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Sand fly-borne viruses
Nedvědová Cvanová, Lucie ; Volf, Petr (advisor) ; Votýpka, Jan (referee)
Sand flies (Diptera: Psychodidae) are important vectors of protozoan, bacterial and viral patogens causing diseases in humans and domestic animals. This thesis summarizes the current knowledge on sand fly-born viruses, their distribution in the World, infection symptoms and life cycle in the nature. These viruses are transmitted by sand flies of genera Phlebotomus, Lutzomyia and Sergentomyia and they can be found on every continent except for Antarctica. They belong into four families, Bunyaviriae, Rhabdoviridae, Reoviridae and Flaviviridae, the most known and widespread is genus Phlebovirus from the family Bunyaviridae. Some of these sand fly-born viruses cause febrile illness, sometimes accompanied by acute meningoencephalitis (e.g. Toscana virus), while the others have not been proven to cause any disease in vertebrates. Animal reservoir of most of these viruses has not been found yet.
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