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Development of Human Resources Management
Lohniská, Aneta ; Floriánová, Monika (referee) ; Koleňák, Jiří (advisor)
The master´s thesis focuses on the theoretical field of human resources management, description of particular tools and their practical application in a particular company. The thesis describes the functioning of concrete personnel activities in the particular company and provides a proposal for increasing efficiency of personnel works.
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Molecular genetic analysis of the causes of selected hereditary forms of colorectal polyposis
Florianová, Martina ; Kohoutová, Milada (advisor) ; Křepelová, Anna (referee) ; Vodičková, Ludmila (referee)
Colorectal cancer (CRC) is one of the most common cancers worldwide. Hereditary colorectal adenomatous polyposis syndromes are a predisposition to colorectal carcinoma development. The most common analyzed syndromes are familial adenomatous polyposis (FAP) that results from germline mutations in the APC gene and MUTYH - associated polyposis (MAP) caused by germline mutations in the MUTYH gene. The aim of this study was to clarify genetics causes of colorectal polyposis in a set of probands without the germline mutation in the APC gene. Within studyʼs scope the presence of large deletion in APC gene was tested, there was looked for germline mutations in MUTYH gene, alternatively germline mutations in MSH6 gene by probands with monoallelic MUTYH mutation, item there was tested an effect of detected APC variants on gene expression. Screening for large deletions was performed by multiplex ligation dependent probe amplification (MLPA). A set of 120 APC-negative probands was examined for the presence of germline MUTYH mutations by denaturing high performance liquid chromatography (dHPLC). Subsequently a set of 145 APC-negative probands was screened only for germline MUTYH mutation in exon 7 and 13 by high resolution melting (HRM) analysis. Analysis of the effect on expression was tested by ten APC...
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Partition Coefficients Octanol-water of Selected (–)-Menthol-Substituted Chiral Ionic Liquids.
Andresová, Adéla ; Feder-Kubis, J. ; Florianová, M. ; Basarabová, B. ; Čubová, K. ; Bendová, Magdalena
Octanol-water partition coefficients, log P, may be considered as one of the indicators for the tendency to bioaccumulation. For this reason, log P was measured as a function of the alkyl chain length on the cation for selected species of the 1–[(1R, 2S, 5R)-(–)-menthoxymethyl]-3-alkylimidazolium chloride ionic liquid series. The data were processed by means of mathematical gnostics to evaluate the relationship between the structure of the studied ionic liquids and log P.
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The development of tourism in Třešť on the basis horseback riding
Florianová, Marie ; Syrovátka, Oldřich (advisor) ; Oberhel, Martin (referee)
This bachelor project is divided into theoretical and practical part. Theoretical part solves basic definition of tourism, assumptions, potential and process of creation of tourist product. Practical part analyzes actual situation of tourism in Třešť. The aim of the project is a proposal of a new tourist product, which is based on the analysis and on surveys. The main intention of the bachelor project is extension of the time spent by tourists in this location. It uses a natural potential, which the city has, while emphasizes a sustainable development. The product stands on analysis of assumptions, mutual cooperation and takes into account present segments of the guests (young couple and families with children) and actual preferences.
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Molecular genetic analysis of the causes of selected hereditary forms of colorectal polyposis
Florianová, Martina ; Kohoutová, Milada (advisor) ; Křepelová, Anna (referee) ; Vodičková, Ludmila (referee)
Colorectal cancer (CRC) is one of the most common cancers worldwide. Hereditary colorectal adenomatous polyposis syndromes are a predisposition to colorectal carcinoma development. The most common analyzed syndromes are familial adenomatous polyposis (FAP) that results from germline mutations in the APC gene and MUTYH - associated polyposis (MAP) caused by germline mutations in the MUTYH gene. The aim of this study was to clarify genetics causes of colorectal polyposis in a set of probands without the germline mutation in the APC gene. Within studyʼs scope the presence of large deletion in APC gene was tested, there was looked for germline mutations in MUTYH gene, alternatively germline mutations in MSH6 gene by probands with monoallelic MUTYH mutation, item there was tested an effect of detected APC variants on gene expression. Screening for large deletions was performed by multiplex ligation dependent probe amplification (MLPA). A set of 120 APC-negative probands was examined for the presence of germline MUTYH mutations by denaturing high performance liquid chromatography (dHPLC). Subsequently a set of 145 APC-negative probands was screened only for germline MUTYH mutation in exon 7 and 13 by high resolution melting (HRM) analysis. Analysis of the effect on expression was tested by ten APC...
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Development of Human Resources Management
Lohniská, Aneta ; Floriánová, Monika (referee) ; Koleňák, Jiří (advisor)
The master´s thesis focuses on the theoretical field of human resources management, description of particular tools and their practical application in a particular company. The thesis describes the functioning of concrete personnel activities in the particular company and provides a proposal for increasing efficiency of personnel works.
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Working Motivation of Nurses
FLORIÁNOVÁ, Michaela
Current status: The word motivation means to move. A motive is a factor that forces us to move ahead and meet our goals. The American Professor Frederick Herzberg dealt with motivation and compiled the motivation-hygiene theory of motivation. In this theory he focused on the satisfaction and dissatisfaction of respondents with work and the circumstances that led to those feelings. (2, 3). Subject: The aim of the research was to explore the extent to which hygiene (maintenance, external) and motivation (internal) factors affect job satisfaction of nurses. Methods: To obtain the necessary data for processing the thesis, quantitative research was used and it was conducted using a non-standardized questionnaire. Nurses and ward nurses in hospital wards in České Budějovice were involved. The theme of the questionnaire concerned the motivation and external factors according to Herzberg. The questionnaires were processed by SPSS, a non-parametric correlation test, and for evaluating the response rate a descriptive statistical function was applied. For statistical confirmation of the hypotheses was chosen 5% level of significance. Participants: In the study were included shift nurses and ward nurses in hospital wards in České Budějovice. A total of 250 questionnaires (100%) were distributed and 143 questionnaires were returned (57.2%). Nurses were contacted at the Department of Dermatology, ENT, ophthalmology, internal, surgical, rehabilitation, aftercare, ARO, children and urology wards. Results: The evaluation of the external factors of work motivation were observed in the following areas: policy and administration, relations with superiors, relationships with workers of the same level, salary, job security, personal life, working conditions and status. The results show that nurses are not satisfied with the wages (74.2%) and in their opinion, wages do not correspond with the work done (78.4%). Respondents pointed out that there are frequent conflicts within the team (52.5%) and lack of involvement in decision-making (57.4%). On the contrary, most nurses (92.3%) feel good among colleagues and say there is also a good atmosphere in the workplace (89.5%). Interpersonal relationships at work are also evaluated positively (88.8%) and the majority of nurses (93%) get along well with colleagues. The following areas were monitored within the evaluation of the motivational factors: recognition, promotion, work itself, the opportunity for personal growth and responsibility. Evaluation of the motivating factors revealed five negative areas. One of them is the stipulation of benefits given by the employer for work done above the norm; nurses responded that they do not receive these advantages (83.9%). According to the respondents, nurses do not have the opportunity for professional growth (51.1%) and promotion (74.2%). At the same time, in their opinion the occupation of a nurse is not considered prestigious (76.3%).They do not get recognition from superiors for successful or quality work (56.7%). On the contrary, a positive finding is that nurses have the option of continuing education (88.1%) and find self-fulfilment in their work (76.9%). Nurses get recognition from patients (62.2%). Conclusions and recommendations for practice: The results of the survey show that most nurses surprisingly answered both the motivation and external factors positively. The greater presence of external and motivation factors increased job satisfaction of the nurses. Their biggest problem was considered wages, which in the opinion of nurses does not correspond to the workload. The motivating factors fared best were training opportunities, good acceptation to the team and that the nurses enjoy the performed work and it suits them.
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Controlling as a method of control of an organization
FLORIÁNOVÁ, Milena
The diploma thesis under the title "Controlling as a method of control of an organization" is concentrated on controlling in a particular organization. The objective of this thesis is presentment of controlling as a method of control of an organization, whom an objective is reach of an planned society`s values. The theoretical part of the thesis presents the sence and tasks of controlling. The author presents calculations, planning, budgetes, business controlles because controlling is based on these systems. The practical part brings an analyse of controlling in a particular organization. In the conclusion, the particular organization controlling arrangement is assessed, and appropriate changes for the organization are suggested.
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The Methodology and Objectives of Internal Accounting in Particular Organization
FLORIÁNOVÁ, Milena
The bachelor thesis under the title ``Methodology and Objectives of Internal Accounting{\crqq} is concentrated on internal accounting analysis in a particular organization. The objective of this thesis is to compare the reality with general terms of internal accounting, determinate differences between them and, consequently, to suggest appropriate changes for the organization. The theoretical part of the thesis presents the general description of internal accounting arrangement, i.e. its concentration, tasks, objectives, forms and functions. The practical part brings into focus a particular organization. An analysis of internal accounting arrangement of that organization is given there. It deals with cost and profit centres accounting, internal orders, output analysis, and internal assessment, calculations, planning and statement evidence. In the conclusion, the particular organization internal accounting arrangement is assessed, and appropriate changes for the organization are suggested.
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