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Protilátky v terapii klíšťové encefalitidy
NEDVĚDOVÁ, Lenka
Tick-borne encephalitis (TBE) is a serious live threatening disease caused by tick-borne encephalitis virus (TBEV). The therapy is based on administration of non-specific treatment with anti-inflammatory drugs or IVIg (including non-specific antibodies). Application of non-specific antibodies may present a certain level of risk - maily of developing antibody dependent enhancement. We have developed and characterized monoclonal antibodies targetting non-structural protein 1 (NS1) of TBEV in order to assess its potential in TBEtreatment and diagnostics.
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Social work with adolescent children during a diagnostic stay
NEDVĚDOVÁ, Lucie
The bachelor thesis deals with the role of a key worker in a facility for children requiring immediate help. The work introduces legislative anchoring of this facility, characteristics of adolescence, course of stay in the facility and the role of a key worker. The concluding chapter describes the work of a key worker in the Children's Centre of the South Bohemia, which also includes an institution for children requiring immediate help
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Sand fly-borne viruses
Nedvědová Cvanová, Lucie ; Volf, Petr (advisor) ; Votýpka, Jan (referee)
Sand flies (Diptera: Psychodidae) are important vectors of protozoan, bacterial and viral patogens causing diseases in humans and domestic animals. This thesis summarizes the current knowledge on sand fly-born viruses, their distribution in the World, infection symptoms and life cycle in the nature. These viruses are transmitted by sand flies of genera Phlebotomus, Lutzomyia and Sergentomyia and they can be found on every continent except for Antarctica. They belong into four families, Bunyaviriae, Rhabdoviridae, Reoviridae and Flaviviridae, the most known and widespread is genus Phlebovirus from the family Bunyaviridae. Some of these sand fly-born viruses cause febrile illness, sometimes accompanied by acute meningoencephalitis (e.g. Toscana virus), while the others have not been proven to cause any disease in vertebrates. Animal reservoir of most of these viruses has not been found yet.
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Testing for suspected ingestion of addictive substances among primary school pupils in Jindřichův Hradec
NEDVĚDOVÁ, Ludmila
"Testing for suspected ingestion of addictive substances among primary school pupils in Jindřichův Hradec" thesis deals with the issue of addictive substances consumption among primary school pupils and the possibility in resolving this problem by schools itself. Theoretical part provides information about addiction causes, risks, which endanger youth in case of drugs consumption. Thesis also provides literature references and opportunity to look for different types of addictive substances. Furthermore, it deals with different kinds of addictive substances tests, their usage and level of results. Statutory framework of this issue is also discussed. Finally the thesis introduces options, which elementary schools use in solving this issue.
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Hodnota strategické flexibility
Nedvědová, Lenka ; Scholleová, Hana (advisor) ; Odcházel, Jiří (referee)
Diplomová práce se zabývá vlivem zahrnutí flexibility rozhodování do hodnoty investičních projektů. Popisuje reálně opční metodu hodnocení investic. Práce nejprve shrnuje teoretické poznatky finančních a reálných opcí, poté se zaměřuje na způsoby implementace metody reálných opcí do firemního rozhodování. Aplikační část je zaměřena na vyčíslení hodnoty opce čekání na základě rozdílných hodnot NPV včetně postupu, kterým je mozné určit hodnotu flexibility již v předinvestiční fázi.
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