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Analysis of the ELMART s.r.o. by the Selective Methods and Suggestions for Improving the Found Situation
Lhotská, Lenka ; Ing.Ludvík Rybář (referee) ; Hanušová, Helena (advisor)
This thesis is aimed at analysis of a selected company – ELMART s.r.o. The goal of the thesis is to formulate recommendations based on results of performed analyses and to suggest measures for improvement of the current state. Among the chosen methods of analysis are: PESTLE analysis, fundamental analysis, Kralick Quicktest, ratio analysis and SWOT analysis. The thesis is divided into a theoretical part, in which the characteristics of the chosen analysis methods are explained, and a practical part which deals with their processing. The conclusion of the thesis suggests recommendations based on results of performed analyses and aimed at improving the current state.
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Automatic Analysis of Heart Rate Variability Signals
Kubičková, Alena ; Halámek, Josef (referee) ; Lhotská, Lenka (referee) ; Kozumplík, Jiří (advisor)
This dissertation thesis is dedicated to the heart rate variability and methods of its evaluation. It mainly focuses on nonlinear methods and especially on the Poincaré plot. First it deals with the principle and nature of the heart rate variability, then the ways of its representation, linear and also nonlinear methods of its analysis and physiological and pathophysiological influence on heart rate variability changes. In particular, there is emphasis on the metabolic syndrome. In the next section of the thesis there are compared and evaluated different ways of representation of the heart rate variability and further are tested selected methods of heart rate variability analysis on unique data from patients with the metabolic syndrome and healthy subjects provided by the Institute of Scientific Instruments, Academy of Sciences of Czech Republic. In particular, they are used the Poincaré plot and its parameters SD1 and SD2, commonly used time domain and frequency domain parameters, parameters evaluating signal entropy and the Lyapunov exponent. SD1 and SD2 combining the advantages of time and frequency domain methods of heart rate variability analysis distinguish successfully between patients with the metabolic syndrome and healthy subjects.
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Possibility to simplify diagnostics and therapy of rare diseases in dentistry with the help of a database-based expert system in 2D and 3D images
Kratochvílová, Lenka ; Dostálová, Taťjana (advisor) ; Lhotská, Lenka (referee) ; Nováková, Květoslava (referee)
The possibility of simplifying the diagnostics and therapy of rare diseases in dentistry with the help of a database-based expert system in 2D and 3D imaging Abstract The present dissertation describes the methodology of creating a database of patients with rare diseases in the orofacial area. Clear and structured data are the basis for working with knowledge-based systems also in clinical practice. The use of database data is described for two specific diseases, namely Ectodermal Dysplasia and Zimmermann-Laband Syndrome. The methodology for working with the database consists of the steps of identifying a patient, adding a new card to the database, adding patient records and creating layouts. In the case of ectodermal dysplasia, a set of 13 Czech paediatric patients with ectodermal dysplasia presenting in the oral cavity was processed. The patients underwent genetic testing of candidate genes EDA, EDAR, EDARADD, TP63 and WNT10A. Three-dimensional facial scan images were taken of the patients and compared with facial scans of a healthy control group. The dental treatment of the patients was described using three of these patients as examples. Two patients with suspected Zimmermann-Laband syndrome were examined in both the genetic and dental departments despite not very pronounced manifestations of the...
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Relationship between metabolism, autonomic neuropathy and vascular disease in patients with type 1 and 2 diabetes mellitus
Malá, Šárka ; Keil, Radan (advisor) ; Lhotská, Lenka (referee) ; Krčma, Michal (referee)
The study aims to evaluate the relationship between cardiac autonomic neuropathy (CAN) and intima-media thickness (IMT) of carotid arteries in patients with diabetes mellitus. Individuals with type 1 and type 2 diabetes mellitus were included, with non-diabetic controls. Medical history, anthropometric and biochemical data, IMT measurements and heart-rate- variability (HRV) analysis in all probands were evaluated. A model of semiparametric logistic regression from the class of generalized additive models was used for statistical analysis. CAN demonstrated significant increasing effects on IMT values in type 1 diabetes patients. The model showed greater IMT values in type 2 diabetes mellitus patients suffering from CAN, but the effect of CAN was not significant. The interaction of CAN and diabetes mellitus effects on IMT values was proven. The interactions of CAN and age, CAN and BMI were also demonstrated. In CAN positive groups, IMT values increased more quickly with greater age and BMI. The results suggest that CAN may play a role in the pathogenesis of atherosclerosis in patients with diabetes mellitus. The secondary objective was to evaluate the usage of the recurrence quantification analysis of HRV in CAN diagnostics. Between the group of healthy individuals and patients with vasovagal...
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Effect of exercise training and Omega-3 fatty acids on body composition of elderly women
Sontáková, Lenka ; Šteffl, Michal (advisor) ; Holmerová, Iva (referee) ; Lhotská, Lenka (referee)
Title: Effect of exercise training and Omega-3 fatty acids on body composition of elderly women Objectives: The aim of this work is to determine the effect of combined aerobic and dynamic strength activity and supplementation of omega-3 fatty acids on body composition in women of senior age over 65 years. Methods: The intervention study included 53 women aged 65-80 years. The intervention lasted 4 months and before and after its onset, women underwent clinical examinations, anthropometry, bioimpedation examinations, AT biopsies, blood samples, DEXA and fitness testing. The intensity of physical activity was 1 hour 3 times a week. Of this, 1 hour was devoted to aerobic activity - Nordic walking and the remaining 2 hours to strength training. The group was also randomly divided into an omega-3 fatty acid moiety and a placebo moiety. Results: The average input and output values and changes in selected body composition indicators measured by INBODY show that exercise had a statistically significant positive effect on total weight, visceral fat and BMI in both groups. In contrast to the Calanus group, there was a statistically significant improvement in the control group also for proteins and total muscle mass. The additive positive effect of Calanem supplementation was not demonstrated for any...
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Medical devices certification
Množil, Lukáš ; Špunda, Miloslav (advisor) ; Lhotská, Lenka (referee)
This thesis is focused on verifying of safety of medical devices. In theoretical part there are analyzed general certification principles both European and International. There is also described the task of institutions involved in process, methods and general terms used by medical device certification. In the end ot this part, there is elaborated the general scheme describing and leading to successfull CE certification. In practical part there are described and elaborated basic stones of ECG Holter system documentation. There is accomplished analysis of requirements according to present standards and regulations. Safety attestation is verified through classification, validation and risk analysis. Output of the practical part is successfull ECG certification.
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Automatic Analysis of Heart Rate Variability Signals
Kubičková, Alena ; Halámek, Josef (referee) ; Lhotská, Lenka (referee) ; Kozumplík, Jiří (advisor)
This dissertation thesis is dedicated to the heart rate variability and methods of its evaluation. It mainly focuses on nonlinear methods and especially on the Poincaré plot. First it deals with the principle and nature of the heart rate variability, then the ways of its representation, linear and also nonlinear methods of its analysis and physiological and pathophysiological influence on heart rate variability changes. In particular, there is emphasis on the metabolic syndrome. In the next section of the thesis there are compared and evaluated different ways of representation of the heart rate variability and further are tested selected methods of heart rate variability analysis on unique data from patients with the metabolic syndrome and healthy subjects provided by the Institute of Scientific Instruments, Academy of Sciences of Czech Republic. In particular, they are used the Poincaré plot and its parameters SD1 and SD2, commonly used time domain and frequency domain parameters, parameters evaluating signal entropy and the Lyapunov exponent. SD1 and SD2 combining the advantages of time and frequency domain methods of heart rate variability analysis distinguish successfully between patients with the metabolic syndrome and healthy subjects.
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Analysis of the ELMART s.r.o. by the Selective Methods and Suggestions for Improving the Found Situation
Lhotská, Lenka ; Ing.Ludvík Rybář (referee) ; Hanušová, Helena (advisor)
This thesis is aimed at analysis of a selected company – ELMART s.r.o. The goal of the thesis is to formulate recommendations based on results of performed analyses and to suggest measures for improvement of the current state. Among the chosen methods of analysis are: PESTLE analysis, fundamental analysis, Kralick Quicktest, ratio analysis and SWOT analysis. The thesis is divided into a theoretical part, in which the characteristics of the chosen analysis methods are explained, and a practical part which deals with their processing. The conclusion of the thesis suggests recommendations based on results of performed analyses and aimed at improving the current state.
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Zhodnocení výrobní kapacity společnosti Barvy a laky Teluria s.r.o.
Lhotská, Lenka
Lhotská,L. Evaluation of the productive capacity of Barvy a laky Teluria, s.r.o. Bachelor thesis. Brno: Mendel University in Brno, 2014. The goal of this bachelor's thesis is to evaluate the productive capacity of Barvy a laky Teluria, s.r.o. in 2010-2013 and subsequent processing of suitable suggestions and recommendations for improvement. The first part is devoted to an explanation of theoretical concepts related to production activities of the enterprise, production capacity and capabilities of its calculation. The theoretical introduction is followed by a practical part, which contains characteristic of particular company and its production department. Then, capacity of production is calculated using the formulas. The total utilization of production possibilities is expressed by comparison of the resulting values with the values actually achieved, in the respective years. After comparison of the productive potential, suggestions and recommendations to improve the production capacity are mentioned. In the end of the thesis their consequences and implications for selected company are evaluated.
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