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Mixture toxicity of estrogenic endocrine disruptors in samples from the Czech Republic
Černá, Tereza ; Cajthaml, Tomáš (advisor) ; Klusoň, Petr (referee) ; Šváb, Marek (referee)
The environment is contaminated by countless toxic chemicals of mainly anthropogenic origin; therefore, elucidating the impact of chemical mixtures is one of the biggest challenges of current research. Endocrine disruptors (EDs) acting through the oestrogenic nuclear receptor are typical representatives of the mixture toxicity concept of concentration addition, which can be accurately predicted using the latest mathematical models. Oestrogenic activity and oestrogenic EDs have been detected in many matrices across the globe in biologically relevant concentrations; therefore, they are considered a high risk. The presence of synthetic steroids in the aquatic environment in units of ng/l can disrupt the hormonal pathways of individuals and subsequently cause fatal changes in whole populations. However, if the exposure is terminated, the ecosystem will recover in a few years. Wastewater treatment plants (WWTPs) are able to remove a large number of chemicals, including synthetic and natural oestrogenically active compounds; nevertheless, their occurrence in WWTP effluents and in sewage sludges is frequent. Therefore, WWTPs are considered significant sources of agricultural and water ecosystem pollution. This dissertation thesis focuses on the mixture toxicity of oestrogenic EDs and their occurrence in...
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Advanced remediation technologies for recalcitrant pollutants
Lhotský, Ondřej ; Cajthaml, Tomáš (advisor) ; Šváb, Marek (referee) ; Chrastný, Vladislav (referee)
Advanced remediation technologies for recalcitrant pollutants Studium pokročilých sanačních technologií pro rekalcitrantní polutanty Dissertation thesis Ing. Ondřej Lhotský Abstract This study focuses primarily on the testing and optimization of methods based on modifications to, and the targeted enhancement of, natural microbial processes for the removal of recalcitrant pollutants. Pilot tests were conducted of these innovative methods at real contaminated sites and matrices, and their effectiveness was monitored in the relevant environments. The pilot tests generally confirmed the potential of the modifications and bioremediation technology combinations by revealing significant increases in the removal efficiency for a number of recalcitrant contaminants. The study provides a general summary of the issue of soil and rock environment contamination by recalcitrant contaminants and familiarizes the reader with bioremediation technologies and their optimization for the removal of recalcitrant contaminants. Subsequently, a theoretical introduction is provided of the methods applied in 4 pilot tests of optimized and combined remediation methods at real contaminated sites in the Czech Republic. The pilot tests are described in detail in publications 1, 2, 4 and 5. Publication 6 covers a pilot test conducted on...
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Production of an alternative fuel from digestate using bio-drying method
Rákosník, Vítězslav ; Innemanová, Petra (advisor) ; Šváb, Marek (referee)
Biogas represents one of the renewable sources of energy, which has been growing on use rapidly over the past decades. Biogas is produced during anaerobic digestion of organic material in biogas plants and it is most frequently used for heat and electricity production purposes. There are still plenty of unresolved questions as it is with the other renewable sources of energy. One of the most actual topics is the question of the subsequent usage of a digestate - side product of the biogas production process. Digestate is generally applied as an organic fertilizer for farmlands, but there are tendencies to use its solid phase for another energy producing processes or eventually as farm animal bedding, which is unfortunately connected with few problematic aspects such as transportation and storing of the biologically unstable material with high amount of water in it. Answer to those challenges could be provided by the bio-drying of the digestate's solid phaze - substrate is dried up by heat produced during the microbial decomposition of organic matter and artificial aeration. The main objective of the experimental part of this thesis was to comprehensively test the process of bio-drying of unmodified solid phase of digestate from different biogas plants with agricultural origin for the purpose of...
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Business plan
Vítová, Helena ; Krause, Josef (advisor) ; Šváb, Marek (referee)
The object of this thesis is to develop a feasible business plan establishing a children's patisserie named Drak situated in Trutnov. It describes requisites of property rights, ownership structure, SWOT analysis, marketing and financial plan. The thesis is divided into two parts, theoretical and practical. The theoretical part is responsible for defining the key concepts of business plan, its structure and further it describes the methodology that is used in the practical part. The practical part of this thesis contains a business plan itself, which implements the business plan of establishing a children's patisserie. In conclusion the business plan is evaluated and the possibility of putting it into practice is analyzed.
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