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National Repository of Grey Literature 2 records found  Search took 0.00 seconds. 
Enantioselective synthesis of functionalized cyclopentanes
 Šotolová, Martina ; Veselý, Jan (advisor) ; Matoušová, Eliška (referee)
This diploma thesis deals with the synthesis of chiral five-membered carbacyclic molecules via iminium-enamine activation using chiral secondary amines. The first part of thi diploma thesis describes the synthesis of starting materials for domino Michael addition/α-alkylation reaction, i.e. the synthesis of α,β-unsaturated aldehydes and 1-bromo-3-nitropropane. The second part of this diploma thesis is focused on the optimization of reaction conditions and the application of the domino Michael addition/α-alkylation reaction, that leads to the formation of cyclopentancarbaldehydes with contiguous stereogenic centres. Key words Asymmetric synthesis, organocatalysis, domino reaction, Michael addition, cyclopentanes.
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Preparation of bifunctional thiourea organocatalysts containing saccharide unit
 Šotolová, Martina ; Veselý, Jan (advisor) ; Míšek, Jiří (referee)
This bachelor thesis deals with the synthesis of bifunctional thiourea-phosphine catalysts and corresponding building blocks derived from D-glucose and α-amino acid L-threonine. The first part of this thesis is focused on the preparation of glucopyranosylisothiocyanates and aminophosphines. The second part of the thesis deals with the preparation and the application of prepared bifunctional catalyst.
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See also: similar author names
1 ŠOTOLOVÁ, Mirka
3 Šotolová, Markéta
1 Šotolová, Michaela
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