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National Repository of Grey Literature 2 records found  Search took 0.00 seconds. 
Laboratory functional diagnostics of malabsorption syndromes with the focus on lactose intolerance
 Pluhařová, Apolena ; Kocna, Petr (advisor) ; Kohout, Pavel (referee)
This diploma thesis deals with laboratory functional diagnostics of malabsorption syndromes. Especially the functional diagnosis of lactose intolerance. The golden standard for the functional diagnosis of lactose intolerance is the breath test. The aim of the study was to determine the prevalence of lactose intolerance (LI) using a lactose breath test when consuming a dose of 20 g of lactose in patients with gastrointestinal symptoms and in volunteers who do not show gastrointestinal problems. Part of the research was also to examine the symptoms that led the individual to see a doctor and undergo a lactose breath test. The method consisted in the evaluation of the results of breath tests, which were performed on patients and volunteers in the gastroenterological laboratory of the 1st Medical Faculty of Charles University and the General Hospital. A questionnaire was given to everyone to evaluate the symptoms of LI and the phenomena leading to malabsorption. Lactose intolerance was confirmed in 92 % of patients and 79 % of volunteers. The most reported symptoms in the patient sample were typical gastrointestinal LI-related problems: gastric and intestinal problems after milk consumption (85 % of patients), gastric and intestinal problems after consumption of dairy products (85 % of patients),...
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Obesity and psychiatric diseases
 Pluhařová, Apolena ; Matoulek, Martin (advisor) ; Karbanová, Martina (referee)
Introduction: Obesity is closely related to psychiatric disorders. I examined a sample of obese patients who were on VLCD / LCD during hospitalization. The aim was to determine the incidence of psychiatric disorders among obese patients and the development of their weight. Methods: Quantitative research was carried out at the D3 department at III. Department of Internal Medicine, 1st Faculty of Medicine, Charles University and General Faculty Hospital in Prague. The data for the research was obtained from medical reports of patients on VLCD / LCD during hospitalization in the period 2018-2019. The results were compared with the Czech population and professional literature. Results: Data analysis shows that 42.2 % of women and 26.2 % of men in the sample suffer from a psychiatric diagnosis. The most common psychiatric disorder was depression and anxiety. The result of a comparison of a sample of patients on VLCD with the Czech population indicate that there is a similar proportion of depressive disorder among women on VLCD and individuals with obesity in the rest of the Czech population. In men, there is less incidence of depression on VLCD patients than in the rest of the population. A lower incidence of depressive disorder in men may be because individuals with severe psychiatric conditions are...
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2 Pluhařová, Alena
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