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Interrelationship of basic biochemical parameters in patients of type II diabetes mellitus
Mazurová, Monika ; Mladěnka, Přemysl (advisor) ; Boušová, Iva (referee)
Diabetes mellitus 2nd tipe is heavy and very frequent civilizing disease in our population. The disease is characterized by hyperglycemia and other metabolism abnormalities are prezent. Assesment of glycemia in plasma (serum) is used for a diagnostics of the disease. Indicator of long- term compensation of diabetes is glycosylated haemoglobin. There were monitored possible dependensies between biochemical indicators in this work that are assesmented to diabetic patiens commonly. The dates were analyse from 54 diabetic patiens between the ages of 40 to 82 who visit a diabetic clinic periodically. The samples were analyzed by Cobas Integra 800 analyzer by Roche (Germany). Glucose in serum and in urine was analyzed by enzymatic metod with hexocinase and glycosylated haemoglobin was analyzed by imunochemical metod based on thurbidimetric inhibition in haemolysed blood. Paerson's correlative coefficient was used for appreciation of dependencies between variables. The highest correlative coefficient was found between glucose measuring in morning urine and glucosic losses by urine for 24 hours. Statistically important correlation were also found between glucose in serum and in urine or glucosic losses by urine for 24 hours and between glucose in serum and glycosylated haemoglobin. Because of relatively...
Interrelationship of basic biochemical parameters in patients of type II diabetes mellitus
Mazurová, Monika ; Boušová, Iva (referee) ; Mladěnka, Přemysl (advisor)
Diabetes mellitus 2nd tipe is heavy and very frequent civilizing disease in our population. The disease is characterized by hyperglycemia and other metabolism abnormalities are prezent. Assesment of glycemia in plasma (serum) is used for a diagnostics of the disease. Indicator of long- term compensation of diabetes is glycosylated haemoglobin. There were monitored possible dependensies between biochemical indicators in this work that are assesmented to diabetic patiens commonly. The dates were analyse from 54 diabetic patiens between the ages of 40 to 82 who visit a diabetic clinic periodically. The samples were analyzed by Cobas Integra 800 analyzer by Roche (Germany). Glucose in serum and in urine was analyzed by enzymatic metod with hexocinase and glycosylated haemoglobin was analyzed by imunochemical metod based on thurbidimetric inhibition in haemolysed blood. Paerson's correlative coefficient was used for appreciation of dependencies between variables. The highest correlative coefficient was found between glucose measuring in morning urine and glucosic losses by urine for 24 hours. Statistically important correlation were also found between glucose in serum and in urine or glucosic losses by urine for 24 hours and between glucose in serum and glycosylated haemoglobin. Because of relatively...

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1 MAZUROVÁ, Markéta
5 Mazurová, Martina
4 Mazurová, Michaela
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