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Biological Activities and Chemical Content of Glycyrrhiza Species
Cheel Horna, Jose Carlos ; Tůmová, Lenka (advisor) ; Sikyta, Bohumil (referee) ; Mučaji, Pavel (referee)
7. ABSTRACT 7.1. Phenolic content profiles and free radical-scavenging activity of roots of Glycyrrhiza species In this study, the free radical-scavenging activity of 80% methanolic extracts from G. glabra, G. uralensis, G. echinata, and G. pallidiflora roots was assessed using DPPH free radical and superoxide anion radical scavenging assays. The total contents of phenolics (TP), flavonoids (TF), and tannins (TT) were also measured. From the results, G. glabra showed the highest DPPH radical scavenging activity (DRSA), whereas G. echinata exhibited the lowest values of DRSA. Extracts from G. uralensis, G. echinata, and G. pallidiflora showed the highest superoxide radical scavenging activity (SRSA). The highest TP content was found out in G. uralensis and G. echinata (4.71 and 4.70 mg gallic acid equivalents/100 mg of extract, respectively). The highest TF content (1.84 mg quercetin equivalents (QE)/100 mg of extract) was observed in G. glabra, whereas the lowest value (0.53 mg QE/100 mg of extract) was measured in G. pallidiflora. Extracts from G. uralensis and G. pallidiflora showed the highest TT content. There were positive and significant correlations between TP and SRSA (r = 0.6881, p < 0.05) and between TT and SRSA (r = 0.7754, p < 0.05). The TF content was significantly correlated only with DRSA (r...
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Biological Activities and Chemical Content of Glycyrrhiza Species
Cheel Horna, Jose Carlos ; Tůmová, Lenka (advisor) ; Sikyta, Bohumil (referee) ; Mučaji, Pavel (referee)
7. ABSTRACT 7.1. Phenolic content profiles and free radical-scavenging activity of roots of Glycyrrhiza species In this study, the free radical-scavenging activity of 80% methanolic extracts from G. glabra, G. uralensis, G. echinata, and G. pallidiflora roots was assessed using DPPH free radical and superoxide anion radical scavenging assays. The total contents of phenolics (TP), flavonoids (TF), and tannins (TT) were also measured. From the results, G. glabra showed the highest DPPH radical scavenging activity (DRSA), whereas G. echinata exhibited the lowest values of DRSA. Extracts from G. uralensis, G. echinata, and G. pallidiflora showed the highest superoxide radical scavenging activity (SRSA). The highest TP content was found out in G. uralensis and G. echinata (4.71 and 4.70 mg gallic acid equivalents/100 mg of extract, respectively). The highest TF content (1.84 mg quercetin equivalents (QE)/100 mg of extract) was observed in G. glabra, whereas the lowest value (0.53 mg QE/100 mg of extract) was measured in G. pallidiflora. Extracts from G. uralensis and G. pallidiflora showed the highest TT content. There were positive and significant correlations between TP and SRSA (r = 0.6881, p < 0.05) and between TT and SRSA (r = 0.7754, p < 0.05). The TF content was significantly correlated only with DRSA (r...
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