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National Repository of Grey Literature 2 records found  Search took 0.01 seconds. 
Pharmacological approach to the results of the estrogen and progesterone receptors in the breast tumours.
 Bařinková, Vlasta ; Hochmann, Jiří (advisor) ; Bunček, Martin (referee)
In the part devoted to discussion of different authors about the importance of the progesterone receptor (PR) value we concentrated primarily to the works of foreign authors published in professional journals. We divided the opinions of this experts to such, which show that PR testing is needless and to the part about profitability of this testing. In the chapter about importance PR testing some authors critize, that some patients - negative in estrogen receptors (ER) (such of them that are simultaneously PRpositive) could be deprived in the possibility of hormonal therapy, because PR testing wouldn't be made. And in the addition, the other - (in this case) the less effective treatment would be given them preferentially. PR testing is important also for detection of the group of ER-positive tumors with PR negativity. At this group is the smaller possibility that the tumors would respond to the hormonal treatment (in contrast to ER+/PR+). In the part devoted to gene therapy we described first the information about learning from the textbooks. Futher we describe different modes of classification of the gene therapy of the breast cancer in the foreign literature. We modified their classification further according to our necessity to these subheads: (1) mutation compensation of differentiation genes,...
Detailed record
Pharmacological approach to the results of the estrogen and progesterone receptors in the breast tumours.
 Bařinková, Vlasta ; Hochmann, Jiří (advisor) ; Bunček, Martin (referee)
In the part devoted to discussion of different authors about the importance of the progesterone receptor (PR) value we concentrated primarily to the works of foreign authors published in professional journals. We divided the opinions of this experts to such, which show that PR testing is needless and to the part about profitability of this testing. In the chapter about importance PR testing some authors critize, that some patients - negative in estrogen receptors (ER) (such of them that are simultaneously PRpositive) could be deprived in the possibility of hormonal therapy, because PR testing wouldn't be made. And in the addition, the other - (in this case) the less effective treatment would be given them preferentially. PR testing is important also for detection of the group of ER-positive tumors with PR negativity. At this group is the smaller possibility that the tumors would respond to the hormonal treatment (in contrast to ER+/PR+). In the part devoted to gene therapy we described first the information about learning from the textbooks. Futher we describe different modes of classification of the gene therapy of the breast cancer in the foreign literature. We modified their classification further according to our necessity to these subheads: (1) mutation compensation of differentiation genes,...
Detailed record

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