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Toxicity of selected nitramines
Papírek, Jan ; Fojt, Pavel (referee) ; Bednařík, Karel (advisor)
This Bachelor Thesis is focused on determination of toxicity of selected nitramines and nitrosoamines, which had to be synthesized soon. Out of total 10 prepared N-nitro and N- nitrosocompounds 4 were selected for testing their toxicity in test using Duckweed (Lemna Minor). Factor IC50 was determined for two compounds 3,7-dinitro-1,3,5,7-tetraazabicyclo [3.3.1]- nonane (DPT) and 3,7-dinitroso-1,3,5,7-tetraazabyciclo [3.3.1] nonane (DNPT), unfortunately factor for other compounds failed to determine, because conditions of test validity hadn’t been kept. In the end of the thesis is compared toxicity of N-nitro and N-nitrosocompounds based on results and observations.
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Use of terrestrial gastropods in ecotoxicity tests
Fojt, Pavel ; Komendová, Renata (referee) ; Kráčmar, Stanislav (referee) ; Zlámalová Gargošová, Helena (advisor)
The subject of this disertation is the use of terrestrial gastropods in ecotoxicity tests. Specifically, the use of a cosmopolitan terrestric gastropod Helix aspersa aspersa (syn. Cantareus aspersus or Cornu aspersum). The whole life cycle of this snail is very closely related the soil ekosystem. Here, the snails participates in some of the very important processes like the decomposition of the dead organic matter. This work is focused on the use of these snails to evaluate potential negative effect of some selected elements, which could, in different volumes, enter the soil ecosystem. The next task is to divide the ecotoxicity tests to different categories, depending on the life stage of this organism and then to compare the sensitivity of those life stages to different levels of contamination by certain pollutants.
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Toxicity of selected nitramines
Papírek, Jan ; Fojt, Pavel (referee) ; Bednařík, Karel (advisor)
This Bachelor Thesis is focused on determination of toxicity of selected nitramines and nitrosoamines, which had to be synthesized soon. Out of total 10 prepared N-nitro and N- nitrosocompounds 4 were selected for testing their toxicity in test using Duckweed (Lemna Minor). Factor IC50 was determined for two compounds 3,7-dinitro-1,3,5,7-tetraazabicyclo [3.3.1]- nonane (DPT) and 3,7-dinitroso-1,3,5,7-tetraazabyciclo [3.3.1] nonane (DNPT), unfortunately factor for other compounds failed to determine, because conditions of test validity hadn’t been kept. In the end of the thesis is compared toxicity of N-nitro and N-nitrosocompounds based on results and observations.
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