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Adaptation mechanisms of the nervous system Following chronic injury and its clinical impact
Vaško, Peter ; Štětkářová, Ivana (advisor) ; Bojar, Martin (referee) ; Ehler, Edvard (referee)
Remarkable progress in therapy and diagnostics of neurological diseases, including brain and spinal cord injuries, has been achieved during last years. However, the nervous system with its complicated feedback circuits systems reaching from the periphery to the brain remains still unclear to our knowledge. Regeneration following serious injuries of the peripheral or central nervous system is often incomplete, leading to its poor functional outcome. Thus for the patients it means to become reconciled with a permanent disability. It is caused by limited recovery of the nervous system. Physiological circuits and neuronal nets are altered by an injury. In our study we try to elucidate some kind of an adaptation process of the peripheral and spinal nervous system using some of the neurophysiological methods. We studied the spinal inhibitory circuits and its afferent and efferent pathways and its role in acute and chronic lesions of the nervous system. We tried to reveal its potential capability in nervous system recovery. Our research includes several topics which have not been published yet. We focused on a spinal inhibitory reflex namely a cutaneous silent period in several conditions. In physiological conditions, we studied the influence of temperature on the cutaneous silent period; in pathological...
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Adaptation mechanisms of the nervous system Following chronic injury and its clinical impact
Vaško, Peter ; Štětkářová, Ivana (advisor) ; Bojar, Martin (referee) ; Ehler, Edvard (referee)
Remarkable progress in therapy and diagnostics of neurological diseases, including brain and spinal cord injuries, has been achieved during last years. However, the nervous system with its complicated feedback circuits systems reaching from the periphery to the brain remains still unclear to our knowledge. Regeneration following serious injuries of the peripheral or central nervous system is often incomplete, leading to its poor functional outcome. Thus for the patients it means to become reconciled with a permanent disability. It is caused by limited recovery of the nervous system. Physiological circuits and neuronal nets are altered by an injury. In our study we try to elucidate some kind of an adaptation process of the peripheral and spinal nervous system using some of the neurophysiological methods. We studied the spinal inhibitory circuits and its afferent and efferent pathways and its role in acute and chronic lesions of the nervous system. We tried to reveal its potential capability in nervous system recovery. Our research includes several topics which have not been published yet. We focused on a spinal inhibitory reflex namely a cutaneous silent period in several conditions. In physiological conditions, we studied the influence of temperature on the cutaneous silent period; in pathological...
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Framework comparison for Java unit testing
Vasko, Peter ; Pavlíčková, Jarmila (advisor) ; Pecinovský, Rudolf (referee)
Testovanie jednotiek zdrojového kódu, v tomto prípade tried programovacieho jazyka Java, je v dnešnej dobe súčasťou mnohých metodík vývoja software a jedným z predpokladov vytvorenia kvalitného programu. Nástroje uľahčujúce tento proces, čiže frameworky pre jednotkové testovanie a ich porovnanie, sú predmetom tejto práce. Vybrané boli konkrétne tieto: TestNG, JTiger a JUnit 4. Porovnanie prebieha na základe vopred definovaných kritérií. Vybrané nástroje, ktoré reprezentujú najkvalitnejšie a najpoužívanejšie frameworky, sú podrobne predstavené v samostatných kapitolách, kde sa kladie dôraz na ich konkrétne možnosti, implementované funkčnosti a špecifické prvky. Tie sú ilustrované na jednoduchých príkladoch. Samotné hodnotenie v závere práce v prvej časti porovnáva implementáciu spoločných funkčností, v druhej sa zameriava na špecifické prvky. U oboch skupín hodnotí kvalitu a pridanú hodnotu pre užívateľa daného nástroja.
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