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Microwave transverter for 5 760 MHz to 146 MHz
Šustr, Jan ; Šnajdr, Václav (referee) ; Lukeš, Zbyněk (advisor)
This work deals with a design of the microwave transverter for 5 760 MHz to 146 MHz. It is divided to a few parts. The first one is focused to design of the local oscillator which generates the signal at frequency f = 116.9583MHz. The oscillator is designed like a crystal oscillator. Its output signal is multiplied and amplified in a second part. The next parts deal with design of the band pass filters. There I chose the design of the filters and did the measurements. The microwave receiver and transmitter circuits are designed with the modern monolithic circuits. The main job of this part is to design low noise amplifier and the power amplifier. At the end of this work I do the measurements and the comparison with the simulations.
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The Role of Genetic Mutations in Breast Cancer
Šustr, Jan ; Fínek, Jindřich (advisor) ; Petráková, Katarína (referee) ; Prausová, Jana (referee)
Introduction: About 5 - 10% of breast carcinomas are caused by genetic mutations. The most common genetic mutation that is involved in the development of this malignancy is a mutation in the tumor suppressor genes BRCA1/2 whose carriers have approximately a 70% lifetime risk of developing breast cancer. The prognosis of patients with BRCA1/2-asociated breast carcinoma, compared to patients with sporadic breast carcinoma is the subject of many studies with ambiguous results. Aim: The aim of the theoretical part of this work was to approach the issue of breast cancer and the most common genetic syndromes associated with it. In the practical part of this work a retrospective study was carried out in order to compare BRCA1/2 mutated breast cancer patients with non-mutated breast cancer patients in the tumor profile, methods of treatment and prognosis. Methods: We retrospectively analyzed the data of 134 patients who were tested for the presence of BRCA1/2 mutation at the Institute of Medical Genetics, University Hospital in Pilsen during the years 2013-2018 and at the same time were treated for early breast cancer at the University Hospital in Pilsen during the years 2000-2020. 32 patients were BRCA1 positive (24%), 10 BRCA2 positive (7%) and 92 without BRCA1/2 mutation (69%). The follow- up time was...
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Microwave transverter for 5 760 MHz to 146 MHz
Šustr, Jan ; Šnajdr, Václav (referee) ; Lukeš, Zbyněk (advisor)
This work deals with a design of the microwave transverter for 5 760 MHz to 146 MHz. It is divided to a few parts. The first one is focused to design of the local oscillator which generates the signal at frequency f = 116.9583MHz. The oscillator is designed like a crystal oscillator. Its output signal is multiplied and amplified in a second part. The next parts deal with design of the band pass filters. There I chose the design of the filters and did the measurements. The microwave receiver and transmitter circuits are designed with the modern monolithic circuits. The main job of this part is to design low noise amplifier and the power amplifier. At the end of this work I do the measurements and the comparison with the simulations.
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Bankruptcy prediction models
Šustr, Jan ; Synek, Miloslav (advisor) ; Špička, Jindřich (referee)
The aim of this thesis is to describe some of the well-known, as well as several less-known, prediction models, and to verify their ability of predicting bankruptcy in the conditions of the Czech Republic. The theoretical part of the thesis contains descriptions of these models, equations to calculate them and ways of results evaluation. Models by both Czech and foreign authors are presented. The practical part of the thesis verifies the ability of these models to predict bankruptcy on a sample of eight randomly selected companies which suffered serious financial problems. At the end of this thesis, the results from evaluating of these companies by prediction models are summarized.
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Elektronické mýtné v Londýně
Šustr, Jan ; Zelený, Lubomír (advisor) ; Gabrielová, Lenka (referee)
Práce analyzuje systém elektronického mýtného v Londýně, popisuje postup při zavádění systému, použité technologie, systém poplatků, především se však zaměřuje na zhodnocení dopadů zavedení tohoto systému na dopravu v Londýně, hodnotí i ekologické dopady a ekonomickou efektivnost systému.
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