictal activity holds paramount importance for identifying the epileptic zone. Inaccurate determination of the epileptic zone and unsuccessful resection can occur if the sensitivity and accuracy of detectors vary across sleep stages. Consequently, it is crucial to consider the patient's consciousness status when pinpointing the epileptic zone. One approach to address these variations in detector performance at different states of vigilance is to optimize the parameters of detection algorithms. This study includes an investigation into the optimized parameters for two interictal epileptic discharge detectors.

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