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National Repository of Grey Literature

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	Nucleosid fosfonové kyseliny a odvozené oligonukleotidy: Strukturní diversita vs biologické vlastnosti Rosenberg, Ivan ; Barvík, I. ; Buděšínský, Miloš ; Kočalka, Petr ; Králíková, Šárka ; Liboska, Radek ; Pačes, Ondřej ; Páv, Ondřej ; Petrová, Magdalena ; Pohl, Radek ; Pressová, Martina ; Rejman, Dominik ; Votruba, Ivan ; Točík, Zdeněk This article deals with the biological and physico-chemical properties of both isopolar, isosteric and non-isosteric phosphonate nucleotides and oligonucleotides. Detailed record
	Nové nukleosidfosfonové kyseliny jako inhibitory thymidinfosforylázy Kočalka, Petr ; Rinnová, Markéta ; Vaněk, Václav ; Rejman, Dominik ; Votruba, Ivan ; Tomečková, Ivana ; Králíková, Šárka ; Petrová, Magdalena ; Páv, Ondřej ; Pohl, Radek ; Buděšínský, Miloš ; Liboska, Radek ; Točík, Zdeněk ; Rosenberg, Ivan Several sugar-modified thymine-containing nucleoside phosphonic acids were found as a strong inhibitors of thymidine phosphorylase purified from spontaneous T-cell lymphomas of an inbred Sprague-Dawley rat strain. Detailed record
	Isosterní fosfonátová internukleotidová vazba typu 3'-O-P-CH2-O-4'C: Cesta k dalším údajům o její stereochemii Točík, Zdeněk ; Barvík, I. ; Buděšínský, Miloš ; Rosenberg, Ivan Synthesis of model thymidine dinucleoside phosphonate containing 3´-O-P-CH2-O-4´C isosteric linkage in 13C-labelled form enabled its NMR conformational description which was further compared with MDS and ab initio studies. Detailed record
	From nucleoside phosphonic acids to modified oligonucleotides Rosenberg, Ivan ; Endová, Magdalena ; Králíková, Šárka ; Liboska, Radek ; Rejman, Dominik ; Točík, Zdeněk A number of new isopolar phosphonate nucleotide analogues were prepared and a large set of oligonucleotides containing structurally diverse modification internucleotide linkages could be created. Detailed record
	Isosteric phosphonate mono-and oligonucleotides originating from 4',5'-didehydronucleoside precursors: some synthetic possibilities and limitations Točík, Zdeněk ; Liboska, Radek ; Barvík, I. ; Buděšínský, Miloš ; Masojídková, Milena ; Kavenová, Ivana ; Rosenberg, Ivan The work deals with aspects of synthesis and properties of isosteric phosphonate analogs of 5'-monophosphates and with structure-properties relationship of the related oligothymidylates. Detailed record
	Chemistry of Nucleic Acid Components. 12th Symposium Točík, Zdeněk ; Hocek, Michal In keeping with the main goals of the well-established series, the main topics of the XII NAC symposium covered the synthesis, transformations, physical chemistry, and biological activity of nucleosides, nucleotides and oligonucleotides as well as the aspects of their molecular biology in the broader sense. Detailed record
	Crystal and solution structure of 5'-.I.O./I.-(guanosine-2'-.I.O./I.-phosphonomethyl)cytidine, an isopolar nonisosteric phosphonate analog of GpC Zachová, J. ; Císařová, I. ; Buděšínský, Miloš ; Liboska, Radek ; Točík, Zdeněk ; Rosenberg, Ivan Detailed record
	Synthetic route to novel isosteric phosphonate analogs of oligonucleotides Točík, Zdeněk ; Kavenová, Ivana ; Rosenberg, Ivan Detailed record
	Synthesis and hybridization properties of isopolar, nonisosteric phosphonate-based homooligonucleotides Rejman, Dominik ; Liboska, Radek ; Endová, Magdalena ; Kavenová, Ivana ; Točík, Zdeněk ; Rosenberg, Ivan Detailed record
	Preparation of 4'-Phosphonomethoxy Derivatives of Nucleosides: Addition of Hydroxymethanephosphonic Acid Dialkyl Esters to 4',5'-Didehydronucleosides Točík, Zdeněk ; Kavenová, I. ; Rosenberg, Ivan Detailed record

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