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Determination of pharmaceuticals in drinking waters using HPLC
Králová, Radka ; Čáslavský, Josef (referee) ; Vávrová, Milada (advisor)
The aim of the diploma thesis is the determination of macrolide antibiotics in drinking water by using of high performance liquid chromatography. Erythromycin and clarithromycin were selected such as representative macrolides due to frequently prescribed pharmaceuticals in this time. Solid phase extraction (SPE) by using of Oasis HLB cartridges was applied for pre concentration and purification of chosen analytes in real samples of drinking water. Optimalization of method and analysis were performed by using of high performance liquid chromatography with mass spectrometry detection (HPLC-MS). The suitable method was selected for determination of macrolides in real samples taken from two sources of drinking water, the interception of water in Litovel and Černovír Olomouc.
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Strakonice Castle and Commandery
Králová, Radka ; Záruba, František (advisor) ; Šmied, Miroslav (referee)
Theme of my thesis is Strakonice Castle and Commandry, where the House of Bavor and the Knights of Malta lived abreast for almost two centuries. Initially, my thesis will follow up the development of settlement of Prácheň region, especially of the Strakonice region, from the earliest times to 13th century. Next part of the thesis will introduce the House of Bavor and the Knights of Malta and their activities at the Strakonice castle. In conclusion, the thesis will deal with the foundation of Commandry and the castle, their subsequent architectural development and architectural analysis.
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Strakonice Castle and Commandery
Králová, Radka ; Záruba, František (advisor) ; Šmied, Miroslav (referee)
Theme of my thesis is Strakonice Castle and Commandry, where the House of Bavor and the Knights of Malta lived abreast for almost two centuries. Initially, my thesis will follow up the development of settlement of Prácheň region, especially of the Strakonice region, from the earliest times to 13th century. Next part of the thesis will introduce the House of Bavor and the Knights of Malta and their activities at the Strakonice castle. In conclusion, the thesis will deal with the foundation of Commandry and the castle, their subsequent architectural development and architectural analysis.
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The staff evaluation in Oblastní nemocnice Jičín a.s.
Králová, Radka ; Vaculíková, Barbora (advisor) ; Slanina, Petr (referee)
Diploma thesis deals with the assessment of performance appraisal of non-medical healthcare employees in Oblastní nemocnice Jičín a.s. . The thesis contents theoretical and practical part. The theoretical part anchors the performance appraisal system into the human resource management, with focus on the role of line managers. It also deals with the definition of job performance, circumstances that influence, and capabilities of its monitoring. Another part of the thesis emphasizes on the implementation of employee appraisal into practice, in which top management of the organization plays an important role. At the end of the theoretical part, I try to highlight the importance of linking of employee assessment with the vision, goals and values of the organization. The theoretical part offers the solution of the imperfections identified in the applied research. The practical part brings point of view on the reasons and way of implementation of employee appraisal in the organization, its adaptation by the employees and effectiveness of its use by the line managers. In this part I acquire pieces of knowledge through combination of qualitative and quantitative research. The research reveals the actual functioning of the system, imperfections in its implementation as well as line manager's suggestions for...
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Determination of pharmaceuticals in drinking waters using HPLC
Králová, Radka ; Čáslavský, Josef (referee) ; Vávrová, Milada (advisor)
The aim of the diploma thesis is the determination of macrolide antibiotics in drinking water by using of high performance liquid chromatography. Erythromycin and clarithromycin were selected such as representative macrolides due to frequently prescribed pharmaceuticals in this time. Solid phase extraction (SPE) by using of Oasis HLB cartridges was applied for pre concentration and purification of chosen analytes in real samples of drinking water. Optimalization of method and analysis were performed by using of high performance liquid chromatography with mass spectrometry detection (HPLC-MS). The suitable method was selected for determination of macrolides in real samples taken from two sources of drinking water, the interception of water in Litovel and Černovír Olomouc.
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