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Relationship between compensatory status and renal function in patients with diabetes mellitus type II
Vondráčková, Helena ; Szotáková, Barbora (advisor) ; Boušová, Iva (referee)
Charles University Faculty of Pharmacy in Hradec Králové Department of Biochemical Sciences Candidate: Mgr. Bc. Helena Vondráčková Supervisor: prof. Ing. Barbora Szotáková, Ph.D. Specialist consultant: MUDr. Pavel Pick Title of diploma thesis: Relationship between compensatory status and renal function in patients with diabetes mellitus type II Diabetes mellitus is a chronic disease accompanied by a number of complications. Among the most common and at the same time the most serious are kidney diseases, which often lead to their failure. These patients then rely on lifelong dialysis treatment or a possible kidney transplant. By compensating for diabetes mellitus effectively, the development of complications can be reduced or at least delayed. Fasting and postprandial blood glucose level and glycated hemoglobin are used to assess the state of compensation. The renal function is assessed by the examination of albumin and proteins in urine, serum creatinine concentration and estimation of glomerular filtration. The aim of the thesis was to determine whether there is a relation between the level of compensation for diabetes mellitus and the renal function. The data from 70 patients diagnosed with diabetes mellitus type II regularly checked in a diabetological clinic were evaluated. Samples were...
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Relationship between compensatory status and renal function in patients with diabetes mellitus type II
Vondráčková, Helena ; Szotáková, Barbora (advisor) ; Boušová, Iva (referee)
Charles University Faculty of Pharmacy in Hradec Králové Department of Biochemical Sciences Candidate: Mgr. Bc. Helena Vondráčková Supervisor: prof. Ing. Barbora Szotáková, Ph.D. Specialist consultant: MUDr. Pavel Pick Title of diploma thesis: Relationship between compensatory status and renal function in patients with diabetes mellitus type II Diabetes mellitus is a chronic disease accompanied by a number of complications. Among the most common and at the same time the most serious are kidney diseases, which often lead to their failure. These patients then rely on lifelong dialysis treatment or a possible kidney transplant. By compensating for diabetes mellitus effectively, the development of complications can be reduced or at least delayed. Fasting and postprandial blood glucose level and glycated hemoglobin are used to assess the state of compensation. The renal function is assessed by the examination of albumin and proteins in urine, serum creatinine concentration and estimation of glomerular filtration. The aim of the thesis was to determine whether there is a relation between the level of compensation for diabetes mellitus and the renal function. The data from 70 patients diagnosed with diabetes mellitus type II regularly checked in a diabetological clinic were evaluated. Samples were...
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Glycated hemoglobin: one of the indicators of compensation Diabetes mellitus
Vondráčková, Helena ; Raisová Stuchlíková, Lucie (advisor) ; Boušová, Iva (referee)
Diabetes mellitus belongs to the chronic civilization diseases with increasing inter-incidence. This Disease is connected with numerous complications that increase patients mortality and morbidity. The aim of the cure is to compensate and delay the development of especially late complications of diabetes. The bachelor thesis is focused on glycated hemoglobin, which is currently considered the primary method in evaluation of the diabetes mellitus compensation. The theoretical part is focused on basic characteristics and associated complications with the attention paid to the evaluation of the disease compensation. The practical part is focused on methods of determination of glycated hemoglobin, relations among the patients' levels of glycated hemoglobin, average blood glucose and BMI. Key words: Diabetes mellitus, glycated hemoglobin, diabetic retinopathy, diabetic nephropathy, diabetic neuropathy.
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