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Oximes as Drugs
Švehlová, Jana ; Opletalová, Veronika (advisor) ; Miletín, Miroslav (referee)
Name: Jana Švehlová Title: Oximes as Drugs Thesis Charles University in Prague, Faculty of Pharmacy in Hradec Králové Programme: Pharmacy This thesis aims at the processing data about existing and potential drugs of the oximes and amidoximes groups. First section contains information on existing drugs; second section focuses on the potential chemicals from the groups of oximes and amidoximes For the most part, oximes have been used as acetylcholinesterase-reactivating agents. The oxime group is contained in the structure of the macrolide antibiotic roxithromycin (RX) and also in the structure of some cephalosporin antibiotics of the second, third and fourth generation. Another representative of oximes used in pharmacotherapy is the antidepressant fluvoxamine, a selective serotonin reuptake inhibitor (SSRI). Potential pharmaceuticals influencing the cardiovascular system include istaroxime and its analogues which are positively inotropic. Formamidoxime, acetohydroxamic acid and formamidoxime function as nitric oxide donors and certain oximes may reduce cholesterol levels in blood. Oximes, whose molecules contain 5-benzyl-2,4-thiazolidinedione, and newer oximes in which the thiazolidinedione has been substituted with α-substituted β-phenylpropionic moiety may be used for treating diabetes. Oximes...
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The hazards of soil pollutants and their effects on the human health
ŠVEHLOVÁ, Jana
Good soil condition belongs to the basic requirements of well-ballanced environment. That is why the soil has to correspond to hygienic requirements and be protected against substances harmful to human health, e.g. toxic materials, germs of transmissible illnesses and parasites. The most common cause of soil contamination is anthropogenic incidence. Contaminated soil belongs to waste and has to be removed in a proper way. is A special way of waste removal is soil decontamination. Its goal is to remove harmful substances and regain the original use of the soil.
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SENIOR´S NOURISHMENT IN THE RETIREMENT HOUSES IN THE REGION OF SOUTH BOHEMIA
ŠVEHLOVÁ, Jana
This Bachelorś these should have shown the situation of senior´s nourishment in the retirement houses in the region of South Bohemia. I have made quantitive research in the form of questionare and used it as a basis for this work. From the result of this research has been found the conclusion, tkat the nourishment in the retirement houses is satisfied. Even so I would recommend to the leadership of retirement houses to join the Project called Standardization of Nutritional Care in Old People´s Homes.
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